After reading these articles:
I am inclined to think that obesity COULD BE caused by altered gut flora. By taking antibiotics, ingesting grains and sugar as well as other processed foods we are 1. reducing our beneficial bacteria 2. helping our pathogenic bacteria to multiply (and kill off our little friendly guys).
So, if this is the case, the solution must be to isolate the types of bacteria that help skinny people to stay skinny and figure out how to re-populate the gut flora of people who want to lose weight with it. It can be added to everything - burgers, sweet potato fries, ice-cream...
Can I have my Nobel prize now? :)
I actually saw a brand of ice-cream with probiotics - they sell it our local pharmacy. At $20 per a very small container people are not buying it.
No, really, how plausible is this GAOS (Gut and Obesity Syndrome) theory?
asked byVB (15515)
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on September 16, 2012
at 09:38 PM
At 450lbs, a blue-baby, who had Meningitis as an toddler and was consequently given antibiotics at dosages that look like a weekly dosage for an adult every hour via IV I'd say a correlation isn't impossible. I fit the pattern anyway.
I don't think it is as easy a probiotics, as far as I've seen no study to date shows that probiotics do much to change the established biome. I suspect a massive dose of of broad spectrum antibiotics combined with fasting and supplemental s. boulardi might combine to wipe out your guy flora completely enough so that immensely high pro-biotic replacement might work. Even fecal transplantation.
I won't be the first to try this however....
on September 17, 2012
at 12:13 AM
Bill said in his answer: "Every fat person got there the same exact way. Waaay too much sugar and fat combined. McDonalds, Big Gulps, Snickers Bars and Grease - together = 'Insidious Fat Gain"
Such a diet has made many quite rotund. Most wouldn't disagree on this. But what about the people who don't become obese on such a diet? I know many who haven't. With such a diet it's hard to eat only your basic calorie needs, but some people do. How? A hardy metabolic rate helps. I also suspect some people have quite the capacity for unconscious regulation of appetite. In the context of this question, perhaps a good micrbiome contributes to the production of short chain fats like buytric acid which may strongly modulate body weight:
Conversely, what about people with severe gut dysbiosis? Could increased intestinal permeability allow psychoactive substances to pass into our blood stream and disrupt satiety signals? I wouldn't be surprised. Could bacterial toxins contribute to liver damage, raising triglycerides, thereby increasing leptin resistance? It's speculative, but maybe.
I support calories in calories as the determining factor in weight gain/loss, but to say CICO is the whole story is like saying "It was the best of times it was the worst of times" is all there is to A Tale of Two Cities.
I think future research will continue to unravel the complexities of our microbiome and reveal to us how truly important our gut bacteria is in making us sick or healthy.
For anyone interested, Lucas Tafur writes a lot on this particular subject: http://www.lucastafur.com/2012/03/nutritional-immunotherapy-overview.html
on September 16, 2012
at 11:55 PM
HFCS, Big Gulps, Anything in cellophane, video games, Tv, Our mind-body dissociation, wheat, O6 seed oils, reduced dependence on movement, DRUGS, our current medical paradigm, pain, mental, physical, and emotional dysfunction.
on September 16, 2012
at 11:19 PM
Giving little Fat People even more food and HFCS is what is causing obesity, AND video games.
Every fat person got there the same exact way. Waaay too much sugar and fat combined. McDonalds, Big Gulps, Snickers Bars and Grease - together = 'Insidious Fat Gain'
Typical fat kid diet: Rice Krispies with whole milk, high fat sausuge, bagel, orange juice for breakfast. Pizza or some crappy noodle dish slathered with fat for lunch. Snack - HFCS, Doritos, and or fried chicken fingers with insulin blasting sauce of some kind. Dinner, whatever their fat parents are eating, but guaranteed, its fat+lots of carbs.
THAT is what is creating these humongous 200-300-400-500 lbers.
And "Finish your plate or sit there til its gone, there are starving children is Africa" - Parents who use guilt make me sick.