11

votes

Fecal transplant - the magic pill ?

Answered on August 19, 2014
Created November 12, 2010 at 9:29 AM

"Fecal bacteriotherapy, also known as fecal transfusion, fecal transplant, or human probiotic infusion (HPI), is a medical treatment for patients with pseudomembranous colitis (caused by Clostridium difficile), or ulcerative colitis which involves restoration of colon homeostasis by reintroducing normal bacterial flora from stool obtained from a healthy donor (Wikipedia).

This topic has been a great interest of mine since it seems that could help so many people so quickly.

This post is only part 1, collecting info on fecal transplant, while part 2 would focus on changing the world - DIY procedure.

Media coverage:

MedPage Today

NY Times ???That (her husbands microbes) community was able to function and cure her disease in a matter of days???

TheScientist "The results were nothing short of surprising, Borody said. Within days her colitis was gone, never to return."

Science blog

"Paleo" bloggers

Ayers (he talks more about it in the comments)

Perfect diet 1

Perfect diet 2

Forums

Part I analysis - 4 succesfull, one short (3 months) term and one failed.

Summary version - I did a fecal transplant, after 2 1/2 weeks I have seen amazing results. Worked better than any drug or diet modification

"Did just 2 doses (I was the donor - did it at home) and he noticed something different within 24 hours. Has been symptom free ever since. Feels great and can't believe how he has a normal life back!"

As for the "haters":

Get better health

"Our colons are not just full of bacteria, but they can also be populated with viruses, fungi, and protozoa"

Science based medicine

Science:

"One of the 16 survivors experienced a single recurrence of C. difficile colitis during 90???day follow???up. No adverse effects associated with stool treatment were observed."

"We report a case series (n = 7) where 100% clinical success was achieved in treating these individuals with up to 14 months of follow-up."

Microbiome profiles of recipients and donors post fecal transplantation for multiple recurrent CDI infection (PDF)

Fecal_Bacteriotherapy


Pros:

Effective "immediately"

Works

Cheap

Simple

Cons:

We can't detect all the possible "bad guys" in the poo

Any thoughts on this ?

84666a86108dee8d11cbbc85b6382083

(2399)

on September 07, 2013
at 01:28 AM

OK, it's not 100/100 (hey we even have people who got worse on Paleo) but still it can be THE magic for most. Paleo + this and 90% of people is healthy. I'll do a test of all the people from those threads but I'm sure that the success rate is over 70% despite the possibility of a "sloppy technique". I might be overhyping it but I truely believe that this could change thelives of many people. Thank you for your thoughts and congratulations on your remission.

4891acf703c4866885567a8d4ef9c5af

on February 02, 2012
at 02:16 AM

It can be administered via NG tube or if you're REALLY brave you can just drink the pooshake. The latter option is definitely not for the squeamish. I have a gag reflex that would make an adult film star proud and I still gagged a bit.

88905cfc5bb098ad3830671a1af373a8

(803)

on June 30, 2011
at 04:45 PM

I've read that it can, in fact, be taken orally.

B0454de6d4f4cdd9ca2e59021dc105bf

(606)

on June 30, 2011
at 09:40 AM

Ohhhh, it's *like* magic. Got it! I'm just teasing, NP :) From what I've read it really does seem pretty miraculous.

3c6b4eed18dc57f746755b698426e7c8

(5147)

on June 30, 2011
at 06:12 AM

Er, it is actually just like magic. Icky, maybe but it's reportedly incredibly effective. But I would consider that if I have IBDs like Crohn's or UC. I have chronic constipation issues but am not ready to try FT! I'll perhaps consider it after trying my nth probiotic!

06d21b99c58283ce575e36c4ecd4a458

(9948)

on November 15, 2010
at 02:45 AM

Chimps, gorillas, momkeys have been doing fecal transplants for a long time and it doesn't seem to bother them. A perfect DIY program. http://www.youtube.com/watch?v=I-fAQcx2jzk Loaded with Vitamin B-12. It is the perfect natural all organic remedy for vegans who do not consume any B-12 in their diet. http://freetheanimal.com/2010/11/go-vegan-the-new-vegan-diet-raw-and-all-natural-b12-solution.html

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 13, 2010
at 07:31 AM

Eating healthy is not a medical treatment and the concept of cutting out processed food and sugar is already generally accepted. The main 'weird' thing about paleo is cutting out the grains and since I don't see any special nutrition in those, I personally can find no reason why it would be prob. However, for the fecal issue, there are a lot more unknowns and you would also be introducing a very foriegn element into your body. So I consider it more drastic and more of an unknown than eating paleo.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 10:27 PM

The 18 patients didn't lose weight as predicted. So Ayer's quote is falsified; it's at best more complicated than that, at worst, it doesn't work that way. The failures I've read about have just been on various gut disorder message boards over the past few years. Some people rave about it others just see no effect. I believe a recent example was Kristina on the PaNu forum, who had been struggling with bloating and digestion problems for a long time and who got no relief from a fecal transplant (this was a couple months ago IIRC).

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 08:52 PM

Sorry, I accidentaly deleted the comment about Ayers. Ego at work :D "She noted, however, that there were no changes in patients' diets or their physical activity levels". Still I would expect a least some leptine help. I'll try to get the full paper so we can discuss this in further details. EDIT Ayers quote reposted:"I hope that you include in your future explanations the observations from fecal transplants between fat and lean individuals. Switch their gut flora and the lean gain weight while the fat lose weight. The gut flora dominate the metabolism".

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 08:41 PM

You can loose weight the easy way or the hard way. Leptin can be your friend or foe and I believe gut flora can help to befriend it. I would disagree about reruining your diet. People change, especially when sick. Also antibiotics treatments could fuck you up and you can't do nothing about it, good diet or not. In that case you're in for a looooong trip to healthy gut flora believe me. Can you point me to the places where you have read about this failures ? I need to collect as much data as possible to make this work.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 07:15 PM

To belabor the point a bit, read one of the articles you linked: http://www.the-scientist.com/news/display/57795/ It's decidedly mixed and every scientist involved is far more cautious than you are being in their predictions. It even counters Ayer's assertion of fat/lean with this section "They found that 18 obese patients with metabolic syndrome responded better to insulin and had lower triglycerides after they were infused with stool obtained from lean, healthy donors. The human subjects did not experience any change in weight, however..." So yeah. It works, but it's not magic.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 07:10 PM

Revolution, eh. I'm skeptical. It can treat gut dysbiosis and cure dysbiosis caused by one-time events. If you ruin your gut flora through poor diet you'll eventually re-ruin your gut flora. If gut flora dominate the metabolism, why can people lose weight WITHOUT a fecal transplant? I've read about this for years and read plenty of testimonies of it NOT working, so I think I'm working with a different set of biases. You seem very excited by the potential and so seem to be working from an opposing set of biases. Just 'cause you have a hammer doesn't mean my poo is a nail.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:27 PM

random note How many good clinical Paleo studies exist ? Tom Borody is Cordain both doing something so underrated that you want to cry. I hope I didn't make this sound like "Eat bad, do a fecal, eat bad further" type of text. This could be Paleo upgraded. I'm speculating that this would work on all gut flora effected problems. We don't know how deep the rabbit/gut hole goes but I'm with "deep". Check the Ayers quote in my comment to pfw. Also Stephane talks about the body setpoint and possible gut connections.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:24 PM

I'm not saying it will cure cancer but in theory it can cure everything that is related to gut health. Ayers quote "fecal transplants between fat and lean individuals. Switch their gut flora and the lean gain weight while the fat lose weight. The gut flora dominate the metabolism." That's fucking awesome. I don't want to fight over how great this might be but if this will work on a mainstream (even Paleo mainsteam) level I'm predicting a revolution.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:18 PM

I'm not saying it will cure cancer but in theory it can cure everything that is related to gut health :D Ayers quote "fecal transplants between fat and lean individuals. Switch their gut flora and the lean gain weight while the fat lose weight. The gut flora dominate the metabolism." That's fucking awesome. I don't want to fight over how great this might be but if this will work on a mainstream (even Paleo mainsteam) level I'm predicting a revolution.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:09 PM

Eva: Eenteric coating ? Also there is some kind of drug which temporately disables the stomach acid (will look for details when we come to the DIY part)

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:08 PM

*random note* How many good clinical Paleo studies exist ? I hope I didn't make this sound like "Eat bad, do a fecal, eat bad further" type of text. This could be Paleo upgraded. I'm speculating that this would work on all gut flora effected problems. We don't know how deep the rabbit/gut hole goes but I'm with "deep".

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 12, 2010
at 05:51 PM

Plus oral probiotics need to go through the stomach first and then the small intestine. Most likely won't make it to large instestine. To get to the large, you have to send it in from the other direction.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 02:54 PM

Er, I wouldn't get too excited. If you're talking specifically about bowel disorders it certainly has promise, but calling it a solution for all problems everywhere would be overreaching. There is no magic and there are no curealls, so thinking something is either is a good sign that you're oversimplifying.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 01:01 PM

OK it's not 100/100 (hey we even have people who got worse on Paleo) but still it can be THE magic for most. Paleo + this and 90% of people is healthy. I'll do a test of all the people from those threads but I'm sure that the success rate is over 70% despite the possibility of a "sloppy technique". I might be overhyping it but I truely believe that this could change thelives of many people. Thank you for your thoughts and congratulations on your remission. I was wondering did you ever think about this method ?

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 12:58 PM

OK it's not 100/100 (hey we even have people who got worse on Paleo) but still it can be THE magic for most. Paleo + this and 90% of people is healthy. I'll do a test of all the people from those threads but I'm sure that the success rate is over 70% despite the possibility of a "sloppy technique". I might be overhyping it but I truely believe that this could change thelives of many people. Thank you for your thoughts.

0bc6cbb653cdc5e82400f6da920f11eb

(19235)

on November 12, 2010
at 11:26 AM

Many types of bacteria in your gut cannot be grown outside of your gut and so cannot be put into probiotics. Most probiotics contain strains of bacteria that do not naturally live in your gut and soon die out.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:18 AM

Why: "What if, instead of re-constitituing healthy gut flora one species at a time (my edit:probiotics), you could simply take the entire fecal contents from a healthy person and use it to re-colonize your own gut--in other words, undergo a fecal transplant? Yes, it's like probiotics on steroids: getting an infusion of someone else's gut flora in order to re-establish a healthy gut ecology of your own, and squeeze out some potentially harmful organisms along the way."

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:14 AM

Cost: I assume it can't cost more than a few hundred bucks (probably a lot less) since the only costs are donor screening and the procedure itself. As for DIY, dirt cheap, main costs being the stool tests. That's the beauty of it. I predict/hope that we will develop a DIY procedure in a few weeks here at PaleoHacks. EDIT: It costs ~300$ in Australia.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:14 AM

Time: As quoted above "up to 14 months of follow-up" but if you want to get down and dirty (no pun intended) Healing well forums thread (linked above) has a bunch of people doing that and telling about it. One quote "My colon is doing great these days. I've been completely off all meds for the last 4 months or so." I have yet to throughly investigate that thread thought.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:10 AM

Time: As quoted above "up to 14 months of follow-up" but if you want to get down and dirty (no pun intended) Healing well forums thread (linked above) has a bunch of people doing that and telling about it. One quote "My colon is doing great these days. I've been completely off all meds for the last 4 months or so." I have yet to throughly investigate that thread thought. EDIT: It's ~ 300& in AUS.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:03 AM

Time: As quoted above "up to 14 months of follow-up" but if you want to get down and dirty (no pun intended) Healing zone forums thread (linked above) has a bunch of people doing that and telling about it. One quote "My colon is doing great these days. I've been completely off all meds for the last 4 months or so."

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:03 AM

Cost: I assume it can't cost more than a few hundred bucks (probably a lot less) since the only costs are donor screening and the procedure itself. As for DIY, dirt cheap, main costs being the stool tests. That's the beauty of it. I predict/hope that we will develop a DIY procedure in a few weeks here at PaleoHacks.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:03 AM

Why: Quoting Ayers "Use of probiotics is mostly cosmetic, and does not repair the loss of hundreds of species of gut bacteria killed by the antibiotics." Probiotics have like 8 type of bacteria which is nothing compared to the total count. We get A LOT more bacteria this way. Basically you are getting a new gut flora and gut flora is king :)

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7 Answers

5
4891acf703c4866885567a8d4ef9c5af

on February 02, 2012
at 02:12 AM

First post here so forgive any toe-stepping.

Heard about FT via the SciAm article for C diff but never considered using it for my UC (diagnosed in 1986, steroid dependent). Decided to try it after GI doc tried to force me to have surgery. Just did my second weekly enema last night. No major changes yet but pre-FT I only BM once a day and it was relatively normal. Hopefully FT will allow me to drop all my UC meds and still have normal BMs.

As for the concerns about donor stools harboring some unknown bad bugs, I'm willing to roll the dice. My donor was a 4 year old whose stools are a work of art and has more energy than anyone I know. If said donor has anything nasty hiding in the poo, it will be news to all the docs she sees regularly. I know there are unknown risks in this procedure but if I do nothing, my outcome is guaranteed to be surgery and that is something I want to avoid.

Time is not on my side and I can't wait for a bunch of hand-wringing scientists to do the work for me. Its too easy to get bogged down in possible risks and end up doing nothing. Scientific research usually progresses slowly and there's a good reason for that but I'm the lab rat on the receiving end of the enema bottle so I'm comfortable with said risks.

2
C4f1a0c70c4e0dea507c2e346c036bbd

on February 02, 2012
at 04:55 AM

I suspect it works because it bypass the stomach acid entirely. I'm curious on how it effects the mind too. I assume they place it up in the colon and not small intestine.

2
62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 12, 2010
at 05:55 PM

Very interesting but we need to see more clinical trials on this to see what the true success rate is. There may be many people who this did not work for who are just not interested in talking about it due to the 'ick' factor. We don't yet know which problems it does and does not work for. And it could be that without lifestyle changes, ie eating healthier, old problems could reoccur. However, I do think that research in this area has the potential to revolutionize common understanding of many problems, how they develop, and how they might be better cured.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:27 PM

random note How many good clinical Paleo studies exist ? Tom Borody is Cordain both doing something so underrated that you want to cry. I hope I didn't make this sound like "Eat bad, do a fecal, eat bad further" type of text. This could be Paleo upgraded. I'm speculating that this would work on all gut flora effected problems. We don't know how deep the rabbit/gut hole goes but I'm with "deep". Check the Ayers quote in my comment to pfw. Also Stephane talks about the body setpoint and possible gut connections.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:08 PM

*random note* How many good clinical Paleo studies exist ? I hope I didn't make this sound like "Eat bad, do a fecal, eat bad further" type of text. This could be Paleo upgraded. I'm speculating that this would work on all gut flora effected problems. We don't know how deep the rabbit/gut hole goes but I'm with "deep".

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 13, 2010
at 07:31 AM

Eating healthy is not a medical treatment and the concept of cutting out processed food and sugar is already generally accepted. The main 'weird' thing about paleo is cutting out the grains and since I don't see any special nutrition in those, I personally can find no reason why it would be prob. However, for the fecal issue, there are a lot more unknowns and you would also be introducing a very foriegn element into your body. So I consider it more drastic and more of an unknown than eating paleo.

1
990472da245e34f25e47af5d270b7a4b

(188)

on November 12, 2010
at 10:41 AM

We need to know more about this, but most of all, we need to be asking why it works and works so well. So many of us are using incredibly expensive supplements to fix our gut bacteria with very little change. I'm puzzled why this provides such immediate relief in so many cases. What are we missing?

Also, I'm curious how long the improvement lasts. I didn't see much info on this. I'd like to know how expensive the procedure is...and if insurance companies will be covering it.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:03 AM

Cost: I assume it can't cost more than a few hundred bucks (probably a lot less) since the only costs are donor screening and the procedure itself. As for DIY, dirt cheap, main costs being the stool tests. That's the beauty of it. I predict/hope that we will develop a DIY procedure in a few weeks here at PaleoHacks.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:14 AM

Time: As quoted above "up to 14 months of follow-up" but if you want to get down and dirty (no pun intended) Healing well forums thread (linked above) has a bunch of people doing that and telling about it. One quote "My colon is doing great these days. I've been completely off all meds for the last 4 months or so." I have yet to throughly investigate that thread thought.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:14 AM

Cost: I assume it can't cost more than a few hundred bucks (probably a lot less) since the only costs are donor screening and the procedure itself. As for DIY, dirt cheap, main costs being the stool tests. That's the beauty of it. I predict/hope that we will develop a DIY procedure in a few weeks here at PaleoHacks. EDIT: It costs ~300$ in Australia.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:09 PM

Eva: Eenteric coating ? Also there is some kind of drug which temporately disables the stomach acid (will look for details when we come to the DIY part)

62ed65f3596aa2f62fa1d58a0c09f8c3

(20807)

on November 12, 2010
at 05:51 PM

Plus oral probiotics need to go through the stomach first and then the small intestine. Most likely won't make it to large instestine. To get to the large, you have to send it in from the other direction.

06d21b99c58283ce575e36c4ecd4a458

(9948)

on November 15, 2010
at 02:45 AM

Chimps, gorillas, momkeys have been doing fecal transplants for a long time and it doesn't seem to bother them. A perfect DIY program. http://www.youtube.com/watch?v=I-fAQcx2jzk Loaded with Vitamin B-12. It is the perfect natural all organic remedy for vegans who do not consume any B-12 in their diet. http://freetheanimal.com/2010/11/go-vegan-the-new-vegan-diet-raw-and-all-natural-b12-solution.html

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:03 AM

Why: Quoting Ayers "Use of probiotics is mostly cosmetic, and does not repair the loss of hundreds of species of gut bacteria killed by the antibiotics." Probiotics have like 8 type of bacteria which is nothing compared to the total count. We get A LOT more bacteria this way. Basically you are getting a new gut flora and gut flora is king :)

0bc6cbb653cdc5e82400f6da920f11eb

(19235)

on November 12, 2010
at 11:26 AM

Many types of bacteria in your gut cannot be grown outside of your gut and so cannot be put into probiotics. Most probiotics contain strains of bacteria that do not naturally live in your gut and soon die out.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:03 AM

Time: As quoted above "up to 14 months of follow-up" but if you want to get down and dirty (no pun intended) Healing zone forums thread (linked above) has a bunch of people doing that and telling about it. One quote "My colon is doing great these days. I've been completely off all meds for the last 4 months or so."

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:18 AM

Why: "What if, instead of re-constitituing healthy gut flora one species at a time (my edit:probiotics), you could simply take the entire fecal contents from a healthy person and use it to re-colonize your own gut--in other words, undergo a fecal transplant? Yes, it's like probiotics on steroids: getting an infusion of someone else's gut flora in order to re-establish a healthy gut ecology of your own, and squeeze out some potentially harmful organisms along the way."

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 11:10 AM

Time: As quoted above "up to 14 months of follow-up" but if you want to get down and dirty (no pun intended) Healing well forums thread (linked above) has a bunch of people doing that and telling about it. One quote "My colon is doing great these days. I've been completely off all meds for the last 4 months or so." I have yet to throughly investigate that thread thought. EDIT: It's ~ 300& in AUS.

0
4145b36f1488224964edac6258b75aff

(7821)

on September 07, 2013
at 12:44 AM

It doesn't always work. This is a common last resort sort of maneuver for people with UC/Crohn's and while it works for some for others it does nothing, or even, to quote someone in one of those threads, causes a flare:

Hey LuckyLindy-- that is very encouraging, and I am very happy for you! I tried it with my wife's stool as well- I even spent $1500 having her tested first(even though it seeemd silly to since we share germs- but just wanted to rule out anything that might worsen my UC). In my case, I actually flared after trying it ... somehow or another her stool must have been incompatable. Like you I didn't do the antibiotics or fiber part of the regimen. Anyway, early good results for you indicate you may have found the magic bullet and I certainly hope so. Thanks for sharing.

It's not magic but it is certainly an interesting option.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 07:10 PM

Revolution, eh. I'm skeptical. It can treat gut dysbiosis and cure dysbiosis caused by one-time events. If you ruin your gut flora through poor diet you'll eventually re-ruin your gut flora. If gut flora dominate the metabolism, why can people lose weight WITHOUT a fecal transplant? I've read about this for years and read plenty of testimonies of it NOT working, so I think I'm working with a different set of biases. You seem very excited by the potential and so seem to be working from an opposing set of biases. Just 'cause you have a hammer doesn't mean my poo is a nail.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 01:01 PM

OK it's not 100/100 (hey we even have people who got worse on Paleo) but still it can be THE magic for most. Paleo + this and 90% of people is healthy. I'll do a test of all the people from those threads but I'm sure that the success rate is over 70% despite the possibility of a "sloppy technique". I might be overhyping it but I truely believe that this could change thelives of many people. Thank you for your thoughts and congratulations on your remission. I was wondering did you ever think about this method ?

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 08:41 PM

You can loose weight the easy way or the hard way. Leptin can be your friend or foe and I believe gut flora can help to befriend it. I would disagree about reruining your diet. People change, especially when sick. Also antibiotics treatments could fuck you up and you can't do nothing about it, good diet or not. In that case you're in for a looooong trip to healthy gut flora believe me. Can you point me to the places where you have read about this failures ? I need to collect as much data as possible to make this work.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 10:27 PM

The 18 patients didn't lose weight as predicted. So Ayer's quote is falsified; it's at best more complicated than that, at worst, it doesn't work that way. The failures I've read about have just been on various gut disorder message boards over the past few years. Some people rave about it others just see no effect. I believe a recent example was Kristina on the PaNu forum, who had been struggling with bloating and digestion problems for a long time and who got no relief from a fecal transplant (this was a couple months ago IIRC).

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 02:54 PM

Er, I wouldn't get too excited. If you're talking specifically about bowel disorders it certainly has promise, but calling it a solution for all problems everywhere would be overreaching. There is no magic and there are no curealls, so thinking something is either is a good sign that you're oversimplifying.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:18 PM

I'm not saying it will cure cancer but in theory it can cure everything that is related to gut health :D Ayers quote "fecal transplants between fat and lean individuals. Switch their gut flora and the lean gain weight while the fat lose weight. The gut flora dominate the metabolism." That's fucking awesome. I don't want to fight over how great this might be but if this will work on a mainstream (even Paleo mainsteam) level I'm predicting a revolution.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 12:58 PM

OK it's not 100/100 (hey we even have people who got worse on Paleo) but still it can be THE magic for most. Paleo + this and 90% of people is healthy. I'll do a test of all the people from those threads but I'm sure that the success rate is over 70% despite the possibility of a "sloppy technique". I might be overhyping it but I truely believe that this could change thelives of many people. Thank you for your thoughts.

4145b36f1488224964edac6258b75aff

(7821)

on November 12, 2010
at 07:15 PM

To belabor the point a bit, read one of the articles you linked: http://www.the-scientist.com/news/display/57795/ It's decidedly mixed and every scientist involved is far more cautious than you are being in their predictions. It even counters Ayer's assertion of fat/lean with this section "They found that 18 obese patients with metabolic syndrome responded better to insulin and had lower triglycerides after they were infused with stool obtained from lean, healthy donors. The human subjects did not experience any change in weight, however..." So yeah. It works, but it's not magic.

84666a86108dee8d11cbbc85b6382083

(2399)

on September 07, 2013
at 01:28 AM

OK, it's not 100/100 (hey we even have people who got worse on Paleo) but still it can be THE magic for most. Paleo + this and 90% of people is healthy. I'll do a test of all the people from those threads but I'm sure that the success rate is over 70% despite the possibility of a "sloppy technique". I might be overhyping it but I truely believe that this could change thelives of many people. Thank you for your thoughts and congratulations on your remission.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 06:24 PM

I'm not saying it will cure cancer but in theory it can cure everything that is related to gut health. Ayers quote "fecal transplants between fat and lean individuals. Switch their gut flora and the lean gain weight while the fat lose weight. The gut flora dominate the metabolism." That's fucking awesome. I don't want to fight over how great this might be but if this will work on a mainstream (even Paleo mainsteam) level I'm predicting a revolution.

84666a86108dee8d11cbbc85b6382083

(2399)

on November 12, 2010
at 08:52 PM

Sorry, I accidentaly deleted the comment about Ayers. Ego at work :D "She noted, however, that there were no changes in patients' diets or their physical activity levels". Still I would expect a least some leptine help. I'll try to get the full paper so we can discuss this in further details. EDIT Ayers quote reposted:"I hope that you include in your future explanations the observations from fecal transplants between fat and lean individuals. Switch their gut flora and the lean gain weight while the fat lose weight. The gut flora dominate the metabolism".

0
62f89aa727cf3ce77c36651347cabc14

(884)

on June 30, 2011
at 07:45 PM

I've been considering it, after having to take a course of antibiotics for a nasty infection recently. Definitely disrupted my digestion.

0
B0454de6d4f4cdd9ca2e59021dc105bf

on June 30, 2011
at 06:06 AM

In answer to the OP's question. No, fecal transplant is neither magic nor a pill (can you imagine? yuck)!

3c6b4eed18dc57f746755b698426e7c8

(5147)

on June 30, 2011
at 06:12 AM

Er, it is actually just like magic. Icky, maybe but it's reportedly incredibly effective. But I would consider that if I have IBDs like Crohn's or UC. I have chronic constipation issues but am not ready to try FT! I'll perhaps consider it after trying my nth probiotic!

88905cfc5bb098ad3830671a1af373a8

(803)

on June 30, 2011
at 04:45 PM

I've read that it can, in fact, be taken orally.

B0454de6d4f4cdd9ca2e59021dc105bf

(606)

on June 30, 2011
at 09:40 AM

Ohhhh, it's *like* magic. Got it! I'm just teasing, NP :) From what I've read it really does seem pretty miraculous.

4891acf703c4866885567a8d4ef9c5af

on February 02, 2012
at 02:16 AM

It can be administered via NG tube or if you're REALLY brave you can just drink the pooshake. The latter option is definitely not for the squeamish. I have a gag reflex that would make an adult film star proud and I still gagged a bit.

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