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Iodine supresses thyroid?

Commented on December 24, 2013
Created December 02, 2013 at 11:41 PM

I've read both that Iodine fixes hypothyroid in large doses, and that it can cause hypothyroid in large doses by supressing thyroid function.

What's correct?

Personally I've cycled on and off Iodine many times and always seem to feel better with more consistent energy when I'm on it.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on December 24, 2013
at 04:25 PM

A bottle of Lugol's has enough elemental iodine to kill you. Be careful!

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 24, 2013
at 02:41 PM

It's typically a paleo diet with extra restrictions. zero dairy (no butter either, possibly no ghee as well), no eggs, no nightshades. Depending on what allergies you may have, removing those is required too. (i.e. almonds if you're allergic to them, etc.) Starches are usually ok, but all vegetables contain proteins, and it's the proteins we tend to be allergic to - so you may find some that cause trouble.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on December 24, 2013
at 01:09 AM

"You should always take iodine with selenium" worth emphasising that point...aim to be replete in both iodine and selenium, both adhere to the U shaped curved mentioned.

A4c5aefc339e2bfd584b4c76ba500b41

on December 23, 2013
at 11:24 PM

Interesting. Is there ever an issue with deficiency or too much of L-tyrosine or its precursors?

A4c5aefc339e2bfd584b4c76ba500b41

on December 23, 2013
at 11:18 PM

I've read something about iodine maybe not being such a good idea with Hashimoto's (something about it provoking more of an autoimmune response?) but can't recall where. Any ideas why that might be? Is it possible one might want to be careful supplementing iodine with specific thyroid disorders if this is true?

Medium avatar

(15)

on December 23, 2013
at 05:11 PM

The only thing that is bullshit, is what you wrote Gastronomer. Be very careful about the advice of this member!

D05f3050dc3d973b8b81a876202fa99a

(1533)

on December 23, 2013
at 02:14 PM

Yes definitely mg. not sure how you would get a gram of it lol.

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 23, 2013
at 01:20 PM

Same wikipedia link above: "iodine has been used to manage Graves' disease." So excess iodine can also suppress the thyroid, and even be used to manage Graves disease, hence U-shape curve. Please stop talking nonsense, if people follow your theories, they may get injured.

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 23, 2013
at 01:16 PM

From the same "Normally, the thyroid gland can regulate thyroid hormone synthesis and secretion in the presence of excessive amounts of iodine in the body." Next it mentions the "Wolff-Chaikoff effect which is "is a reduction in thyroid hormone levels caused by ingestion of a large amount of iodine."

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 23, 2013
at 01:13 PM

From another "Rarely, it is induced by local inflammation of the thyroid gland (thyroiditis) or excessive intake of or exposure to iodine"

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 23, 2013
at 12:58 PM

The problem is that if you have an autoimmune condition, you want to shut off your thyroid until you can get the antibodies down (via a strict paleo AI diet). If you ramp up your thyroid hormone production, the autoimmune cells will attack your thyroid even harder - since ironically, thyroid hormones play a part in the immune system. So supplementing blindly with iodine when you're hypothyroid can be a very bad idea.

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 23, 2013
at 12:53 PM

from one of your links: "Iodine-induced hyperthyroidism is usually seen in patients who already have an underlying abnormal thyroid gland." <- i.e. doesn't just happen with excess iodine.

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 23, 2013
at 12:45 PM

Yes, thyroids need iodine, selenium and L-tyrosine to make T3/T4.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on December 23, 2013
at 02:34 AM

Mario Renato Iwakura (a hashimoto???s thyroiditis patient) posted two articles on hashimoto???s thyroiditis & covered supplementing with iodine and selenium over on the Jaminet site, here & here

i read these articles a long time ago now, but from memory, selenium is 'the key' ie. supplementing with iodine is risky if you are selenium deficient (or something like that)

543a65b3004bf5a51974fbdd60d666bb

(4493)

on December 23, 2013
at 02:25 AM

"somewhere around 4-12 grams for loading?"...a typo i'm guessing...milligrams (not grams).

1 drop 2% lugol's =~2.5 mg iodine (1 drop 5% lugol's =~6.25 mg iodine)

D05f3050dc3d973b8b81a876202fa99a

(1533)

on December 23, 2013
at 01:53 AM

Does selenium play a role here?

D05f3050dc3d973b8b81a876202fa99a

(1533)

on December 23, 2013
at 01:52 AM

What about in combination with selenium as Chris Kresser has discussed?

Be157308a0438e382b88d9db4c12ab30

on December 22, 2013
at 08:38 PM

Right here: http://www.ncbi.nlm.nih.gov/m/pubmed/12448333/?i=5&from=/11396708/related here http://www.medicinenet.com/script/main/mobileart.asp?articlekey=391&page=4 here http://en.wikipedia.org/wiki/Hyperthyroidism#Causes here http://surgery.med.umich.edu/general/endocrine/patient/conditions/thyroid/hyperthyroidism.shtml and here http://www.hindawi.com/crim/endocrinology/2013/792745/

310175c4779bfa3a131ceabf03809169

on December 22, 2013
at 07:18 PM

As a side note, I speak from experience. I have had Hashimoto's for 15+ years. I increased my iodine supplementation thinking that it would help my thyroid. After almost destroying my thyroid gland, and a full year of research, I discovered that iodine was the WRONG thing to be taking with an autoimmune disease. Lots of medical research on this subject. But you have to search for auto-immune + iodine supplementation, not just hypothyroid + iodine.

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 22, 2013
at 05:20 PM

http://ajcn.nutrition.org/content/early/2011/12/26/ajcn.111.028001.abstract

"subclinical hypothyroidism appeared in the participants who took the 400-??g I supplement, which provided a total iodine intake of ???800 ??g/d. Thus, we caution against a total daily iodine intake that exceeds 800 ??g/d in China and recommend further research to determine a safe daily upper limit."

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 22, 2013
at 05:16 PM

And which orifice did you pull that out of?

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 22, 2013
at 05:04 PM

Hard to tel, it depends on the person. USDA requirements are just for preventing goiters and cretinism.

The best test you can do is to take zero supplemental iodine, then to paint a square of lugol's solution on your skin, let it dry and see how long before it vanishes. If it's far less than 24h, you're deficient, so take some more; the quicker it vanishes, the more deficient you are. see:

http://ihcfl.com/uploads/3/0/9/7/3097145/iodine_paint_patch_test.pdf

D05f3050dc3d973b8b81a876202fa99a

(1533)

on December 22, 2013
at 04:37 PM

Interesting, so somewhere around 4-12 mg for loading? How about maintenance? What are the downsides of taking too much & where would that start?

[edit by Matt11: mg, not grams!]

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3 Answers

0
310175c4779bfa3a131ceabf03809169

on December 22, 2013
at 07:15 PM

WRONG! It totally depends on WHY your thyroid isn't working! If you simply have a sluggish thyroid, resulting in a hypothyroid condition, than yes you can supplement with iodine. HOWEVER, if you have an AUTOIMMUNE disease such as Hashimotos, then NEVER supplement with iodine. In autoimmune conditions that attack your thyroid gland, additional iodine will make your disease WORSE. Get diagnosed as to why your thyroid isn't working.

310175c4779bfa3a131ceabf03809169

on December 22, 2013
at 07:18 PM

As a side note, I speak from experience. I have had Hashimoto's for 15+ years. I increased my iodine supplementation thinking that it would help my thyroid. After almost destroying my thyroid gland, and a full year of research, I discovered that iodine was the WRONG thing to be taking with an autoimmune disease. Lots of medical research on this subject. But you have to search for auto-immune + iodine supplementation, not just hypothyroid + iodine.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on December 23, 2013
at 02:34 AM

Mario Renato Iwakura (a hashimoto???s thyroiditis patient) posted two articles on hashimoto???s thyroiditis & covered supplementing with iodine and selenium over on the Jaminet site, here & here

i read these articles a long time ago now, but from memory, selenium is 'the key' ie. supplementing with iodine is risky if you are selenium deficient (or something like that)

0
Be157308a0438e382b88d9db4c12ab30

on December 22, 2013
at 05:02 PM

Increased iodine can only increase thyroid function, not decrease it. THERE IS NO U-SHAPED CURVE association between iodide and thyroid function, that is pure bullshit. Too little iodine causes HYPOthyroidism, too much causes HYPERthyroidism, these two conditions are complete opposites, it's as simple as that. If you consume normal, plain old iodized table salt you have nothing to worry about.

Medium avatar

(15)

on December 23, 2013
at 05:11 PM

The only thing that is bullshit, is what you wrote Gastronomer. Be very careful about the advice of this member!

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 22, 2013
at 05:20 PM

http://ajcn.nutrition.org/content/early/2011/12/26/ajcn.111.028001.abstract

"subclinical hypothyroidism appeared in the participants who took the 400-??g I supplement, which provided a total iodine intake of ???800 ??g/d. Thus, we caution against a total daily iodine intake that exceeds 800 ??g/d in China and recommend further research to determine a safe daily upper limit."

96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 22, 2013
at 05:16 PM

And which orifice did you pull that out of?

0
96440612cf0fcf366bf5ad8f776fca84

(19413)

on December 03, 2013
at 04:44 PM

Both are correct.

Most nutrients have a U-shaped curved. If you're at the ends, you'll either be deficient, or overdosing, (i.e. a total absence of iodine on one end, or far too much at the other end). The middle of the U is where you want to be, that's where the nutrient provides the most benefit and is optimal.

Turns out that iodine need depends on your body's individual need. The USRDA is far too low to be optimal, and is only the absolute minimum needed to avoid goiters - even then with the "War on Salt" and people switching to seasalt over iodized salt, you could easily get too little.

Modern life is full of halogens (chlorine, bromides, fire retardants in furniture, etc) and other endocrine system disruptors that get mistaken for iodine by the receptors and block iodine from entering. So we actually need even more than in the past.

If you take a large load of iodine to displace the halogens, it may work (and you may experience symptomps such as diarhea), but if you continue, you may cause problems.

Something like 2-5 drops of Lugol's Solution at 2% is plenty for loading. Don't do that every day.

You should always take iodine with selenium as both minerals are needed to produce the thyroid hormones.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on December 24, 2013
at 01:09 AM

"You should always take iodine with selenium" worth emphasising that point...aim to be replete in both iodine and selenium, both adhere to the U shaped curved mentioned.

D05f3050dc3d973b8b81a876202fa99a

(1533)

on December 22, 2013
at 04:37 PM

Interesting, so somewhere around 4-12 mg for loading? How about maintenance? What are the downsides of taking too much & where would that start?

[edit by Matt11: mg, not grams!]

A4c5aefc339e2bfd584b4c76ba500b41

on December 23, 2013
at 11:18 PM

I've read something about iodine maybe not being such a good idea with Hashimoto's (something about it provoking more of an autoimmune response?) but can't recall where. Any ideas why that might be? Is it possible one might want to be careful supplementing iodine with specific thyroid disorders if this is true?

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