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Do BCAA's stop the autophagy process?

Answered on December 01, 2017
Created November 16, 2012 at 3:12 PM

The BCAA supplement i am taking has approximently 15 calories per serving 2 servings. Would this effect my insulin sensitivty and autophagy if i decide to take one in the morning? i read on artciles that protein should be ingested after a certain amount especially on IF in a consistent maner. I checked around and found different answers but with not much detail as to why it does orr dosen't. My eating window is from 12-8pm on most days except friday. I also try to do the Paleo diet with this to maximize results in terms of health and fitness So if i take amino acids around 7 am would that have broken my fast as well as autophagy state? or is it broken when i take in a signicant amount of calories?

(I also take the supplements as a preworkout as well.)

Here is the link to the supplement's nutrional facts:

http://www.bodybuilding.com/store/tl/amino.html?MCID=CG-PLA-US&mr%3AtrackingCode=1DF6AED0-BC1A-E111-973E-001517384908&mr%3AreferralID=NA&mr%3AadType=pla&mr%3Aad=16629521226&mr%3Akeyword=&mr%3Amatch=&mr%3Afilter=41327410386

Thanks, Nick

2578d76e50aec56d2233f1e39553767c

(0)

on December 01, 2017
at 04:08 PM

If doing a 16/8 IF schedule, one shouldn't really conceern them self with the process of autophagy. The "sweet spot", of autophagy, is not triggered unitl about 16 hours. So, if the fast last less than 16 hours the benefits of autophagy would not be very great. Also, a consideration ust be made for when, chronologically, the fast is taking place. In this case, considerable hours of fasting are occuring while sleeping, which would also impact the autphagy process. 

 

96440612cf0fcf366bf5ad8f776fca84

(19413)

on November 16, 2012
at 09:34 PM

Or you can try taking the BCAAs later in the day if you skip breakfast for IF.

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3 Answers

2
64433a05384cd9717c1aa6bf7e98b661

(15236)

on November 16, 2012
at 03:15 PM

Yeah it does stop (or at least reduce) autophagy and some of the benefits of your fast. I think the idea behind taking those on the leangains method is it's a way to preserve muscle mass while calorie restricting.

Depending on your goals and body type, I would try skipping them and see how you feel.

96440612cf0fcf366bf5ad8f776fca84

(19413)

on November 16, 2012
at 09:34 PM

Or you can try taking the BCAAs later in the day if you skip breakfast for IF.

0
2578d76e50aec56d2233f1e39553767c

on December 01, 2017
at 04:10 PM


Tranz4mer

(0)
on less than a minute ago

 

If doing a 16/8 IF schedule, one shouldn't really conceern them self with the process of autophagy. The "sweet spot", of autophagy, is not triggered unitl about 16 hours. So, if the fast last less than 16 hours the benefits of autophagy would not be very great. Also, a consideration ust be made for when, chronologically, the fast is taking place. In this case, considerable hours of fasting are occuring while sleeping, which would also impact the autphagy process. 

0
68294383ced9a0eafc16133aa80d1905

(5795)

on November 30, 2012
at 04:51 PM

There is not a definitive YES or NO answer to this. On one hand, the presence of an Insulin response WILL interrupt Autophagy. The ingestion of BCAA's WILL stimulate an acute release of Insulin. However, we know that BCAA's effect on Insulin is very short, occuring approximately 15-45 minutes after ingestion. This is going to be even faster if delivered in a liquid or dissolved form. With that said, BCAA's, when consumed by themselves and without a meal containing essential amino acids in whole food form, and EAA supplement or any combo of protein/carbohydrate is going to have very little impact on overall Insulin secretion.

Now, does this mean by using BCAA's during a fast is more optimal for Autophagy than a complete fast? No. It's definitely not because of what I posted above. However, it's still something that would allow you to get the majority of the intended benefits of fasting, even with the BCAA's. Like someone else posted, using it as a way to spare muscle is the most common use. This is why someone using a lower carbohydrate template to lose body fat might want to consider using BCAA's. Same for Autophagy. The progress and speed of the gains might be slower, but you're not nullifying all benefits by taking BCAA's.

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