6

votes

Thoughts on Sam-E

Answered on September 12, 2014
Created March 01, 2011 at 7:54 PM

Does anyone have significant firsthand experience with Sam-E? I am considering trying it for depressive tendencies, anxiety and extreme PMS mood swings, as I understand Sam-E can help with each of these issues.

I am not interested in prescription drugs for any of these afflictions, since they are not out of control for me, but they are indeed consistently present in varying degrees and rather than ignore them simply because I am fairly adept at managing them, I would like to assuage them if possible.

Has anyone who has used Sam-E been very successful with it? Or perhaps suffered adverse side effects? I would love to hear the thoughts of the much esteemed Paleo community on Sam-E. :)

Thank you!

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:58 AM

The vivid dreams from 5htp are typically just for the first 1-3 nights. DAC did you take it every night and did you have vivid dreams the whole time you took it? If so, that is very unusual.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:55 AM

Not helpful Bill and not answering the Q at all. All the things you list are not going to make a dent into the issues CheshyCat is describing. SamE is a supplement and we don't have a problem with that. If you want to call it a drug that's your choice. Maybe her underlying issue is with Neurotransmitters and diet etc can help but may not be enough.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:52 AM

Very interesting Helen. How did you figure this out?

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:51 AM

FYI Li Orotate (and even the Rx form of Li) is just as helpful for depression as it is for Bipolar... although it usually is not used for this purpose except as an adjunct therapy to an antidepressant. Too bad as the research on that is clear (but its not Li Oro that is researched rather than Rx form.)

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:44 AM

Dan - I totally agree. I think its rare that "they" use that much but they have. 600 was a lot. I took it divided into three doses 100-100-300. At the time I was quite depressed and lots of issues. It helped a lot and oddly I had the opposite effect at that dose - it made me want to eat and eat and eat... weird. I have read about that but most people have decreased appetite on it for sue.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:40 AM

Capsules. We use Pure Encapsulations but Im sure there are other decent brands too. For osteo.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 03:28 AM

For the record, I think I would trip balls if I took 3000mg of 5htp.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 03:27 AM

WOW!!! 3000mg sounds really really intense! 600mg a day also seems like a *lot*. I take 50mg a day. I used to take 100mg, sometimes 200mg a day. I find that I can definitely overdo it-loss of appetite, loss of connection with certain emotions... 50mg makes a big difference with me, too. I am more at peace on 5htp, that's for sure. But I do feel disconnected with my baser, passionate, even animalistic side. It's a trade off. 5htp is an invaluable tool for low-carbers too.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 03:22 AM

Injections or in supplements? For rheumatoid or osteo?

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 02:40 AM

Dan W I dont know about SamE for joints but I can tell you that I have had really good luck with Hyaluronic Acid for joints.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 01:48 AM

I think its always wise to use the lowest possible effective dose of anything. Then again, higher doses are sometimes needed. It depends how low your serotonin is to begin with. Doses as high as 3000mg per day are sometimes used according to NeuroAssist - but that is extreme. I have been on 600mg a day. I now take 200mg. What is your concern Dan?

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 01:46 AM

Also, does anyone have significant firsthand experience with Sam-E for *joint* problems?

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 01:38 AM

Rhodiola Rosea is another herb that is pretty good, in a similar way.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 01:37 AM

5htp IS effective. Use cautiously and moderately.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32556)

on August 07, 2012
at 09:28 PM

Without sufficient D, your body cannot balance your hormones.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32556)

on August 07, 2012
at 09:26 PM

Get your D level checked. You can buy a home test kit from www.vitamindcouncil.org. 60-80 ng/ml is the blood level I would aim for in your case.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 07, 2012
at 09:05 PM

Good info here Sara.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 07, 2012
at 09:04 PM

RIGHT! Thanks scorp2780. I also take Li Orotate as depression is an issue for me and my blood level was very very very low.

1a68c71d62aa058a86c83c5bb0c28650

(150)

on January 30, 2012
at 04:38 PM

It sounds like you may have bipolar harms.20 b/c it made you manic. Consider lithium orotate.

1a68c71d62aa058a86c83c5bb0c28650

(150)

on January 30, 2012
at 04:37 PM

Great post by qualia. You may also want to look at Lithium Orotate as another mood supplement.

1fc9c11cf23b2f62ac78979de933ad83

(2435)

on April 27, 2011
at 05:35 PM

I always assumed it was a hormonal thing, the random occasional rage. I'm gonna have to look into niacin, now...

F52b51135f2c47eb46c986fdc9760b9b

(180)

on March 12, 2011
at 04:41 AM

took a couple different brands, don't remember which. I know they say you shouldn't use SAM-e if you are bi-polar, and while I'm not bi-polar I did have some other psych issues, so maybe it was just a bad match for me personally?

6a4fd73b4ae4761eefec8e0d38e6f224

(1008)

on March 02, 2011
at 10:22 PM

There's no time like the present; it's springtime! It's so easy to work it into your day - even 10 or 15 minutes at a time. Pick the sunny side of the street and leave your shades in your purse. Consider it medicine. (Bonus: A walk = more exercise.)

Medium avatar

(310)

on March 02, 2011
at 09:48 PM

Interesting. Thanks for sharing that, though I'm sorry to hear you had such a bad experience. It's useful to know that there can be adverse side effects.

Medium avatar

(310)

on March 02, 2011
at 09:46 PM

Really? WOW! Who would have thought? Thanks!

Medium avatar

(310)

on March 02, 2011
at 09:46 PM

THANK YOU! These recommendations are great. I actually *just* improved my supplementation with cod liver oil and adaptogens, so maybe I should wait before jumping into Sam-E (new realization). If they don't suffice though, I'll get the Jarrow version you mentioned.

Medium avatar

(310)

on March 02, 2011
at 09:43 PM

No, I don't experience that, but thank you, Helen! I'm glad to hear you're doing better. :)

Medium avatar

(310)

on March 02, 2011
at 09:43 PM

I've looked into all of these things intensively at various points of life. I think to a degree some of us really are predisposed at the chemical level to depression/anxiety, though I agree, medication is medication.

Medium avatar

(310)

on March 02, 2011
at 09:42 PM

I take D supplements. I definitely get sufficient fat and cholesterol from my yummy Paleo diet. :)

Medium avatar

(310)

on March 02, 2011
at 09:41 PM

Thanks DAC. I am NOT getting plenty of sunlight, as it happens.

5f0158c23fcb5636e57b4ce097784da0

(1386)

on March 02, 2011
at 04:31 PM

which brand did you take? quality is very important when taking SAMe - there are huge differences, and some of it is cheap crap.

1acc4ee9381d9a8d998b59915b3f997e

(2099)

on March 01, 2011
at 11:55 PM

Oh, you're welcome, Kaz :)

74f5d2ff6567edd456d31dfb9b92af61

(5227)

on March 01, 2011
at 11:24 PM

You always have such interesting things to share! Goodness, the more I learn, the more I think my vegetarian diet was out to get me. I'm going to research this further. Thank you, Helen! :)

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16 Answers

7
5f0158c23fcb5636e57b4ce097784da0

(1386)

on March 02, 2011
at 05:22 PM

SAMe is one of the most impressive supplements i have ever used with regards to enhancing mood (and i have tried pretty much every supplement). the effect is of the highest possible quality and feels 100% "real" - like if your brain would take a deep breath, and say: "aah, THIS IS THE REAL ME!" - in contrast to many other synthetic anti-depressants, like SSRIs for example. really very impressive stuff, IF your nutrient status and brain biochemistry allows for it to work properly (meaning, if you're having a methylation problem for example). it may very well be that your mood swings are caused by one or more deficiencies (usual candidates are B12, folate, B6 (P5P), D, DHA/EPA, magnesium, iron, etc). so you def. first need to be sure to not simply be malnutritioned. start with taking sublingual methyl-B12 to see how your B12 status is for example.

the quality of the SAMe you take is also very important. there is cheap stuff, which only has 50% of the beneficial/active component in it, and there is "purified" SAMe, which is like 80% or so of the active S-isomer. i recommend you try something like this, from jarrows for example: http://is.gd/wmr98V take 400mg at least 20min before breakfast on empty stomach, and if you don't feel anything (the effect can be slow and subtle at first), take another one in the afternoon between meals.

the only negatives i have found with SAMe is the rel. high price, and the fact that the effect seems to fade away after a few weeks (again, this is probably very individual). so you may need to take a break after a few weeks to make it work again or fill up the other nutrients that may be laking. a much cheaper alternative to SAMe is TMG (http://is.gd/iF3YSc), which works in a similar way, but usually is not quite as effective or impressive. other alternatives for mood enhancement would be St. Johns Wort, Phosphatidyl-Serine, P5P (B6), Inositol, 5-HTP, DHEA, Kava Kava, Ginseng, etc. depending on what your exact needs are.

Medium avatar

(310)

on March 02, 2011
at 09:46 PM

THANK YOU! These recommendations are great. I actually *just* improved my supplementation with cod liver oil and adaptogens, so maybe I should wait before jumping into Sam-E (new realization). If they don't suffice though, I'll get the Jarrow version you mentioned.

1a68c71d62aa058a86c83c5bb0c28650

(150)

on January 30, 2012
at 04:37 PM

Great post by qualia. You may also want to look at Lithium Orotate as another mood supplement.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 07, 2012
at 09:04 PM

RIGHT! Thanks scorp2780. I also take Li Orotate as depression is an issue for me and my blood level was very very very low.

4
F52b51135f2c47eb46c986fdc9760b9b

on March 02, 2011
at 03:53 PM

I had a HORRIBLE experience with sam-e. It improved my mood for a short while (like a week) but then my mood quickly went from nicely improved to really manic, compulsive, aggressive...like I was to the point of trying to start fights with strangers at the store and stuff, which is what finally made me quit. It also really messed with my digestion. I think it's because of the enteric coating, which can only be digested in the intestines, but what happened to me is when the pill was going through me the rest of my digestion completely stopped.

And a third problem it caused--and this is the most serious one--is it significantly weakened my hip joints. Sam-e is supposed to improve joint strength, and at first it really did, and my hip joints felt stronger than they had in years. But when I stopped taking Sam-e my hips quickly went from stronger than ever before to weaker than ever before, I guess because my body stopped making it's own Sam-e, and got reliant on the pill? Anyway, it's been two years since i stopped and I still have problems with hip pain. It really feels like the whole area is permanently damaged! I really regret taking it, becuase i'm only 32, but I feel like I have the hips of an old man.

In most countries Sam-e is available only by prescription, which makes sense, because it is very powerful. All of the above problems resulted after only 3 weeks of taking it. I'm not sure why they decided to let it be sold over the counter in the U.S., where I live.

Medium avatar

(310)

on March 02, 2011
at 09:48 PM

Interesting. Thanks for sharing that, though I'm sorry to hear you had such a bad experience. It's useful to know that there can be adverse side effects.

5f0158c23fcb5636e57b4ce097784da0

(1386)

on March 02, 2011
at 04:31 PM

which brand did you take? quality is very important when taking SAMe - there are huge differences, and some of it is cheap crap.

F52b51135f2c47eb46c986fdc9760b9b

(180)

on March 12, 2011
at 04:41 AM

took a couple different brands, don't remember which. I know they say you shouldn't use SAM-e if you are bi-polar, and while I'm not bi-polar I did have some other psych issues, so maybe it was just a bad match for me personally?

1a68c71d62aa058a86c83c5bb0c28650

(150)

on January 30, 2012
at 04:38 PM

It sounds like you may have bipolar harms.20 b/c it made you manic. Consider lithium orotate.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:51 AM

FYI Li Orotate (and even the Rx form of Li) is just as helpful for depression as it is for Bipolar... although it usually is not used for this purpose except as an adjunct therapy to an antidepressant. Too bad as the research on that is clear (but its not Li Oro that is researched rather than Rx form.)

4
Medium avatar

on March 01, 2011
at 09:09 PM

What do you eat? Have you already addressed dietary deficiencies? Sufficient fat, cholesterol and vitamin D intake improves those symptoms in a lot of people. Have you had D levels checked?

Medium avatar

(310)

on March 02, 2011
at 09:42 PM

I take D supplements. I definitely get sufficient fat and cholesterol from my yummy Paleo diet. :)

Ce41c230e8c2a4295db31aec3ef4b2ab

(32556)

on August 07, 2012
at 09:28 PM

Without sufficient D, your body cannot balance your hormones.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32556)

on August 07, 2012
at 09:26 PM

Get your D level checked. You can buy a home test kit from www.vitamindcouncil.org. 60-80 ng/ml is the blood level I would aim for in your case.

2
4ef079c57d2140bba4dbf4e30240a645

on August 07, 2012
at 08:59 PM

I took it for a while and noted nothing - except less money in my account!

I suffered severe mood issues related to my cycle for years. What I had was PMDD... and you may too if you are getting depressed at the end of each cycle. It sucks.
There are many small and medium things to do for pms/pmdd and I assume you have done all or most - clean diet, exercise, sleep, decreasing stress as much as possible and blah blah blah.

The issue with pmdd is hormones. What finally, after years of suffering, helped me was getting hormones balanced. Bio-identical hormone treatment saved my life - literally.

Even if you are young, you may well have estrogen dominance (low progesterone).

In addition to the bio-identical hormone creams - I use 5htp and PharmaGaa (as needed) at the end of my cycle.
I have found 5htp to be WAY MORE EFFECTIVE then Sam-E. PharmaGaba is also great if all else has failed.

This link will help you find a doctor who knows about hormone balancing.
http://foreverhealth.com/

Good luck to you.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 01:37 AM

5htp IS effective. Use cautiously and moderately.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 03:28 AM

For the record, I think I would trip balls if I took 3000mg of 5htp.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:44 AM

Dan - I totally agree. I think its rare that "they" use that much but they have. 600 was a lot. I took it divided into three doses 100-100-300. At the time I was quite depressed and lots of issues. It helped a lot and oddly I had the opposite effect at that dose - it made me want to eat and eat and eat... weird. I have read about that but most people have decreased appetite on it for sue.

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 03:27 AM

WOW!!! 3000mg sounds really really intense! 600mg a day also seems like a *lot*. I take 50mg a day. I used to take 100mg, sometimes 200mg a day. I find that I can definitely overdo it-loss of appetite, loss of connection with certain emotions... 50mg makes a big difference with me, too. I am more at peace on 5htp, that's for sure. But I do feel disconnected with my baser, passionate, even animalistic side. It's a trade off. 5htp is an invaluable tool for low-carbers too.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 01:48 AM

I think its always wise to use the lowest possible effective dose of anything. Then again, higher doses are sometimes needed. It depends how low your serotonin is to begin with. Doses as high as 3000mg per day are sometimes used according to NeuroAssist - but that is extreme. I have been on 600mg a day. I now take 200mg. What is your concern Dan?

2
1acc4ee9381d9a8d998b59915b3f997e

(2099)

on March 01, 2011
at 09:18 PM

Do you ever experience bouts of rage over miniscule things? The reason I ask is because I was struggling with rage and depression, and it turned out to be a niacin deficiency! When I started taking 1,500mg of niacinamide per day the rage disappeared like magic, and the depression is much, much less now, too.

1fc9c11cf23b2f62ac78979de933ad83

(2435)

on April 27, 2011
at 05:35 PM

I always assumed it was a hormonal thing, the random occasional rage. I'm gonna have to look into niacin, now...

1acc4ee9381d9a8d998b59915b3f997e

(2099)

on March 01, 2011
at 11:55 PM

Oh, you're welcome, Kaz :)

74f5d2ff6567edd456d31dfb9b92af61

(5227)

on March 01, 2011
at 11:24 PM

You always have such interesting things to share! Goodness, the more I learn, the more I think my vegetarian diet was out to get me. I'm going to research this further. Thank you, Helen! :)

Medium avatar

(310)

on March 02, 2011
at 09:43 PM

No, I don't experience that, but thank you, Helen! I'm glad to hear you're doing better. :)

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:52 AM

Very interesting Helen. How did you figure this out?

2
Ef4c5b09fdccf73be575d3a0c267fdd9

(2539)

on March 01, 2011
at 09:17 PM

I would start with what you eat and then look into acupuncture, yoga, meditation, and therapy. Taking Sam-E would be the same as taking a drug. Get down to the underlying issues.

Medium avatar

(310)

on March 02, 2011
at 09:43 PM

I've looked into all of these things intensively at various points of life. I think to a degree some of us really are predisposed at the chemical level to depression/anxiety, though I agree, medication is medication.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:55 AM

Not helpful Bill and not answering the Q at all. All the things you list are not going to make a dent into the issues CheshyCat is describing. SamE is a supplement and we don't have a problem with that. If you want to call it a drug that's your choice. Maybe her underlying issue is with Neurotransmitters and diet etc can help but may not be enough.

1
7841848bd0c27c64353c583fb7971242

(7275)

on August 07, 2012
at 08:44 PM

I've been taking SAM-e for a couple weeks now and it has helped a lot. I am taking 400 mg per day, split into two doses. I take a third if I stay up late, because I feel low serotonin/withdrawal/anxiety at about 8 hours after taking it.

The reason I take it is because I am heterozygous for the MTHFR mutation and my symptoms matched all the things that SAM-e is supposed to improve.

For anyone thinking of taking it, I recommend taking methyl-B12, folate, and betaine/TMG to prevent buildup of homocysteine. I also recommend not taking niacin or niacinamide, as per this thread.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 07, 2012
at 09:05 PM

Good info here Sara.

1
1f96ce108240f19345c05704c7709dad

(1061)

on March 01, 2011
at 09:49 PM

You might check out this web page, CheshyCat - http://www.raysahelian.com/sam-e.html.

From the website - "Dozens of clinical studies have demonstrated that it helps support a positive outlook. It is able to cross the blood-brain barrier where it affects the synthesis and activation of various brain chemicals, such as neurotransmitters. SAM-e also supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation."

So, it seems that sam-e works very well for some people, and makes things worse for others. A small starting does seems appropriate (50 to 100 mg) and slowly increasing (but watch out for side effects).

Sam-e is not recommended for people with sleep issues - it makes you alert.

Sam-e is made from naturally occurring amino acids.

Your underlying issue could be a shortage of these amino acids, and sam-e may well help you balance them. It might be worth a try.

1
6a4fd73b4ae4761eefec8e0d38e6f224

(1008)

on March 01, 2011
at 08:55 PM

I haven't tried it, but I have been using another natural purported antidepressive, 5-HTP, and it does seem to "take the edge off" and also help me sleep (though it gives me some crazy vivid dreams). I assume you're already getting plenty of sunlight; that's a huge help.

Medium avatar

(310)

on March 02, 2011
at 09:41 PM

Thanks DAC. I am NOT getting plenty of sunlight, as it happens.

6a4fd73b4ae4761eefec8e0d38e6f224

(1008)

on March 02, 2011
at 10:22 PM

There's no time like the present; it's springtime! It's so easy to work it into your day - even 10 or 15 minutes at a time. Pick the sunny side of the street and leave your shades in your purse. Consider it medicine. (Bonus: A walk = more exercise.)

4ef079c57d2140bba4dbf4e30240a645

(4413)

on August 08, 2012
at 06:58 AM

The vivid dreams from 5htp are typically just for the first 1-3 nights. DAC did you take it every night and did you have vivid dreams the whole time you took it? If so, that is very unusual.

0
4f64c9f81bb0d4ee969aaf7b4a5a6f40

on August 08, 2013
at 05:57 AM

I have PMDD. Usually I feel very depressed for one or two days before my period begins each month. However, I have been on Sam-E for one month and I didn't cry or feel depressed before I got my period this month. For me Sam-E has been amazing. I would really recommend it. I have had no side effects. However, as a word of caution, Sam-E is not for bipolar people.

0
B93db352b195997eae9d141f87125548

on May 26, 2013
at 12:17 AM

After years on prescription antidepressants and awful withdrawal from them Sam-e has been a lifesaver. I tried a variety of other herbs with no success. The Natures Sunshine brand is very expensive and Jarrow and NOW didn't work. I am presently using Nature Made Same-Complete 400 mg and I love it. I feel great physically and even my sleep has improved. My depression is better controlled than its ever been before. I take 400 mg twice a day on an empty stomach. You may want to get an Herbal Compass done to see if there are other suppliments you need. Good luck !!

0
3d64682f2b7a84f8601e654a200cb3b7

(0)

on February 11, 2013
at 06:11 PM

ive been on sam e for a week and i wou??ld say it has helped my depression

0
Dde60eddeaf3d419f20030c23b7f4b85

on September 02, 2012
at 08:55 PM

My doctor recommende SAM-E a few years ago for mood enhancement. I didn't notice a difference so I stopped taking them and kept the 2 boxes I bought. Fast forward 4 years later. I had major hip pain for several years due to the statins I took for only 3 months. I started taking turmeric and that helped a lot(4800mg/day). But it didn't cure it 100%. Then one day I was cleaning out the cupboard and found the 2 boxes, 2 years expired. I googled it and saw that it helps joint pain. So not wanting to waste it I tried it. By the 4th day I noticed I felt better. I have been on them for 2 months now. The reason it didn't work the first time is that my body was low in vitamin B, a necessary component. I feel the best I have in a number of years. My knees don't hurt anymore when I climb the stairs and I can now practice Zumba dance, which I could not before. One day I took 400mg, just to try it, and I became very anxious the whole day. I backed off to 2hundred mg 2/Xday, and after a month I am only taking 200mg 1X/day. It is important to review literature on everything you take once in a while. New data comes out and that' where I found out that it doesn't work well if you are low in vitamin B. Find a doctor of integrative medicine to help you through the info and do your own research too.

0
43415e864447504fb7e659e58abdc309

on June 06, 2011
at 04:45 PM

P.S. I also have even more information about depression at my other blog and online nutritional supplement/herbal medicine store: http://www.holisticchineseherbs.com/?s=depression. If you do decide on sam-e, make sure you choose a quality sam-e supplement. These are the brands I recommend: http://www.holisticchineseherbs.com/supplements/sam-e/

0
43415e864447504fb7e659e58abdc309

on June 06, 2011
at 04:41 PM

I am a Chinese Medicine practitioner, functional medicine practitioner, Paleo for over 7 years, and former vegan who has dealt with many issues with severe depression through changing my diet and using Chinese herbal medicine. Please see the information I have on my blog about overcoming depression: http://www.superherohealthcare.com/2/category/depression/1.html

0
65430e39d7e9e9322718d016fe668051

(2944)

on March 01, 2011
at 09:11 PM

I had severe depression for 2 years (I didn't know I did until I took some screening tests online in January). My best friend keeps trying to get me to go on anti-depressants but of course I won't. About 6 weeks ago a woman had a Rescue Remedy table set up at whole foods and I was talking to her. She recommended New Chapter Holy Basil. I told her I'd taken holy basil for something else before and she said New Chapter is the best. I took her advice (whole foods does have a return policy after all) and took 2 holy basil capsules that day (along with some rescue remedy). Within a couple hours 95% or more of my depression was GONE. I highly recommend New Chapter Holy Basil. I was shocked. Usually nothing makes me feel better even short term.

Medium avatar

(310)

on March 02, 2011
at 09:46 PM

Really? WOW! Who would have thought? Thanks!

194d8e8140425057fe06202e1e5822a7

(3979)

on August 08, 2012
at 01:38 AM

Rhodiola Rosea is another herb that is pretty good, in a similar way.

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