1

votes

Which Vitamin D, alfacalcidol or cholecalciferol (D3)?

Answered on August 19, 2014
Created September 02, 2012 at 11:16 AM

Hi,

I already knew about cholecalciferol (D3) but never heard about alfacalcidol? Few days ago, one of my friends is prescribed with alfacalcidol by his doctor. I did some research on it and found it better than D3 because it bypasses kidney.

Does anyone know about it?

0d7be15fd1a76c7a713b0e2e75381e75

(307)

on November 08, 2012
at 04:57 PM

Sounds nice in theory; I am also curious - any anecdotal experience?

0d7be15fd1a76c7a713b0e2e75381e75

(307)

on November 08, 2012
at 04:57 PM

Sounds nice in theory; I am also curious - any anecdotal experience?

F67aacf05efaf4393fa28283dd880bd5

(45)

on September 03, 2012
at 05:43 AM

So if Alfacalcidol is recommended, how it has been missed by Paleo gurus or is this new?

43f469552cfd3be73fc88a9821b14986

on September 02, 2012
at 03:49 PM

Plus one Monte. Love the drugbank site.

F67aacf05efaf4393fa28283dd880bd5

(45)

on September 02, 2012
at 01:39 PM

Thanks for letting me know. In fact, it was typo. I meant cholecalciferol.

  • F67aacf05efaf4393fa28283dd880bd5

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5 Answers

2
6d64cd6dc98d6ab763bd03678a317964

(2177)

on September 02, 2012
at 01:47 PM

http://www.drugbank.ca/drugs/DB01436

^^^ Gotta check that out^^^ What an awesome website!

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2091

Alfacalcidol is an active metabolite of Vitamin D, which performs important functions in regulation of the calcium balance and the bone metabolism. Alfacalcidol is Vitamin D-hormone analog which is activated by the enzyme 25-hydroxylase in the liver for systemic and in osteoblasts for local D-hormone actions. It possesses a unique pattern of pleiotropic effects on, e.g. gut, bone, pararthyroids, muscle and brain. Alfacalcidol is superior to plain vitamin D (cholecalciferol) because the final kidney activation of the latter is regulated by a negative feedback mechanism.

43f469552cfd3be73fc88a9821b14986

on September 02, 2012
at 03:49 PM

Plus one Monte. Love the drugbank site.

F67aacf05efaf4393fa28283dd880bd5

(45)

on September 03, 2012
at 05:43 AM

So if Alfacalcidol is recommended, how it has been missed by Paleo gurus or is this new?

0d7be15fd1a76c7a713b0e2e75381e75

(307)

on November 08, 2012
at 04:57 PM

Sounds nice in theory; I am also curious - any anecdotal experience?

0
B682c9b0d3af2760bae8deaf59dedf3f

on November 08, 2012
at 09:34 AM

Alfacalcidol is a type of vitamin D used to treat a number of conditions such as osteomalacia (rickets), familial hypophosphatemia, hypoparathyroidism, osteodystrophy, vitamin D deficiency, and so on. Also, this medication is used to increase the levels of vitamin D, calcium, and phosphate in the body. It belongs to a group of medicines called vitamin D analogues.

0
F67aacf05efaf4393fa28283dd880bd5

on September 02, 2012
at 09:49 PM

I never heard about Alfacalcidol. How Paleo gurus missed it? Is this new to supplements world?

0
43f469552cfd3be73fc88a9821b14986

on September 02, 2012
at 03:48 PM

Plus one Monte. Love the drugbank site.

0
E8bf28bd28f5be7c34d4a1a97e7c1353

(253)

on September 02, 2012
at 01:23 PM

D3 is cholecalciferol, not calcitriol, which is the more active form. Read more, mid-way down the page: http://suppversity.blogspot.ca/2012/09/on-short-notice-250-more-testosterone.html

F67aacf05efaf4393fa28283dd880bd5

(45)

on September 02, 2012
at 01:39 PM

Thanks for letting me know. In fact, it was typo. I meant cholecalciferol.

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