3

votes

non-linear response to vitamin D supplementation?

Answered on August 19, 2014
Created February 09, 2011 at 10:06 AM

i have supplemented vitamin D3 for around 1.5 years now. the first 12 months on ~10'000IU/d not much happened - my blood level always lingered around 60nmol (24ng).

now, suddenly, within the last 6 months (while still on 10kIU), my level jumped to 277nmol (110ng)! dr. davis also did a blog post about this phenomenon: http://heartscanblog.blogspot.com/2011/01/topping-up-your-vitamin-d-tank.html

Q: has anyone here experienced the same weird "hockey stick" phenomenon while supplementing with D3? what were your blood levels (dosage, before, after)? could you identify any clear factors that may have influenced/caused this jump? maybe adding vitamin A, K, or Ca/Mg? or maybe the villi tips (where the vitamin D receptors are located) just healed from going gluten free?

5f0158c23fcb5636e57b4ce097784da0

(1386)

on March 01, 2011
at 05:02 PM

yep, curious to see your result :) i also previously tried to get as much sun as possible (like 3x1h week during summer) ans the result was exactly ZERO. i was pretty surprised about that to be honest. maybe a smog thing in cities?

5f0158c23fcb5636e57b4ce097784da0

(1386)

on March 01, 2011
at 04:59 PM

no, but it's still pure speculation at this point..

82166cc32b6cf26de33b69f58fb583b1

on February 12, 2011
at 12:08 PM

Are you inclined for some particular reason to doubt Dr. Davis's "tank got full" hypothesis?

Medium avatar

(39831)

on February 09, 2011
at 06:27 PM

I agree; I posted something in the comments a while back on Davis' blog about how I suspect that body mass changes account for the reduced need for supplemental D.

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5 Answers

1
Medium avatar

on March 01, 2011
at 05:54 AM

I got about 30 minutes of sun with no shirt all summer near solar noon and I've been taking 5000IU since October or so. I just had blood drawn today for vitamin D among other things, so I'll report back with the result as soon as I get it.

5f0158c23fcb5636e57b4ce097784da0

(1386)

on March 01, 2011
at 05:02 PM

yep, curious to see your result :) i also previously tried to get as much sun as possible (like 3x1h week during summer) ans the result was exactly ZERO. i was pretty surprised about that to be honest. maybe a smog thing in cities?

1
8f4ff12a53a98f3b5814cfe242de0daa

(1075)

on March 01, 2011
at 05:02 AM

It might be worth noting that 10k IU / day is considered the absolute upper limit on safe dosage, and presumes no sun at all.

4k IU / day was the highest number I've seen recommended by a nutrition research institute (the study for it came out last week).

0
415ce5b8f88f4d762fa946f9f43d94b6

(564)

on February 23, 2011
at 07:29 PM

I started taking 10k IU about 6 months ago. I didn't have an opportunity to get baseline bloodwork done when I started, but I just got tested at 120ng/ml. (I also lost about 45 pounds in that time.) Since my "tank" seems to be full and the sun is starting to come out I'm going to stop supplementing and see where my levels are 6 months from now.

0
1f96ce108240f19345c05704c7709dad

(1061)

on February 23, 2011
at 05:59 PM

I saw almost the same thing - using the same amount of D3, and seeing my blood level jump to about 260.

I think Dr Davis is right about the tank getting full, and that the other commenters are right about fat loss affecting the storage capacity - reducing it, and driving up the blood level.

0
C1c86f42410cd4788bd9c5cf801dcd8f

(2246)

on February 09, 2011
at 11:34 AM

Vitamin D is stored in your fat cells, so if you have lost any weight it could have effected your Vitamin D levels.

If you keep taking Vitamin D then your ability to store it just fills up, it would make sence to end up taking a maintance dose after that. Larger people normally are required to take more vitamin D to raise then their levels then a smaller person would.

Medium avatar

(39831)

on February 09, 2011
at 06:27 PM

I agree; I posted something in the comments a while back on Davis' blog about how I suspect that body mass changes account for the reduced need for supplemental D.

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