4

votes

Evening Vitamin D3 supplementation

Answered on August 19, 2014
Created February 13, 2012 at 10:10 AM

Any supporting data out there for taking daily D3 supplementation in the evening, rather than mornings?

Irrespective of the fact that D3 is stored in the liver, it seems logical that D3 would normally peak in the bloodstream in the evening after Sun exposure, a few hours after skin synthesis, and eventual release.

My n=1 is that I sleep better, longer, and wake with better mood since switching to evening dosage. (I take 10,000 iu daily from Oct - May, and live in Northern Europe)

Looking for evidence of hormonal synergies, I suppose.

D07a525f9021f8d72bf6aaa52893c795

(1011)

on August 21, 2012
at 11:52 AM

Don't forget to post results! For me it's "Summer recess" - I'm getting lots of Sun exposure - my favourite way to boost levels!

D07a525f9021f8d72bf6aaa52893c795

(1011)

on August 21, 2012
at 11:50 AM

I'm sorry, but I fail to see how your answer is relevant in any way

2f6ef8ed84e943285c1386254d3c66ea

(195)

on August 20, 2012
at 01:17 PM

I've just reading what other people have written below, and I agree with what your saying it defiantly does seem that it would be more logical to supplement with d3 late afternoon/early evening. I'm defiantly going to try this because it makes sense.

34cf7065a6c94062c711eb16c0f6adc3

on February 17, 2012
at 09:53 AM

I would think it makes more sense to get it in the morning than in the evening. Remember the hunter/gatherers would be already having enough vitD. The sunlight will merely provide a way to set the circadian rhythm. Anyway you should try it out, don't discard the notion, just because you think that it will be better in the evening. Everybody is different and unless you try it, you wouldn't know. And if you can't make out any difference, then how does it matter when you take it

34cf7065a6c94062c711eb16c0f6adc3

on February 17, 2012
at 09:52 AM

I would think it makes more sense to get it in the morning than in the evening. Remember they would be already having enough vitD. The sunlight will merely provide a way to set the circadian rhythm. Anyway you should try it out, don't discard the notion, just because you think that it will be better in the evening. Everybody is different and unless you try it, you wouldn't know. And if you can't make out any difference, then how does it matter when you take it.

D07a525f9021f8d72bf6aaa52893c795

(1011)

on February 16, 2012
at 07:40 PM

Let's be clear about timing. Even in equatorial Africa, there will still be a required elevation before UV of the required wavelength will "shine through" - so the "D3 day" will be of similar length to midsummer in UK. Secondly, perfusion of synthesised D3 from the skin into the bloodstream is far from instantaneous - SEVERAL HOURS after exposure. Weighing it all up, my logic says that oral D3 in the evening is the most harmonious with ancestral biochemistry. That said, I'm still hoping for some modern biochemical evidence in support of this idea. Thanks for indulging me this far!

34cf7065a6c94062c711eb16c0f6adc3

on February 15, 2012
at 05:53 AM

I missed adding that humans evolved in Africa. So yes our body prefers it in the morning. If you don't get in the morning yes it will get it in the evening, but that is not what our body likes. Since you are taking it artificially it would be better to go with what the body expects, ie in the morning. Anyway your own experiment matters to you. Everybody should do their tests on themselves to know. Some will find benefits in the morning others won't.

D07a525f9021f8d72bf6aaa52893c795

(1011)

on February 13, 2012
at 02:22 PM

I have to reject the hypothesis, since no D3 would be synthesised in the early morning. The UV wavelength required is essentially absent before 10am (and after 2pm) in Northern latitudes. My n=1 is sufficient for me to question other testimonials. Of course, it may be that D3 levels are raised by release from storage in the morning - not seen any lit on diurnal levels..

  • D07a525f9021f8d72bf6aaa52893c795

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5 Answers

5
34b560c8b9ce660d7839fb7e29d7be89

on February 13, 2012
at 10:34 AM

My under standing is that the two trains of thought are this: one, that correcting D levels in general leads to improved sleep, and two, that D may be linked to circadium rythyms because of it's link with sunlight and thus can disrupt sleep when taken late in the day. The results seem mixed, based on anecdotal evidence, so if you are not experiencing any negative effects than I see no reason not to stick to the findings of your N=1 results.

3
66974b2cb291799dcd661b7dec99a9e2

(11121)

on February 13, 2012
at 02:32 PM

In my N=1 I take Vit D in the morning, so does the rest of my family. I have found, through years of experimentation that if I need an 'energy boost' (say for a late night) I just take about 10,000IU Vit D, some Chromium (500mcg) and a couple table spoons of Coconut oil - I get a nice, gradual energy boost for a few hours (much better than red bull), I don't crash and no unwanted side effects.

2
34cf7065a6c94062c711eb16c0f6adc3

on February 13, 2012
at 12:31 PM

I think that our body is designed to get most of it in the early morning, at least wherever the sun is very bright. The hunter/gatherer would get up with the sun, and would be nearly naked, and would be working in the sun, so the vitamin D production will peak very early in the morning and then the body will stop producing it, because the limit is reached. This means that it is best to take Vitamin D very early in the morning, basically within a couple of hours of getting up.

Seth Roberts has written several articles on the benefits of taking VitD early in the morning. This is just the top of the search. check out. http://blog.sethroberts.net/2011/11/28/vitamin-d-more-reason-to-take-at-sunrise/

D07a525f9021f8d72bf6aaa52893c795

(1011)

on February 13, 2012
at 02:22 PM

I have to reject the hypothesis, since no D3 would be synthesised in the early morning. The UV wavelength required is essentially absent before 10am (and after 2pm) in Northern latitudes. My n=1 is sufficient for me to question other testimonials. Of course, it may be that D3 levels are raised by release from storage in the morning - not seen any lit on diurnal levels..

D07a525f9021f8d72bf6aaa52893c795

(1011)

on February 16, 2012
at 07:40 PM

Let's be clear about timing. Even in equatorial Africa, there will still be a required elevation before UV of the required wavelength will "shine through" - so the "D3 day" will be of similar length to midsummer in UK. Secondly, perfusion of synthesised D3 from the skin into the bloodstream is far from instantaneous - SEVERAL HOURS after exposure. Weighing it all up, my logic says that oral D3 in the evening is the most harmonious with ancestral biochemistry. That said, I'm still hoping for some modern biochemical evidence in support of this idea. Thanks for indulging me this far!

34cf7065a6c94062c711eb16c0f6adc3

on February 15, 2012
at 05:53 AM

I missed adding that humans evolved in Africa. So yes our body prefers it in the morning. If you don't get in the morning yes it will get it in the evening, but that is not what our body likes. Since you are taking it artificially it would be better to go with what the body expects, ie in the morning. Anyway your own experiment matters to you. Everybody should do their tests on themselves to know. Some will find benefits in the morning others won't.

34cf7065a6c94062c711eb16c0f6adc3

on February 17, 2012
at 09:53 AM

I would think it makes more sense to get it in the morning than in the evening. Remember the hunter/gatherers would be already having enough vitD. The sunlight will merely provide a way to set the circadian rhythm. Anyway you should try it out, don't discard the notion, just because you think that it will be better in the evening. Everybody is different and unless you try it, you wouldn't know. And if you can't make out any difference, then how does it matter when you take it

34cf7065a6c94062c711eb16c0f6adc3

on February 17, 2012
at 09:52 AM

I would think it makes more sense to get it in the morning than in the evening. Remember they would be already having enough vitD. The sunlight will merely provide a way to set the circadian rhythm. Anyway you should try it out, don't discard the notion, just because you think that it will be better in the evening. Everybody is different and unless you try it, you wouldn't know. And if you can't make out any difference, then how does it matter when you take it.

1
Ca2c940a1947e6200883908592956680

(8574)

on February 13, 2012
at 01:25 PM

If I am invited out in the evening I take another two pills (5000ui) and though I cannot say for sure, I find it gives me a little lift throughout the evening. In my mind supplementation should be in the morning to coincide with sunlight. Thus when I need that extra pick-up I take again early evening in attempt to extend my 'daylight'.

-2
6737e3b0e9e2f7abdfb1a180e97d8e23

on August 21, 2012
at 11:24 AM

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You can read this story for more info : Red Bull Side Effects | Side Effects Guide

D07a525f9021f8d72bf6aaa52893c795

(1011)

on August 21, 2012
at 11:50 AM

I'm sorry, but I fail to see how your answer is relevant in any way

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