I experiment lately with intermittent fasting and I have the impression that when I eat my limited (1200 kcal) food in a 5 hour window I lose more weight than when I distribute it in the whole day. Does this possibly have a biochemical explanation involving insulin and other hormones or do I have to buy a new scale?
asked bygiacinto (571)
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on February 23, 2013
at 02:53 PM
Best explanation ever:
According to Maughan et al. (Maughan. 2010) the "early phase of fasting" comprises roughly 24h and is characterized by sufficient glycogen supply from the liver with the liver releasing about 4g of glucose per hour in the initial phase of fasting. In oder to spare the precious glycogen stores (Maughan estimates the average liver glycogen stores with only 44g/kg liver tissue, or about 60g for an average human liver) an upregulation in fatty acid oxidation takes place even in this early stages of fasting (Cahill. 1966). Consequently the concentration of circulating free fatty acids and glycerol (both released from white adipose tissue) in the blood increases and fatty acids and glycerol become available as a potential alternate fuel source for muscle and substrate for glyconeogenesis in the liver.
In other words, when you aren't eating, you're burning. The positive metabolism enhancing effects start at around 6 hours and continue to elevate for a period of DAYS (full fast).