How do you cycle off supplements - whether it be magnesium, fish oil etc?

Answered on August 19, 2014
Created January 20, 2012 at 12:24 AM

I was curious how people cycle off supplements.

Do you stop all supplements for 5-7 days every 4-6 weeks? If you do, do you do it when you travel (so you don't have to pack them) or at home when your nutrition is likely far better?

The reason I ask if Robb Wolf in some podcast mentioned he would use melatonin 1 week, and then 1 week off (don't know if he still does that) so it got me to thinking how people cycle off supplements so their body will not lose it's ability to obtain much of the nutrition for food.

Do you cycle off one supplement at a time so maybe fish oil one week and magnesium another?

Should pregnant, nursing, or those trying to conceive cycle off any supplements, such as Prenatal vitamins, fish oil etc. at any time?

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4 Answers



on January 20, 2012
at 12:20 PM

To prevent down-regulation of endogenous biosynthetic pathways, perhaps that's why RW cycles melatonin. Melatonin isn't fit with other vitamin/mineral/nutritonal supplements, as it's also a hormone.

Most supplements are dose in many multiples of the RDA. Taking a day or two off of supplements each week might give your body time to eliminate excess and prevent toxicity of fat-soluble compounds, which are less readily excreted.


on January 20, 2012
at 12:30 AM

Supplements like fish oil, vitamins do not require a cycle.

Some people cycle stimulants.

Others, they cycle anabolic steroids.

I cycle Vitamin D, because taking the same dose everyday bores me and I like to swallow 10-20 little red pills in front of people sometimes. With nothing but positive results, btw. (From the Vit D not necessarily the people)



on January 20, 2012
at 03:53 AM

I personally just take different vitamins/minerals daily, I have put together a plan for me: http://eugenia.queru.com/2012/01/08/a-diet-plan-for-a-healthier-fridge/#plan The only vitamin that I take more often than others is D3.


on January 20, 2012
at 02:06 AM

I don't think supplement use will cause you to be unable to absorb nutrients from food. That sounds ridiculous. Supplemental vitamins are constantly said to be harder for the body to absorb than vitamins from food. Your body would prefer nutrition from food than synthetic pills.

The only reason I've come across for cycling vitamins (when it's not to avoid taking too much) is if there are ingredients in the pills that could be allergenic - in that case you might rotate the supplements as you would foods.

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