1

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Do saturated fats worsen insulin resistance? Study attached.

Answered on August 19, 2014
Created February 24, 2011 at 5:52 PM

http://www.ncbi.nlm.nih.gov/pubmed/15297079

I'm still new to the paleo lifestyle so when I see a study like that, it worries me a little, even though I know it's probably hogwash. What do you guys think of the conclusion they drew? That saturated fat worsening insulin resistance?

It also suggests replacing unsaturated fats with sat. fats improves plasma triglyceride levels?

77877f762c40637911396daa19b53094

(78467)

on March 08, 2012
at 08:41 AM

50% fat, 15% protein (standard in most populations) means that they were only getting 25ish from carb. Low carb+high fat=no problem. High fat+ High Carb = Big problem.

8a3fdcbbec724506de15c14bb6271264

(435)

on March 03, 2011
at 05:06 AM

Another great link! I'm no longer worried about sat. fats.

8a3fdcbbec724506de15c14bb6271264

(435)

on March 03, 2011
at 05:05 AM

Yes, thank you!

Medium avatar

(39821)

on February 24, 2011
at 07:01 PM

Thanks for the great links.

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5 Answers

best answer

2
Aa3a90ba6f6a6d488f28cfcdc4e05627

on February 24, 2011
at 06:46 PM

Medium avatar

(39821)

on February 24, 2011
at 07:01 PM

Thanks for the great links.

8a3fdcbbec724506de15c14bb6271264

(435)

on March 03, 2011
at 05:05 AM

Yes, thank you!

0
C82165f187e0c2c6413e91aeb050ea53

on September 06, 2011
at 09:37 AM

Copied from another web site: Insulin cannot do its job of driving sugar from the bloodstream into cells until it attaches on hooks on a cell's surface called insulin receptors. Eating too much fat and being fat decrease the number of insulin receptors and cause diabetes. Excess insulin production by the pancreas can also cause diabetes. Eating refined carbohydrates in sugar-added foods and drinks, bakery products and pastas calls out the most insulin and therefore increases risk for diabetes.

"as dietary fat has zero insulin response."

But as stated above, on Gabe Mirkin, M.D.'s web site, dietary fat decreases the number of insulin receptors!!!

0
9c6d062149e141dab12de1461dce84cc

on April 28, 2011
at 11:25 AM

The first link is not a study at all. The second is an opinion piece that links to one study which shows no increase in insulin resistance on even a high fat high GI diet which is not at all paleo.

So at the moment this question/thread contains zero evidence to suggest that saturated fats worsen insulin resistance.

Which makes sense, as there is a large body of evidence to show that they do the opposite. Which also makes sense, as dietary fat has zero insulin response.

0
461281c9092d3cb306b46831064e2fc4

on February 24, 2011
at 06:34 PM

This is just a review article. To accurately evaluate their conclusions, you need to read the original sources and also find out which studies were excluded from the review and why. Review articles (especially those that don't employ meta-analysis) can be horribly biased.

0
4145b36f1488224964edac6258b75aff

(7821)

on February 24, 2011
at 06:27 PM

Makes me wonder how it is the Tokelau islanders weren't insulin-resistant wrecks, given that they took 50% of their daily calories as saturated fat.

When I read studies like this, I usually think, "I wonder how they controlled for all the stuff they don't know yet." The answer is of course that they didn't, and likely didn't even properly control for what they did know. I wonder what the study's authors would say to the Tokelau data.

8a3fdcbbec724506de15c14bb6271264

(435)

on March 03, 2011
at 05:06 AM

Another great link! I'm no longer worried about sat. fats.

77877f762c40637911396daa19b53094

(78467)

on March 08, 2012
at 08:41 AM

50% fat, 15% protein (standard in most populations) means that they were only getting 25ish from carb. Low carb+high fat=no problem. High fat+ High Carb = Big problem.

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