2

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Is Astaxanthin worth supplementing? Really?

Answered on December 07, 2014
Created April 20, 2013 at 7:46 PM

Hello,

Is Astaxanthin worth taking?

I hear so many positive effects and results from it about reducing sun spots, improving vision and etc.

And plus its antioxidants effects...

So what do you guys think?...(Wild salmon is expensive where i live)

Thanks

6d64cd6dc98d6ab763bd03678a317964

(2177)

on April 22, 2013
at 12:55 AM

I am taking it now. lol.

7841848bd0c27c64353c583fb7971242

(7275)

on April 21, 2013
at 01:19 PM

That would be second hand experience, since your friends took it, but you haven't yet.

Be1dbd31e4a3fccd4394494aa5db256d

(17969)

on April 21, 2013
at 01:06 AM

also if you have alcoholic rats you should get them on it ASAP!

089dd41b18fbb95ebb5347cded708d98

(5635)

on April 21, 2013
at 12:49 AM

ha yes, matt! it wasn't cheap- that's for sure.

7e1433afbb06c318c4d90860d493c49d

(5959)

on April 20, 2013
at 10:09 PM

Same here, and I used a 4mg *and* a 12mg per day.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on April 20, 2013
at 09:54 PM

Sure you did... that pocketbook felt lighter, didn't it? ;)

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6 Answers

best answer

5
Be1dbd31e4a3fccd4394494aa5db256d

(17969)

on April 21, 2013
at 01:04 AM

Seems like it's one of the better antioxidants in some cases, but honestly the literature is a bit ambiguous at this point; like it was supposed to improve endurance but a newer study showed that it didn't:

http://www.ncbi.nlm.nih.gov/pubmed/23274592 No http://www.ncbi.nlm.nih.gov/pubmed/21984399 Yes http://www.ncbi.nlm.nih.gov/pubmed/17015959 Yes in mice

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845588/

"Plasma astaxanthin increased (P < 0.01) dose-dependently after 4 or 8 wk of supplementation. Astaxanthin decreased a DNA damage biomarker after 4 wk but did not affect lipid peroxidation. Plasma C-reactive protein concentration was lower (P < 0.05) on wk 8 in subjects given 2 mg astaxanthin. Dietary astaxanthin stimulated mitogen-induced lymphoproliferation, increased natural killer cell cytotoxic activity, and increased total T and B cell subpopulations, but did not influence populations of Thelper, Tcytotoxic or natural killer cells. A higher percentage of leukocytes expressed the LFA-1 marker in subjects given 2 mg astaxanthin on wk 8. Subjects fed 2 mg astaxanthin had a higher tuberculin response than unsupplemented subjects. There was no difference in TNF and IL-2 concentrations, but plasma IFN-?? and IL-6 increased on wk 8 in subjects given 8 mg astaxanthin."

In a good quality trial in humans it significantly reduced inflammation and DNA damage and improved immune function. Only 2mg was needed and more wasn't really better. In fact more might be harmful, though I would really like to talk to someone who really knows their stuff on this issue. TNA and Il-6 are two cytokines that can be pathological and cause insulin resistance and stuff if they signal too heavily. High levels of them are risk factors for diabetes and heart disease, and while 2mg of astaxanthin appeared to be "beneficial" (if less in blood is necessarily better) 8mg a day was harmful (if more in the blood is necessarily worse) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845588/table/T3/

So it appears to protect tissues, eyes, and organs in other studies, and it looks to have some promise at low doses, but I'm not so sure about high doses. That might actually explain the discrepancies between the studies, the one that showed benefit to endurance used 4mg and the one that didn't used 20mg. But this is speculation.

I personally take 2mg myself, I figure I probably don't have anything to lose except a few dollars a month and I have potentially quite a bit to gain if the DNA damage paper is legit. I didn't see any dramatic changes in health from it but then again I already make a lot of my own antioxidants in my body and I eat quite a bit of pasta sauce rich in other carotenoids.

Needs more research (this seems to be a perpetual theme in supplement science :D)

Be1dbd31e4a3fccd4394494aa5db256d

(17969)

on April 21, 2013
at 01:06 AM

also if you have alcoholic rats you should get them on it ASAP!

4
089dd41b18fbb95ebb5347cded708d98

(5635)

on April 20, 2013
at 07:55 PM

i never really noticed a difference taking it. i was using a 4mg capsule and then bumped it up to 12 mg capsules. still no improvement.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on April 20, 2013
at 09:54 PM

Sure you did... that pocketbook felt lighter, didn't it? ;)

089dd41b18fbb95ebb5347cded708d98

(5635)

on April 21, 2013
at 12:49 AM

ha yes, matt! it wasn't cheap- that's for sure.

7e1433afbb06c318c4d90860d493c49d

(5959)

on April 20, 2013
at 10:09 PM

Same here, and I used a 4mg *and* a 12mg per day.

2
89985542ffc00c296552951369fe809a

on April 21, 2013
at 03:00 AM

I get Astaxanthin from wild salmon, that's good enough for me! You could also take KRILL... You will get astazanthin and healthy fats!

1
8292546789ca48c32ead34c6e884d059

on April 20, 2013
at 11:12 PM

I had good results taking it for sunburns and preventing them. I look forward to retesting this this year.

I am white as plain-paper.

0
E24390f6d880f9144cdf7ab13220a84a

(3)

on December 07, 2014
at 10:59 AM

Well, this is a pretty depressing post since I was taking 12 mg tablets three times a day.   I guess that isn't going to work unless I want to be on the leading edge (I don't).

I have not had any adverse reactions, nor have I seen any heart disease or worsening of prediabetes.  So it is not having the particular adverse reactions you cite, in me.

Does anyone know what the maximum doses administered in human studies have been?

0
6d64cd6dc98d6ab763bd03678a317964

(2177)

on April 21, 2013
at 03:33 AM

I have first hand experience with Astaxanthin. A friend of mine who is pale white has extreme sun sensitivity. 10 minutes in a tanning booth and she will get burned. She was going on vacation and wanted to tan so I told her to take 12mg astaxanthin. After taking it for 2 weeks she did 10 minutes in the tanning booth. Didn't feel the burn, so she did 10 more, and then 10 more. 30 minutes total and absolutely no burn whatsoever. I'm

Another person I told to take it because they were getting eye fatigue and blood shot eyes from staring at a computer screen all day. Within a week, astaxanthin had fixed his problem.

I'm going to be testing this out on myself this year as I had 2nd degree burns last year....for now I am a believer.

6d64cd6dc98d6ab763bd03678a317964

(2177)

on April 22, 2013
at 12:55 AM

I am taking it now. lol.

7841848bd0c27c64353c583fb7971242

(7275)

on April 21, 2013
at 01:19 PM

That would be second hand experience, since your friends took it, but you haven't yet.

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