Saturated fats are good for you. Studies done with the standard American diet have failed to find a correlation between saturated fat intake and heart disease, mortality, or most other ailments.

For more info, see http://rawfoodsos.com/2011/02/04/the-new-usda-dietary-guideline/

Also, if you eat a lot of PUFA, your body stores the fat as PUFA, which is more susceptible to oxidizing, and thus can be inflammatory. Thus, (in my opinion), saturated fat is better for you than PUFA, and should be eaten liberally, regardless of ones carbohydrate intake.

In addition, the scientific studies have not looked at grass fed animals and saturated fat content, so the scientific studies are using the "worst" type of saturated fats, and still come to the conclusion that they are not bad for you.

Richard Feinman says that the ???deleterious effects of fat have been measured in the presence of high carbohydrate. A high fat diet in the presence of high carbohydrate is different than a high fat diet in the presence of low carbohydrate.???

It's possible that Paleo carbs possess magic powers that prevent this evil synergy, but it's not something I'd hang my hat on.

"Relatively high-starch" is so ambiguous it's nearly impossible to answer the question. Relatively high-starch compared to what? Ketogenic? SAD? Sedentary vs extremely active? As a general rule, anyone following a Paleo diet is going to be on the lower-end of the curve when it comes to starch intake. Someone who is using starch as a fuel source for activity or sport is going to be even lower. Finally, someone who is only eating the right type of starch and limiting other forms of carbohydrate it going to be even better. It's a sliding scale that's very difficult to answer outside of an N=1.

Atherosclerosis has a lot of possible causes, but the one I see which could be related to the sat fat/high carb scenario is diabetes. I'd suggest getting a blood glucose monitor and checking your blood glucose levels. If they are high and don't come down a few hours after a meal, talk to your doctor. It's not related to the amount of carbs you eat so much as whether you're insulin resistant and can't clear the glucose out of your bloodstream.

I would like to know about this as well. Back when I was doing an atkins type low carb, everyone seemed to warn against carb creep as they said combining high fat and high carb was a dangerous combo. Now that I'm paleo I eat a healthy amount of carbs (potatoes, rice, starchy veggies) without thinking twice. Should I be concerned about combining such high levels of fat with moderate levels of carbs (75-150g daily).