Help! Hypothyroid + VLC/LC + Synthroid - Synthroid + Armour - Armour + Cytomel = Serious Weight Gain

Answered on February 13, 2015
Created February 03, 2015 at 2:23 AM

Looking for some serious hacking...After 20 years of various diets/new eating plans (you name them, I've tried them) and zero success in weight loss or weight management plus various failed attempts of severe exercise programs (Body for Life, P90X, Insanity, Bikram Yoga 4x/week), I now turn to a new community in search of answers.

I have been to 3 nutritionists, 2 Endos and 1 DO. The two Endos said: See a nutritionist. Decrease your calories and you will lose weight. The nutritionists said: Decrease your calories and you will lose weight. The DO said: Reduce your carbs and you will lose weight. Yet, none of these approaches have worked for me. I have read the Leptin Reset, The Hormone Diet and Jack Kruse's site and have tried tweaking my diet, including various supplements, VLC, LC, high carb to no weight loss success.

I was on Synthroid for years in increasing doses with increasing weight gain until my Dr. told me being on Synthroid was basically my body "on speed" and virtually forced me to Armour. I willingly went, hoping he would have an answer. I gained 27 pounds in 6 months. During that time, I was Paleo and doing VLC and trying to get into ketosis to lose weight. It never happened. I never lost a pound. They then took me off Armour and put me on time release Cytomel. My energy is so-so. I am literally exhausted by 8pm. My hands and feet are freezing all day; only warming up around 7pm at night. My hair is dry and brittle; same with my nails. My skin is starting to look like it's falling off my face. All signs of low thyroid, even tho I'm "properly medicated" according to my dr.

I am still doing LC but I feel worse than I have in years. Plus the crazy weight gain is enough to make you want to jump in front of a train. (Not depressed, just frustrated.) Somewhere, I missed the research previously that said "hypothyroid individuals should stay away from ketosis" and "hypothyroid individuals should not go VLC or LC". What I'm seeing now is if you have thyroid issues, you need to be around 100g of carbs day. And roughly 1 g protein for your weight divided by 2. Is this accurate? Any suggestions? I am on a host of supplements and really don't feel like anything is doing much for me except making me feel worse.  Recent tests below followed by current supplements.

Most I've ever weighed and I feel worse than I ever have.

5'5 - 41yo F

162 lbs

Recent Labs

TSH - 1.11 (0.4 - 4.5)

FT4 - 1.0 (0.8 - 1.8)

FT3 - 2.7 (2.3-4.2)

RT3 - 19 ( 8-25)

Vit D 25OH Total - 65 (30-100)

A1C - 5.6

HS CRP -0.5

Cholesterol Total - 249 (125-200)

HDL - 77

LDL - 157

Leptin - 12.6 ( Up from 3 months ago - 11.4)

Glucose - 94 (65-99)


Current Supplements






Vitamin D




Past Supplements

I've had my cortisol tested; been on DHEA and pregnenalone for a period then told my levels were up so I could stop.


Time-release Cytomel


Anyone have similar experience? Suggestions on tweaking my nutrition? Supplements?  Thanks in advance!

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1 Answers


on February 13, 2015
at 09:51 PM

Reserach Ray Peat.


Supplementing 5htp is silly. Most profound supplements were anti-serotonin substabces in my case. 


100g f carbs seems ridiculously small for a hypothyroid person. Your cholesterol indicates you are low thyroid, so you likely have to up the dosage. Googlle broda barne's temperature measurement for diagnosis of thryoid disorders.

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