1

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Replacing Sat Fat with PUFA reduces CHD?

Answered on August 19, 2014
Created June 14, 2011 at 11:38 PM

This seems to go against everything I've been reading in the last year. Anyone have an opinion as to what's going on in this study? It looks like the "risk" factor was the ratio of total cholesterol : HDL, and replacing SFA with PUFA resulted in a better ratio.

EDIT: Oops - http://www.ncbi.nlm.nih.gov/pubmed?term=20351774

3a833804187fe8926214e6c0bd8a0766

(1023)

on June 15, 2011
at 01:03 AM

Great, thanks. Every time I see a study like this, it seems I search a little and find someone already debunked it

3a833804187fe8926214e6c0bd8a0766

(1023)

on June 14, 2011
at 11:52 PM

Sorry! http://www.ncbi.nlm.nih.gov/pubmed?term=20351774

Af1d286f0fd5c3949f59b4edf4d892f5

(18452)

on June 14, 2011
at 11:47 PM

you forgot to post the link Jimbo :)

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2 Answers

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1
0242b468fe1c97997749db416c92e7ed

(4528)

on June 15, 2011
at 12:44 AM

This meta-analysis bothered me too when it was first released. I asked the Paleohackers for perspective, and received some great responses.

Stephan Guyenet also weighed in on his blog.

To quote HealthRediscovery, "This paper is a breathtaking example of how far a person will go to confirm his own pre-existing ideas."

3a833804187fe8926214e6c0bd8a0766

(1023)

on June 15, 2011
at 01:03 AM

Great, thanks. Every time I see a study like this, it seems I search a little and find someone already debunked it

1
B3e7d1ab5aeb329fe24cca1de1a0b09c

(5242)

on June 14, 2011
at 11:49 PM

Maybe a link to said study?

Without looking at the study, SFA can affect total cholesterol levels. So replacing SFA with PUFA in a short term study, may give you a better 'number', but did people actually develop less CHD?

Chris Master-John made an observation on Chris Kessler's podcast that it appears to take around 8 years for cholesterol studies to start producing useful results.

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