Hydroxyapatite constitutes much of the material your bones are made of. Below are some clinical studies observing the effects of a nano-hydroxyapatite toothpaste's effects on teeth.
- Polishing and whitening properties of toothpaste containing hydroxyapatite.
- Remineralization Potential of New Toothpaste Containing Nano-Hydroxyapatite
It turns out that toothpastes using hydroxyapatite as the active ingredient are being shown to be significantly more effective than fluoride based toothpastes and dentifrices for:
- Preventing caries
- Treating hypersensitivity
- Curing periodontal diseases
- Whitening teeth
- Remineralization of caries (in vitro)
There's also some promising research using hydroxyapatite to attenuate the effects of aging on bone loss and that it is significantly more effective than straight calcium supplements.
- http://www.ncbi.nlm.nih.gov/pubmed/6287835 (11+% increase in bmd in post-menopausal women)
So what is your take on hydroxyapatite/nano-hydroxyapatite? Have you ever heard of it, or tried it either in your toothpaste, as a supplement or perhaps you've had an implant that's utilized hydroxyapatite?
asked byStephen_4 (10989)
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on June 03, 2013
at 08:10 PM
Heard of it, yes. I did a course on Supramolecular chemistry as part of my Masters that covered the crystal structure of bone (which is composed of an inorganic element - hydroxyapatite crystals - and an organic element - collagen fibres. The latter is what gives bones their 'spring' ie. some degree of flexibility)
For sure I can see how hydroxyapatite could help, by "filling in" any gaps in the crystal structure of bone that develop on a molecular level over time. Maybe it could help fill in cracks on a macro-scale, too, but this would be slower In regular bone this might be limited by the loss of the collagen over time, meaning that the framework as well as the crystal molecular structure of the bone is compromised, but the chemical structure of tooth enamel is distinct from regular bone in that a) the hydroxyapatite crystal is very organised and b) It doesn't contain any collagen, and hardly contains any organic components at all which is why it's so brittle. In light of this, I suppose nano-hydroxyapatite would be more effective than regular hydroxyaptite.
I can see how supplementation of hydroxyapaptite would be better than pure calcium - bones are not made of calcium...but, there's an issue, which is this -
Ca10(PO4)6(OH)2(s) + 8H+(aq) ??? 10Ca2+(aq) + 6HPO42-(aq) + 2H2O(l)
What I'm saying is that hydroxyapatie (Ca5(PO4)3(OH), usually written Ca10(PO4)6(OH)2 as the crystal unit cell is made up of two), is soluble in acid, and the stomach is very acidic.
Implants have a hydroxyapatite coating to effectively act as a "seed" crystal