I got my bloodwork redone. I did it first in July before I went paleo. Below the development in the past 5 months, ending with my layman conclusion. Any help in interpreting the results, especially testosterone and cholesterol levels, would be much appreciated!
I'm 36-year-old male, 183cm/81kg/16% bf, lift weights 3 times a week, office job. On LeanGains body recomposition diet for 3 months, and I started intermittent fasting in February: 16 hours off, 8 hours on, 7 days a week.
Note the units used! Not everything was tested in July. Guidance ranges are given by the lab.
July 2011 December 2011 guidance Total Cholesterol mmol/l 5.6 5.94 2.5 - 6.5 Triglycerides mmol/l 0.62 0.68 0 - 2 HDL mmol/l 1.68 1.38 0.9 - 3.0 LDL mmol/l 3.7 4.25 0 - 3.5 HDL-ratio mmol/l 3.3 4.3 0 - 5.0 Testosterone nmol/l 16 20 9 - 35 SHBG nmol/l 59 10 - 70 Free Testosterone (FAI) index 0.34 0.2 - 1.0 25-OH Vitamine D nmol/l 104 119 50 - 185 Hemoglobine mmol/l 9.2 8.4 - 10.9 Hematocriet l/l 0.44 0.42 - 0.51 Creatinine umol/l 83 62 - 115 eGFR (MDRD-4) ml/min >90 60 ALAT (SGPT) U/l 31 0 - 41 Glucose mmol/l 4.7 3.5 - 11.1 TSH mU/l 2.4 0.35 - 4.94
Cholesterol converted to mg/dL:
Total Cholesterol 228 mg/dL
HDL (High density lipoprotein) 53 mg/dL
LDL (Low density lipoprotein) 164 mg/dL
Triglycerides 60 mg/dL
This Cholesterol Calculator gives me:
Your Total Cholesterol of 228 is BORDERLINE Your LDL of 164 is HIGH RISK Your HDL of 53 is NORMAL Your Triglyceride level of 60 is NORMAL
RATIOS: Your Total Cholesterol/HDL ratio is: 4.30 - (preferably under 5.0, ideally under 3.5) GOOD [this increased from 3.32 in July]
Your HDL/LDL ratio is: 0.323 - (preferably over 0.3, ideally over 0.4) GOOD [0.455 in July]
Your triglycerides/HDL ratio is: 1.132 - (preferably under 4, ideally under 2) IDEAL [0.615 in July]
My interpretation: I'm ignoring total cholesterol, triglycerides and HDL/LDL, and only looking at ratios as they seem to be the ones that matter. While total cholesterol to HDL ratio is still within guidelines, it has deteriorated. Same with triglycerides / HDL and HDL/LDL; it's going in the wrong direction.
So cholesterol is ok, but is headed in the wrong direction. Need to fix.
Testosterone has improved since July. Free Testosterone calculation is Free Androgen Index, which is an invalid method according to wikipedia. This means, I believe, that the results above don't show a valid free testosterone figure, which would be needed for an accurate assessment of my test levels.
Nevertheless, my SHBG is at the high end of guidance, and high SHBG implies low free test according to Robb Wolf. Need to fix free test levels.
D-vitamin level is good, my current supplementation level seems to work (3580 IU per day, from cod liver oil and separate D-vitamin supplement).
Not sure if the other items tell anything worthy of intervention.
asked byWisper (2957)
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on December 19, 2011
at 12:14 PM
Your TSH is pretty high
"Over a period of several years, I never saw a person whose TSH was over 2 microIU/ml who was comfortably healthy, and I formed the impression that the normal, or healthy, quantity was probably something less than 1.0. " http://raypeat.com/articles/articles/hypothyroidism.shtml
on December 21, 2011
at 08:33 PM
I wouldn't sweat the lipids at all. Your ratio is great and your reported LDL is likely wrong.
"In patients with low serum triglyceride and undesirably high total cholesterol levels, Friedewald equation may overestimate low-density lipoprotein cholesterol concentration and it should be either directly assayed or be calculated by a modified Friedewald equation."
on December 21, 2011
at 05:18 PM
Honestly, I don't think the changes look particularly significant, and are well in a good range. Looking at triglycerides and HDL in particular (as they won't have measured LDL) you look good. Because of the numbers involved small changes can seem like a big swing, but that's not really the best way to look at it.
Keep an eye on things if you like, but I don't think there's anything there that suggests you would necessarily do any better by changing something.
on December 21, 2011
at 05:15 PM
You cholesterol numbers look fine to me. Your HDL is almost equal to your trigs, which is excellent. It may have gone "in the wrong direction" since July, but only very slightly and I don't see much to be alarmed about here.
Your TSH is slightly elevated, as Cliff has already noted, so you may want to have them run your full thyroid numbers for a better picture of your thyroid health.