"Fecal bacteriotherapy, also known as fecal transfusion, fecal transplant, or human probiotic infusion (HPI), is a medical treatment for patients with pseudomembranous colitis (caused by Clostridium difficile), or ulcerative colitis which involves restoration of colon homeostasis by reintroducing normal bacterial flora from stool obtained from a healthy donor (Wikipedia).
This topic has been a great interest of mine since it seems that could help so many people so quickly.
This post is only part 1, collecting info on fecal transplant, while part 2 would focus on changing the world - DIY procedure.
NY Times ???That (her husbands microbes) community was able to function and cure her disease in a matter of days???
TheScientist "The results were nothing short of surprising, Borody said. Within days her colitis was gone, never to return."
Ayers (he talks more about it in the comments)
Part I analysis - 4 succesfull, one short (3 months) term and one failed.
Summary version - I did a fecal transplant, after 2 1/2 weeks I have seen amazing results. Worked better than any drug or diet modification
"Did just 2 doses (I was the donor - did it at home) and he noticed something different within 24 hours. Has been symptom free ever since. Feels great and can't believe how he has a normal life back!"
As for the "haters":
"Our colons are not just full of bacteria, but they can also be populated with viruses, fungi, and protozoa"
"One of the 16 survivors experienced a single recurrence of C. difficile colitis during 90???day follow???up. No adverse effects associated with stool treatment were observed."
"We report a case series (n = 7) where 100% clinical success was achieved in treating these individuals with up to 14 months of follow-up."
We can't detect all the possible "bad guys" in the poo
Any thoughts on this ?
asked byIkco (2399)
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on February 02, 2012
at 02:12 AM
First post here so forgive any toe-stepping.
Heard about FT via the SciAm article for C diff but never considered using it for my UC (diagnosed in 1986, steroid dependent). Decided to try it after GI doc tried to force me to have surgery. Just did my second weekly enema last night. No major changes yet but pre-FT I only BM once a day and it was relatively normal. Hopefully FT will allow me to drop all my UC meds and still have normal BMs.
As for the concerns about donor stools harboring some unknown bad bugs, I'm willing to roll the dice. My donor was a 4 year old whose stools are a work of art and has more energy than anyone I know. If said donor has anything nasty hiding in the poo, it will be news to all the docs she sees regularly. I know there are unknown risks in this procedure but if I do nothing, my outcome is guaranteed to be surgery and that is something I want to avoid.
Time is not on my side and I can't wait for a bunch of hand-wringing scientists to do the work for me. Its too easy to get bogged down in possible risks and end up doing nothing. Scientific research usually progresses slowly and there's a good reason for that but I'm the lab rat on the receiving end of the enema bottle so I'm comfortable with said risks.
on February 02, 2012
at 04:55 AM
I suspect it works because it bypass the stomach acid entirely. I'm curious on how it effects the mind too. I assume they place it up in the colon and not small intestine.
on November 12, 2010
at 05:55 PM
Very interesting but we need to see more clinical trials on this to see what the true success rate is. There may be many people who this did not work for who are just not interested in talking about it due to the 'ick' factor. We don't yet know which problems it does and does not work for. And it could be that without lifestyle changes, ie eating healthier, old problems could reoccur. However, I do think that research in this area has the potential to revolutionize common understanding of many problems, how they develop, and how they might be better cured.
on November 12, 2010
at 10:41 AM
We need to know more about this, but most of all, we need to be asking why it works and works so well. So many of us are using incredibly expensive supplements to fix our gut bacteria with very little change. I'm puzzled why this provides such immediate relief in so many cases. What are we missing?
Also, I'm curious how long the improvement lasts. I didn't see much info on this. I'd like to know how expensive the procedure is...and if insurance companies will be covering it.
on September 07, 2013
at 12:44 AM
It doesn't always work. This is a common last resort sort of maneuver for people with UC/Crohn's and while it works for some for others it does nothing, or even, to quote someone in one of those threads, causes a flare:
Hey LuckyLindy-- that is very encouraging, and I am very happy for you! I tried it with my wife's stool as well- I even spent $1500 having her tested first(even though it seeemd silly to since we share germs- but just wanted to rule out anything that might worsen my UC). In my case, I actually flared after trying it ... somehow or another her stool must have been incompatable. Like you I didn't do the antibiotics or fiber part of the regimen. Anyway, early good results for you indicate you may have found the magic bullet and I certainly hope so. Thanks for sharing.
It's not magic but it is certainly an interesting option.
on June 30, 2011
at 07:45 PM
I've been considering it, after having to take a course of antibiotics for a nasty infection recently. Definitely disrupted my digestion.