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Taper off Seroquel 25mg XR

Answered on August 19, 2014
Created December 27, 2012 at 7:24 PM

I'm on Seroquel 25mg XR from 6 months ago for Sleep aid, and it works fine, What is the best way to stop such dose ? in my country the smallest dose is 50mg for XR and I take half every day, so take it day-on day-off ? or reduce to 12 mg?

Please I need professional advice, with details (schedule ...)

Many thanks

Ab136abf1904c5f7908f3df596bf18c3

(80)

on January 03, 2013
at 06:35 PM

Seems like you walked in wanting to come off drugs and came out having upped the dose and committed to staying on it for at least a 50% longer amount of time? Not sure what happened there but good luck with it, hope it all works out.

0c39847e2e43df551e2a5ecba330ae35

on January 03, 2013
at 11:06 AM

Many thanks @MiMintzer this is the most useful info about XR, actually it was my fault, because I thought that half was working fine, I have checked with my prescriber he gave me the same comment, DONT NOT SPLIT THAT XR DOES, I did that on my own, now, I'm on 50 mg XR instead of taper off, and will discuss the discontinuation later after 3 months as my doctor suggest., many thanks for your useful help and thank again MiMintzer.

Ab136abf1904c5f7908f3df596bf18c3

(80)

on January 03, 2013
at 02:23 AM

I'd just add to this that if you are going to add supplements etc (I'm talking in general not these ones specifically) add them before you taper not while you taper, and take them for a couple of weeks before you start tapering. If anything goes wrong or weird knowing what did it (whether it's the supplement or withdrawal) will be very useful. Also if you add before starting to taper you'll be adding to a stable system rather than one that's in a state of flux, which is much to your benefit.

Ab136abf1904c5f7908f3df596bf18c3

(80)

on January 03, 2013
at 01:40 AM

Really good point here, the XR tabs are not meant to be split but the plain ones can. Move to equivalent dose of standard version and don't start taper for a couple of weeks to check moving from XR hasn't caused any effects.

782d92f4127823bdfb2ddfcbcf961d0e

(5231)

on December 31, 2012
at 05:18 AM

Matt: If it is being used as a sleep aid I don't think that it is unreasonable to want to get off it. Not necessarily related to paleo magic diet.

F0a9dea438e7943fa05da318773e785e

on December 31, 2012
at 01:44 AM

If you aren't going to follow your doctor's recommendations, then you need to talk to him or her about your reasoning. They can make suggestions on something better for your needs/issues. But please do follow their advice if you plan to stop taking such a powerful medication. Risperdal is a psychotropic medication and can have serious side effects if not taken as recommended.

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2012
at 02:47 AM

Is paleo some magic diet that lets you stop taking all drugs? **NO.**

3327924660b1e2f8f8fc4ca27fedf2b2

(2919)

on December 27, 2012
at 07:42 PM

Tell your doctor that you don't want to take drugs anymore.

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4 Answers

best answer

1
782d92f4127823bdfb2ddfcbcf961d0e

on December 31, 2012
at 05:15 AM

Are you splitting the XR tab? I don't think that they are meant to be split as XR stands for extended release and breaking the tablet will change the way the med becomes active once ingested. Have your prescriber write you a script for the plain tablets which can be split (you'll need a pill splitter since they are not scored). You will have to taper the dose down but since you are on a low dose I don't think it will take too long to do, maybe a week or two. Ask your prescriber for a dosing schedule to wean off it.

Ab136abf1904c5f7908f3df596bf18c3

(80)

on January 03, 2013
at 06:35 PM

Seems like you walked in wanting to come off drugs and came out having upped the dose and committed to staying on it for at least a 50% longer amount of time? Not sure what happened there but good luck with it, hope it all works out.

0c39847e2e43df551e2a5ecba330ae35

on January 03, 2013
at 11:06 AM

Many thanks @MiMintzer this is the most useful info about XR, actually it was my fault, because I thought that half was working fine, I have checked with my prescriber he gave me the same comment, DONT NOT SPLIT THAT XR DOES, I did that on my own, now, I'm on 50 mg XR instead of taper off, and will discuss the discontinuation later after 3 months as my doctor suggest., many thanks for your useful help and thank again MiMintzer.

Ab136abf1904c5f7908f3df596bf18c3

(80)

on January 03, 2013
at 01:40 AM

Really good point here, the XR tabs are not meant to be split but the plain ones can. Move to equivalent dose of standard version and don't start taper for a couple of weeks to check moving from XR hasn't caused any effects.

1
Ab136abf1904c5f7908f3df596bf18c3

on January 03, 2013
at 02:09 AM

General advice here is:

As with all psychiatric drugs don't just stop, taper down, if you run into any problems at the new dose if they are not too debilitating hold for at least a couple of weeks or until you have stabilized (whichever is longest!). If they are unmanageable or severe quickly return to the previous dose and hold there for a while and then taper at a lower rate in the future.

Try to taper at the smallest amounts you can, especially as you approach zero. Standard advice is to taper down by 10% of the dose at a time. The second taper should be of 10% of the new amount you are tapering from not 10% of the original dose. Time between tapers should not be less than two weeks.

Do not listen to anyone who says antipsychotics don't have withdrawal problems. Sure not everyone has them and some people have few or no problems but they can be severe, which is why erring on the side of caution is advisable. As you've been on a small dose for a short time the odds are that you will be much better off than many others and that 10% at a time may not be practical/necessary - but still taper as small as feasibly possible and hold if you have problems.

Try to find a supportive Doctor to help you through this time. If your Doctor is supportive great, if not find another one. Consider getting peer support online or in person. If anyone ever says there are no problems possible withdrawing from these drugs please kick em in their tender parts.

If you have supportive and loving people that you trust in your life tell them what you are doing so they can support you.

I'd suggest having a look at this:

http://theicarusproject.net/HarmReductionGuideComingOffPsychDrugs

Do not do the day on day off thing. Tapering safely is about reducing the amounts not frequencies. Increasing the spacing as opposed to reducing the dosage is a bad thing to do.

Just in case anyone needs a warning - don't even think of messing about with other drugs whilst doing this, your body and brain need stability whilst adjusting to the removal of these substances.

Try to pick times which aren't particularly stressful for reducing doses, it makes it easier to distinguish withdrawal effects from stress reactions to events in your life.

If you happen to smoke consider stopping first if it's possible - it makes seroquel leave your body quicker which is a bad thing, longer half-life makes it easier to withdraw from (I know this contradicts slightly the switch from XR advice but that's mainly because you can't cut XR).

Good luck to you and anyone else doing this.

0
F0a9dea438e7943fa05da318773e785e

on December 31, 2012
at 01:42 AM

First, I'm not a doc, I'm a mental health grad student who has taken pharmacology, so take my advice for what you will. I'm not a doc yet or anything.

Second, psychotropic meds are some of the hardest to wean off of, period.

Third, I would not do so without a physicians advice, because your physician knows your health history and knows any other issues you may be facing.

Lastly, you can very easily google dosing schedules, but they will not necessarily be accurate based on your needs. I personally take l-theanine (100mg) and melatonin (15mg) for sleep, so perhaps a combination will work for you if you begin it while you are tapering off of the Seroquel XR (which the dose you are taking of is relatively low, BTW).

Good luck and please seek medical advice. Even if you just call your physician and let him/her know your intent, it can't hurt.

Ab136abf1904c5f7908f3df596bf18c3

(80)

on January 03, 2013
at 02:23 AM

I'd just add to this that if you are going to add supplements etc (I'm talking in general not these ones specifically) add them before you taper not while you taper, and take them for a couple of weeks before you start tapering. If anything goes wrong or weird knowing what did it (whether it's the supplement or withdrawal) will be very useful. Also if you add before starting to taper you'll be adding to a stable system rather than one that's in a state of flux, which is much to your benefit.

0
Bbae431256192d2c57ba2a2122d12cd3

(84)

on December 27, 2012
at 08:47 PM

I have the same question too, I want to quit risperdal 1mg.

Until recently I was told by my pdoc to take 2mg everyday.

I hope my pdoc will help me to quit the risperdal

F0a9dea438e7943fa05da318773e785e

on December 31, 2012
at 01:44 AM

If you aren't going to follow your doctor's recommendations, then you need to talk to him or her about your reasoning. They can make suggestions on something better for your needs/issues. But please do follow their advice if you plan to stop taking such a powerful medication. Risperdal is a psychotropic medication and can have serious side effects if not taken as recommended.

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