3

votes

Will there always be a niacin flush?

Answered on August 19, 2014
Created July 12, 2011 at 12:06 PM

I used to be vegan. When I started to eat tons of meat again, my face turned all red. I read it was the so-called "niacin flush". Now I don't get a red face anymore, and I even supplement niacin (50mg 2x/day). Does that mean that supplement isn't working, or does it mean my body got used to the niacin?

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 10:47 PM

I couldn't agree more.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 08, 2012
at 02:13 PM

I mean up to 1 g, I personally take 200 mg. People are more willing to accept that a drug, which has often no biological function in the body, will heal while a vitamin, which has important functions in the body, is not accepted as therapeutic. Insane.

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:53 AM

Correct. However, I am not sure its completely useless. I thought it just doesn't work for some stuff regular niacin does, like HDL boosting.

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:52 AM

Its taken to rise HDL.

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:44 AM

@Korion - I am not back, just passing by from time to time to keep mods busy :)

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:43 AM

Yes, amazingly interesting. The point of orthomolecular medicine is just that - understanding that there are substances that are therapeutic and behave more like food then like drug. 1g per day is probably way to much for healthy people. Its close to therapeutic dose of statin + niacin therapy for instance.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:52 PM

really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;) And she had stomach ache the following days. Nevertheless, high doses seem to be non-toxic in most patients. Up to 1g used daily may be a safe and sufficient dose for people without serious illness.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:52 PM

healthy really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;) And she had stomach ache the following days. Nevertheless, high doses seem to be non-toxic in most patients. Up to 1g used daily may be a safe and sufficient dose for people without serious illness.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:51 PM

really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;) And she had stomach ache the following days. Nevertheless, high doses seem to be non-toxic in most patients. Up to 1g used daily may be a safe and sufficient dose for healthy people.

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on January 07, 2012
at 07:49 PM

100g ??? Glad you're back btw

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:46 PM

really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;)

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:24 PM

no-flush niacin is toxic and has a completely different effect than niacin, so you can't call it niacin. Just another way a great vitamin is hijacked by the industry.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:24 PM

no-flush niacin is toxic and has a completely different effect than niacin, so you can't call it niacin. Just another way a great vitamin is hijack by the industry.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:24 PM

no-flush niacin is toxic and has a completely different effect than niacon, so you can't call it niacin. Just another way a great vitamin is hijack by the industry.

77877f762c40637911396daa19b53094

(78467)

on January 07, 2012
at 06:31 PM

Immediate-release is non-toxic. There were scizopherinic kids taking 100g per day as revenge without ill effects. http://orthomolecular.org/library/jom/2003/pdf/2003-v18n0304-p144.pdf

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on October 27, 2011
at 05:02 AM

I totally agree, that's why I take normal niacin. I don't have that flush anymore.

3c23be3d6555cc56ed3be26b9de4e4ac

(10)

on October 26, 2011
at 11:25 PM

no flush is worthless

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on July 27, 2011
at 01:24 AM

Well, maybe not OD, but bordering the other side effect stage like liver damage,

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on July 27, 2011
at 01:21 AM

2 grams is borderline OD'ing on it. Not sure why uberbulldog's taking it, but I've seen some talk about people that are borderline diabetic using it at high doses to help with insulin sensitivity. Other main thing is high cholesterol, but not usually at those doses, and paleo thinking is not as concerned with high cholesterol. We'll have to see what he says.

1da74185531d6d4c7182fb9ee417f97f

(10904)

on July 26, 2011
at 06:37 PM

Why would one take such a high dose? I'm honestly curious. Is it to quickly correct a deficiency or does the high dose work on something specific?

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on July 18, 2011
at 03:33 PM

I actually have that, but I heard it doesn't work as well. Besides, I love the flush :), it means I'm healing.

9f933fedd259b97a5369c3ee5dae3151

(341)

on July 12, 2011
at 01:03 PM

Wow, is that daily?

667f6c030b0245d71d8ef50c72b097dc

(15976)

on July 12, 2011
at 12:14 PM

I have no idea but I take supplemental beta-alanine and it gives a tingly sensation that people say is similar to "niacin flush."

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6 Answers

2
Db3ba0e6357f76290a9ddd85aa86ed77

on October 26, 2011
at 10:32 PM

If it is no flush niacin, you will experience no side effects anyway. However, in my opinion no flush niacin is a big scam. The benefits associated with niacin flushing only occur when you take in 'normal' niacin, because this type of niacin makes your veins a little wider. This also causes the nasty side effects, but is necessary to endure.

It could also be the case that your body got used to niacin overdosing. 100 mg a day isn't really that much if you compare it to the niacin supplements containing 3000 mg.

My source for this information: niacin flush

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on October 27, 2011
at 05:02 AM

I totally agree, that's why I take normal niacin. I don't have that flush anymore.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:24 PM

no-flush niacin is toxic and has a completely different effect than niacin, so you can't call it niacin. Just another way a great vitamin is hijacked by the industry.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:24 PM

no-flush niacin is toxic and has a completely different effect than niacon, so you can't call it niacin. Just another way a great vitamin is hijack by the industry.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:24 PM

no-flush niacin is toxic and has a completely different effect than niacin, so you can't call it niacin. Just another way a great vitamin is hijack by the industry.

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:53 AM

Correct. However, I am not sure its completely useless. I thought it just doesn't work for some stuff regular niacin does, like HDL boosting.

2
E5a41bcb2819c818cc0d92489e7c35f2

on July 12, 2011
at 12:28 PM

I can't cite the science behind this, but to my understanding the body adjusts to niacin and doesn't get the flush after a pretty short while. I know a number of people who've done a purification program that includes taking VERY high doses of niacin (starting at 100 mg and working up to more than 5,000 mg a day at the end) and most of them only got the flush briefly when sharply stepping up their dosage.

1
7e935ed81bd2203bcbf8560db2ac0030

(128)

on January 07, 2012
at 06:26 PM

Time-release niacin is dangerous to the liver. Go ceck it out--all of those reported cases of liver damage from niacin for cholestrol control happened with the slow release variety.

The liver can cope with megadoses of niacin. What is harmful is to bathe the liver in niacin on an ongoing basis.

Oregon State University's Linus Pauling Institute notes: " Hepatitis has been observed with timed-release nicotinic acid at dosages as little as 500 mg/day for two months, although almost all reports of severe hepatitis have been associated with the timed-release form of nicotinic acid at doses of 3 to 9 grams per day used to treat high cholesterol for months or years (8). Immediate-release (crystalline) nicotinic acid appears to be less toxic to the liver than extended release forms. Immediate-release nicotinic acid is often used at higher doses than timed-release forms, and severe liver toxicity has occurred in individuals who substituted timed-release niacin for immediate-release niacin at equivalent doses (33)."

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on January 07, 2012
at 07:49 PM

100g ??? Glad you're back btw

77877f762c40637911396daa19b53094

(78467)

on January 07, 2012
at 06:31 PM

Immediate-release is non-toxic. There were scizopherinic kids taking 100g per day as revenge without ill effects. http://orthomolecular.org/library/jom/2003/pdf/2003-v18n0304-p144.pdf

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:44 AM

@Korion - I am not back, just passing by from time to time to keep mods busy :)

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:46 PM

really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;)

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 10:47 PM

I couldn't agree more.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:52 PM

really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;) And she had stomach ache the following days. Nevertheless, high doses seem to be non-toxic in most patients. Up to 1g used daily may be a safe and sufficient dose for people without serious illness.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:51 PM

really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;) And she had stomach ache the following days. Nevertheless, high doses seem to be non-toxic in most patients. Up to 1g used daily may be a safe and sufficient dose for healthy people.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 07, 2012
at 07:52 PM

healthy really interesting. However, the girl taking 100g was ingesting 200 tablets because she was angry at her mother ;) And she had stomach ache the following days. Nevertheless, high doses seem to be non-toxic in most patients. Up to 1g used daily may be a safe and sufficient dose for people without serious illness.

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:43 AM

Yes, amazingly interesting. The point of orthomolecular medicine is just that - understanding that there are substances that are therapeutic and behave more like food then like drug. 1g per day is probably way to much for healthy people. Its close to therapeutic dose of statin + niacin therapy for instance.

Ec7cb2a7a68655954a01f03e95be1383

(1453)

on January 08, 2012
at 02:13 PM

I mean up to 1 g, I personally take 200 mg. People are more willing to accept that a drug, which has often no biological function in the body, will heal while a vitamin, which has important functions in the body, is not accepted as therapeutic. Insane.

1
54ad84a1bf76ddf930d6186048cf6d3d

on July 12, 2011
at 02:55 PM

Vitamin Shoppe and GNC sell "no-flush" niacin ... it works as advertised!

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on July 18, 2011
at 03:33 PM

I actually have that, but I heard it doesn't work as well. Besides, I love the flush :), it means I'm healing.

3c23be3d6555cc56ed3be26b9de4e4ac

(10)

on October 26, 2011
at 11:25 PM

no flush is worthless

1
3899bf80f345c760036a7fcc490fd727

on July 12, 2011
at 01:15 PM

I take 1,000 mg Slo-Niacin every night at bedtime (worked up to this amount). If I stay asleep all night, I don't notice a flush. However, if I do happen to wake up, that flush is always waiting around for me, all hot and itchy. :( It pays to stay asleep.

1
Medium avatar

on July 12, 2011
at 12:29 PM

I take 2 grams of slo-niacin and the flush is minimal. Of course I built up slowly to this level.

9f933fedd259b97a5369c3ee5dae3151

(341)

on July 12, 2011
at 01:03 PM

Wow, is that daily?

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on July 27, 2011
at 01:21 AM

2 grams is borderline OD'ing on it. Not sure why uberbulldog's taking it, but I've seen some talk about people that are borderline diabetic using it at high doses to help with insulin sensitivity. Other main thing is high cholesterol, but not usually at those doses, and paleo thinking is not as concerned with high cholesterol. We'll have to see what he says.

1da74185531d6d4c7182fb9ee417f97f

(10904)

on July 26, 2011
at 06:37 PM

Why would one take such a high dose? I'm honestly curious. Is it to quickly correct a deficiency or does the high dose work on something specific?

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on July 27, 2011
at 01:24 AM

Well, maybe not OD, but bordering the other side effect stage like liver damage,

77877f762c40637911396daa19b53094

(78467)

on January 08, 2012
at 12:52 AM

Its taken to rise HDL.

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