2

votes

What are the news on Vitamin K1 and 2?

Answered on August 19, 2014
Created July 01, 2011 at 3:47 PM

Is there any new knowledge on vitamin K1 and K2 and derivates. MK7 MK8...

What are good source for Vitamin K? Organ meat, butter...

Is there source which are more uncomon. Maybe like insect bugs, fermented foods, exotic foods from remoted areas in the world, or wild edible herbs which are high in vitamin K.

Good known vegan source for Vitamin K2 is Natto, which are fermented soybeans. Do you know other plant sources of vitamin K2. Maybe exotic from other cultures?

4164a77c7ccf4839ec7f1e665d27cc6d

(1085)

on July 02, 2011
at 09:23 PM

so you're telling me you missed the casting call?

696079a860ef54810406ae25e4650863

(1623)

on July 02, 2011
at 09:04 PM

Yeah, I tend to be cautious as well. Even though I can at least see the argument that in extreme cases of deficiency ultra high 'Therapeutic' doses can be useful, it still makes me wonder if youre just not throwing something else out of whack. Lately I've been reducing the amounts of supplements I take and giving any ones that remain some real scrutiny.

77877f762c40637911396daa19b53094

(78467)

on July 02, 2011
at 05:59 PM

funny craig i often pass the institute here in heidelberg germany. its the DKFZ

E5c7f14800c5992831f5c70fa746dc5c

(12857)

on July 02, 2011
at 05:58 PM

http://www.google.com/products/catalog?hl=en&safe=off&q=menatetrenone&biw=1020&bih=638&um=1&ie=UTF-8&tbm=shop&cid=9142881426882008410&sa=X&ei=L1wPTrydIePiiALxn_Vg&ved=0CC0Q8wIwAQ

77877f762c40637911396daa19b53094

(78467)

on July 02, 2011
at 05:54 PM

Where do get MK4 from?

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 02, 2011
at 01:27 PM

I just use google scholar. In general, I'm very cautious about doses and forms of vitamins/minerals that are not obtainable in foods in similar amounts. People are arrogant and think they know much more than they do. So many examples over the years of supplements doing harm any time anyone takes a close look...

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 02, 2011
at 01:27 PM

I just use google scholar. In general, I'm very cautious about doses and forms of vitamins/minerals that are not obtainable in foods in similar amounts. People are arrogant and think they know much more than they do. So many examples over the years of supplements doing harm any time any takes a close look...

696079a860ef54810406ae25e4650863

(1623)

on July 02, 2011
at 06:35 AM

Yeah- I need to review them myself more thoroughly- the results seem so promising, but I wonder about the efficacy of lower doses... so many articles, so little time. At least google scholar makes it easier to sort through. Do you use any other resources to find pubmed articles? I'm always looking for access to good inormation... Thanks :)

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 02, 2011
at 01:45 AM

Think those are the ones with megadoses I mentioned.

696079a860ef54810406ae25e4650863

(1623)

on July 02, 2011
at 12:51 AM

Hey Jay- I remembered hearing about human trials with the MK4 form of K2 when doing some research for my mom's osteoporosis. Not sure if you'd seen these or not, but thought I'd post the link just in case others were interested. http://scholar.google.com/scholar?q=Menatetrenone&hl=en&btnG=Search&as_sdt=1%2C5&as_sdtp=on

0dbd7154d909b97fe774d1655754f195

(16131)

on July 02, 2011
at 12:09 AM

I realize I should have made this a comment rather than an answer.

77877f762c40637911396daa19b53094

(78467)

on July 01, 2011
at 07:52 PM

Sly Stallone, who would want to look like him when you could look like Chris Kresser? ;)

77877f762c40637911396daa19b53094

(78467)

on July 01, 2011
at 07:50 PM

Yes, meredith, I am very curious to hear about your results of the potato juice scramble. That is fascinating stuff.

0dbd7154d909b97fe774d1655754f195

(16131)

on July 01, 2011
at 07:45 PM

In potato juice scramble by any chance? I am going to try that. I'll let you know how it turns out.

A968087cc1dd66d480749c02e4619ef4

(20436)

on July 01, 2011
at 05:55 PM

Gonna look like Sly Stallone soon!

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5 Answers

2
E5c7f14800c5992831f5c70fa746dc5c

(12857)

on July 01, 2011
at 11:49 PM

Only MK-4 is implicated in bone health and it is the x-factor in spring butter.

Vitamin K1 is converted to MK-4 in the body. Pre-formed is probably more optimal but who knows. I take 5mg of MK-4 almost everyday, I want to make sure I load up for all those years I missed out.

77877f762c40637911396daa19b53094

(78467)

on July 02, 2011
at 05:54 PM

Where do get MK4 from?

E5c7f14800c5992831f5c70fa746dc5c

(12857)

on July 02, 2011
at 05:58 PM

http://www.google.com/products/catalog?hl=en&safe=off&q=menatetrenone&biw=1020&bih=638&um=1&ie=UTF-8&tbm=shop&cid=9142881426882008410&sa=X&ei=L1wPTrydIePiiALxn_Vg&ved=0CC0Q8wIwAQ

2
4164a77c7ccf4839ec7f1e665d27cc6d

(1085)

on July 01, 2011
at 07:13 PM

Although not directly answering your question, this may be of interest:

From Chris Kresser "A study recently published by the European Prospective Investigation into Cancer and Nutrition (EPIC) has revealed that increased intake of vitamin K2 may reduce the risk of prostate cancer by 35 percent. The authors point out that the benefits of K2 were most pronounced for advanced prostate cancer, and, importantly, that vitamin K1 did not offer any prostate benefits.

The findings were based on data from more than 11,000 men taking part in the EPIC Heidelberg cohort. It adds to a small but fast-growing body of science supporting the potential health benefits of vitamin K2 for bone, cardiovascular, skin, brain, and now prostate health."

Full article:Vitamin K2: The Missing Nutrient

4164a77c7ccf4839ec7f1e665d27cc6d

(1085)

on July 02, 2011
at 09:23 PM

so you're telling me you missed the casting call?

77877f762c40637911396daa19b53094

(78467)

on July 02, 2011
at 05:59 PM

funny craig i often pass the institute here in heidelberg germany. its the DKFZ

1
4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 01, 2011
at 06:19 PM

There's no clinical trial data on K2 in humans that I am aware of, except for trials using mega doses (orders of magnitude larger than what you could possibly obtain from food).

That said, there is decent epidemiological data for K2 (generally from mk-7) from the EPIC study suggesting some reduction in risk of cancer and heart disease; this generally reflects cheese consumption.

There is some clinical data on K1 in humans, suggesting it is safe in low doses and, in combination with vitamin D, may help reduce bone loss and maybe cancer (maybe by a lot).

At this point, I recommend a very low dose supplement that combines (or alternates) these 3 forms. Once per week (on different days) I take 45mcg of mk-7, 100 mcg of mk-4, and 100 mcg of k1.

696079a860ef54810406ae25e4650863

(1623)

on July 02, 2011
at 06:35 AM

Yeah- I need to review them myself more thoroughly- the results seem so promising, but I wonder about the efficacy of lower doses... so many articles, so little time. At least google scholar makes it easier to sort through. Do you use any other resources to find pubmed articles? I'm always looking for access to good inormation... Thanks :)

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 02, 2011
at 01:45 AM

Think those are the ones with megadoses I mentioned.

696079a860ef54810406ae25e4650863

(1623)

on July 02, 2011
at 12:51 AM

Hey Jay- I remembered hearing about human trials with the MK4 form of K2 when doing some research for my mom's osteoporosis. Not sure if you'd seen these or not, but thought I'd post the link just in case others were interested. http://scholar.google.com/scholar?q=Menatetrenone&hl=en&btnG=Search&as_sdt=1%2C5&as_sdtp=on

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 02, 2011
at 01:27 PM

I just use google scholar. In general, I'm very cautious about doses and forms of vitamins/minerals that are not obtainable in foods in similar amounts. People are arrogant and think they know much more than they do. So many examples over the years of supplements doing harm any time anyone takes a close look...

4781cf8ae1bfcb558dfb056af17bea94

(4359)

on July 02, 2011
at 01:27 PM

I just use google scholar. In general, I'm very cautious about doses and forms of vitamins/minerals that are not obtainable in foods in similar amounts. People are arrogant and think they know much more than they do. So many examples over the years of supplements doing harm any time any takes a close look...

696079a860ef54810406ae25e4650863

(1623)

on July 02, 2011
at 09:04 PM

Yeah, I tend to be cautious as well. Even though I can at least see the argument that in extreme cases of deficiency ultra high 'Therapeutic' doses can be useful, it still makes me wonder if youre just not throwing something else out of whack. Lately I've been reducing the amounts of supplements I take and giving any ones that remain some real scrutiny.

1
77877f762c40637911396daa19b53094

(78467)

on July 01, 2011
at 05:33 PM

Recently started eating about 6 raw egg yolks per day.

A968087cc1dd66d480749c02e4619ef4

(20436)

on July 01, 2011
at 05:55 PM

Gonna look like Sly Stallone soon!

0dbd7154d909b97fe774d1655754f195

(16131)

on July 01, 2011
at 07:45 PM

In potato juice scramble by any chance? I am going to try that. I'll let you know how it turns out.

77877f762c40637911396daa19b53094

(78467)

on July 01, 2011
at 07:50 PM

Yes, meredith, I am very curious to hear about your results of the potato juice scramble. That is fascinating stuff.

77877f762c40637911396daa19b53094

(78467)

on July 01, 2011
at 07:52 PM

Sly Stallone, who would want to look like him when you could look like Chris Kresser? ;)

0
0dbd7154d909b97fe774d1655754f195

(16131)

on July 01, 2011
at 04:29 PM

0dbd7154d909b97fe774d1655754f195

(16131)

on July 02, 2011
at 12:09 AM

I realize I should have made this a comment rather than an answer.

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