0

votes

Will you continue eating rice after this piece of news?

Answered on August 19, 2014
Created September 22, 2011 at 11:32 AM

Loaded question I know, but this is a really interesting piece on DNA being changed by the foods we eat.

We Incorporate Genetic Information From the Food We Eat, New Study Finds

77877f762c40637911396daa19b53094

(78467)

on October 24, 2011
at 10:56 AM

A great article about this study, here: http://evolvify.com/rice-wheat-potatoes-interfere-with-gene-expression/

77877f762c40637911396daa19b53094

(78467)

on September 23, 2011
at 07:00 AM

Or it might not be a problem. Maybe that is the unity of life, and is supposed to work that way.

77877f762c40637911396daa19b53094

(78467)

on September 23, 2011
at 06:59 AM

Yes, but ... just as you eat DNA from dead cells you eat miRNA. Its not a problem. The problem is if those miRNAs enter the cell and have active role. The same thing could happen to protein - its typically digested but may escape via leaky gut and have active role. SO, I am not concerned at all about this for now.

742ff8ba4ff55e84593ede14ac1c3cab

(3536)

on September 22, 2011
at 11:28 PM

HAHAHAH... the comments on popsci regarding the article are great.

667f6c030b0245d71d8ef50c72b097dc

(15976)

on September 22, 2011
at 04:17 PM

I think I'm going to start eating rice from this thread.

0bc6cbb653cdc5e82400f6da920f11eb

(19235)

on September 22, 2011
at 03:17 PM

@majkinetor - Interesting, raw milked contained 245 miRNA's. I wonder what effects they might have.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:48 PM

Hey, its everywhere : "It is worth noting that these three plant miRNAs, MIR168a, MIR156a, and MIR166a, were detected in other foods, including Chinese cabbage (Brassica rapa pekinensis), wheat (Triticum aestivum), and potato (Solanum tuberosum). Interestingly, plant miRNAs were stable in cooked foods."

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:38 PM

I don't see why such thing wouldn't happen with animal food tbh. Actually, it looks like the same group (hm, lots of similar sounding chinese names) provided evidence that cow's milk contain large amounts of miRNA. http://www.nature.com/cr/journal/v20/n10/full/cr201080a.html

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:35 PM

I don't see why such thing wouldn't happen with animal food tbh.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:35 PM

Anyway, if true that miRNA can survive digestion and get imported into nucleous, then that doesn't mean it has negative effect guarantied, but GMO changed miRNAs might since they are not selected by evolution. You could be proactive and limit extensive usage of any food.

Fa9f340eddbad9a544184c688fa4dcdd

(6433)

on September 22, 2011
at 12:29 PM

Welcome to the fascinating world of epigenetics.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:27 PM

Its more probable that GMO food bad effects are due to the effects on environment and also the fact that protein isn't digested to single amino-acids but polypeptides which also have biological role (thats why protein shakes are not equal to live protein). Now, I am not sure if small RNAs can escape digestion, couldn't find anything about it so far. miRNAs are typically around 20 bases long. I think leaky gut due to the plant lectins is probably to blame for intrusion...

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:24 PM

Dietary nucleic acids are digested by pancreatic enzymes. Since they are large molecules I doubt they can cross the epithelium per se. Now, if you have leaky gut you could probably get some of it 'imported' which then have to enter cell, then enter nucleus and survive degradation inside the cell. So, I think not, terrifying new era of rice-human hybrids is probably out of question. I will research this further as lots of anti-GMO claims don't make much sense.

Ed71ab1c75c6a9bd217a599db0a3e117

(25477)

on September 22, 2011
at 12:23 PM

This is how foods change epigenetics switches......its heavily influenced by methylaion and acetylation.

De65560c40ddb3f27764307ffa504240

on September 22, 2011
at 12:10 PM

Does this mean that we're *not* ushering in a terrifying new era of rice-human hybrids?

9d43f6873107e17ca4d1a5055aa7a2ad

on September 22, 2011
at 12:06 PM

free fulltext http://www.nature.com/cr/journal/vaop/ncurrent/full/cr2011158a.html

9d43f6873107e17ca4d1a5055aa7a2ad

on September 22, 2011
at 12:05 PM

here is a better article http://blogs.discovermagazine.com/80beats/2011/09/21/what-you-eat-affects-your-genes-rna-from-rice-can-survive-digestion-and-alter-gene-expression/

9d43f6873107e17ca4d1a5055aa7a2ad

on September 22, 2011
at 12:01 PM

Um, other foods probably do this too

B0454de6d4f4cdd9ca2e59021dc105bf

(606)

on September 22, 2011
at 11:43 AM

Link goes to Popsci.com if anyone's nervous about clicking it!

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3 Answers

11
77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 11:59 AM

DNA is not being changed, you read it wrong and the title is stupid. Its about miRNAs, very short nucleotide sequences that suppress specific gene. So you may get your DNA expression changed for some short time since miRNAs are degraded by the cell.

The fact that "MicroRNA is also used in the genetic engineering of crops, as a method of RNA interference." has nothing to do with this. To be constantly prohibiting, miRNA gene has to be inserted into the organism's genome which is done via virus or bacterial plasmid.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:48 PM

Hey, its everywhere : "It is worth noting that these three plant miRNAs, MIR168a, MIR156a, and MIR166a, were detected in other foods, including Chinese cabbage (Brassica rapa pekinensis), wheat (Triticum aestivum), and potato (Solanum tuberosum). Interestingly, plant miRNAs were stable in cooked foods."

0bc6cbb653cdc5e82400f6da920f11eb

(19235)

on September 22, 2011
at 03:17 PM

@majkinetor - Interesting, raw milked contained 245 miRNA's. I wonder what effects they might have.

77877f762c40637911396daa19b53094

(78467)

on September 23, 2011
at 06:59 AM

Yes, but ... just as you eat DNA from dead cells you eat miRNA. Its not a problem. The problem is if those miRNAs enter the cell and have active role. The same thing could happen to protein - its typically digested but may escape via leaky gut and have active role. SO, I am not concerned at all about this for now.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:27 PM

Its more probable that GMO food bad effects are due to the effects on environment and also the fact that protein isn't digested to single amino-acids but polypeptides which also have biological role (thats why protein shakes are not equal to live protein). Now, I am not sure if small RNAs can escape digestion, couldn't find anything about it so far. miRNAs are typically around 20 bases long. I think leaky gut due to the plant lectins is probably to blame for intrusion...

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:24 PM

Dietary nucleic acids are digested by pancreatic enzymes. Since they are large molecules I doubt they can cross the epithelium per se. Now, if you have leaky gut you could probably get some of it 'imported' which then have to enter cell, then enter nucleus and survive degradation inside the cell. So, I think not, terrifying new era of rice-human hybrids is probably out of question. I will research this further as lots of anti-GMO claims don't make much sense.

Ed71ab1c75c6a9bd217a599db0a3e117

(25477)

on September 22, 2011
at 12:23 PM

This is how foods change epigenetics switches......its heavily influenced by methylaion and acetylation.

De65560c40ddb3f27764307ffa504240

on September 22, 2011
at 12:10 PM

Does this mean that we're *not* ushering in a terrifying new era of rice-human hybrids?

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:38 PM

I don't see why such thing wouldn't happen with animal food tbh. Actually, it looks like the same group (hm, lots of similar sounding chinese names) provided evidence that cow's milk contain large amounts of miRNA. http://www.nature.com/cr/journal/v20/n10/full/cr201080a.html

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:35 PM

Anyway, if true that miRNA can survive digestion and get imported into nucleous, then that doesn't mean it has negative effect guarantied, but GMO changed miRNAs might since they are not selected by evolution. You could be proactive and limit extensive usage of any food.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 12:35 PM

I don't see why such thing wouldn't happen with animal food tbh.

77877f762c40637911396daa19b53094

(78467)

on September 23, 2011
at 07:00 AM

Or it might not be a problem. Maybe that is the unity of life, and is supposed to work that way.

77877f762c40637911396daa19b53094

(78467)

on October 24, 2011
at 10:56 AM

A great article about this study, here: http://evolvify.com/rice-wheat-potatoes-interfere-with-gene-expression/

2
1d0497f8781845ab371b479455bfee8e

(11157)

on September 22, 2011
at 11:43 AM

But the Chinese eat rice with virtually every meal. I eat it >1x per every other week, and even then only a serving's worth. Not enough to make a difference ;)

0
26b7615ef542394102785a67a2786867

on September 22, 2011
at 11:58 AM

I think my DNA is already done changed... I grew up eating lots of 'healthy whole grains' and I ate a crappy grain-based diet until just 2 years ago. And low LDL runs in my family, anyway. Mine is in the 80s. I need starch, so. I'm sure any vegetation leaves it's mark - I'm probably just full of spinach (my favorite).

Epigenetics is fascinating, isn't it?

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