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Cholesterol LDL went crazy now trying Plan B what do you think CURE Leptin Cure Diabetes Hypothyroidism.. ¿¿¿

Answered on December 29, 2013
Created December 28, 2013 at 1:58 AM

This is the short version edited for clarity :)

Paleo diet in 2012 did not work for me..that was plan A. It was high fat ,med protein low carb

my total cholesterol sky rocketed to 14 mmol/l = 541.37664 m

I have type 2 diabetes controlled by diet only,after initial diagnosis 5 years ago

I also have hypothyroidism, diagnosed a year after my diabetes. I take T4 and .25mcg its basically the minimum doseage.

I tried Paleo... to lose 8 kilos weight , and improve my blood sugars.

Before Paleo my total cholesterol was 6.2, hdl was low and trig high and ldl high, bad signs basically

Blood results after being on paleo circa 1 year below, i lost the 8 kilo but ..

cholesterol total 9.7 mmol USA 375.<<< yikes

triglycerides 1.03 91 USA

hdl 1.59 USA 61

LDL 7.6 USA USA 293

so i stopped almost all fat from meat ,next test in 3 months showed my total cholesterol skyocketed again especially LDL

Total cholesterol 14 mmol/l = 541.37664 mg/dl I knew something was wrong....

I thought Perhaps liver purging but for this long (4 months)naaah.

Throughout my thyroid was fine..

I never got my LDL parsed not possible in Ireland .

regards to my thyroid

Antibody tests look good so unlikely it is hashimitos but perhaps a conversion issue T4 to T3 , based on this I expect it is fine to take iodine..??

TPO AB 7 range is 0 -35 quite good.

Because my cholesterol went beserk

I stopped the paleo "Plan A " and went back to a low carb diet I take a statin now at a minimal dose .

(yes I have weighed up the pros and cons of statins and expect in certain scenarios they are a temporary solution, stats do raise vitamin d too :)

Any ideas for my new Plan B sure would be welcome.

My goals are to lower visceral fat and "fix leptin"

Reverse my diabets and hypthyroidism too , and come of the statin eventually, and the thyroid meds.

Not asking for much eh :)

Now When I reflect on my high LDL it could have been my liver parsing, but this time I will do a keto diet higher in protein than fat , (So I can eliminate the fat intake from my scenario) so hopefully my liver purges and I loose my visceral fat, too...

I have no idea how ,long it takes for a liver to purge any ideas ?

My new "plan B" is very low carb under 25 daily , lowish fat higher protein. Fairly hard exercise.

I also do free stading squats daily til my thighs burn

My current status I need to loose another 4 kilos again, I weigh circa 84 kilos .I put a little on in the last year as I stopped my exercise.

On my new Plan B I have already lost circa 3 kilos in 6 weeks I am in mild ketosis acording to the ketostix.

hmmmm .....About Visceral fat and insulin resistance

Carrying a high amount of visceral fat is known to be associated with insulin resistance, which can lead to glucose intolerance and type 2 diabetes. Researchers have found that visceral secretes a protein called retinol-binding protein 4 (RBP4) which has been shown to increase resistance to insulin.

Below the Newcastle diet circa 600 calories from drinks and 200 from vegetables this is another option to me..

But I presume such a drastic diet may cause issues with my hypothyroidism.

Diabetes reversed below,

http://www.ncl.ac.uk/press.office/press.release/item/diet-reverses-type-2-diabetes

My Regime

Under 1400 calories daily ketogenic diet

The daily calorie intake is not to exceed 1400 calorie daily max. so it is a ketogenic diet

supplements I am taking.

selenium , magnesium , k2, multi vit B , B12, chromium GTF, Zinc piccolinate,vitd25, probiotics, iodine in the form of Iodrol,krill oil.

Ubiquinol. << as I am taking a statin for the time being..

And I eat lambs lever circa 2-3 times monthly

Exercise. daily

Ideas and suggestions welcome

3ce6a0d24be025e2f2af534545bdd1d7

(26217)

on December 29, 2013
at 02:51 PM

Vegetarian is not high carb. It's only high carb if you make it.

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 11:19 PM

Matt weight is there diet too also activity ..gender and age is not there Male 50.

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 10:30 PM

Thanks CDone but generally vegetarian meals a big no no for diabetics too many carbs, but fish a good point I eat plenty of wild salmon .The only vegetarian meal i have is my special exception Bitter gourd for its insulin properties.

thanks chessguy

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 05:49 PM

I'd be weary of ruling out things prematurely given you're in the 99th percentile of cholesterol readings.

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 05:20 PM

Hi Matt, ruled that out for now

My family do not have cholesterol issues, also I do not expect I am Apoe E 2/4 as my triglycerides were well maintained on the paleo diet..even when the LDL soared.

If it was genetics my triglycerides would also have been elevated,

As Bukowski mentioned Endotoxin i rule that out too as my HDL is quite good.

chessguy

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 04:59 PM

Ditch the supplements until diet is in line. Supplements are there not as medicine but as filling in gaps in diet.

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 04:59 PM

Supplements are harmful, give me a break. They're a waste of time, but harmful? Pfft. Irritated gut from fat? Endotoxins? Silliness.

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 04:55 PM

As much information you have there, there's more relevant stuff: typical diet, sex, age, weight, height, etc... activity level…

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 02:35 PM

Edited for clarity :)

Medium avatar

(238)

on December 28, 2013
at 03:57 AM

My one thought is that is a very difficult post to wade through, either reformat or drop some superflous info so it can be read.

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 02:02 AM

I have uploaded it here as an attatchment

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 02:00 AM

it has not formatted correctly looks awful to read

  • Bdcb4ecc75f7b6867b785a7eadf25ece

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9 Answers

0
Bdcb4ecc75f7b6867b785a7eadf25ece

on December 29, 2013
at 10:50 PM

hi

just found this site

this is quite enlightening especially for diabetics and people with cholesterol issues on a paleo diet..

>>>>> Central Obesity' part 1

http://www.maxwettsteinfitness.com/Library/Belly%20fat.htm

I am quite surprised that a few of Pro;s writing books and holding seminars etc did not highlight visceral fat ,

as a a cause for LDL soaring, when on a low carb high fat diet.

0
Bdcb4ecc75f7b6867b785a7eadf25ece

on December 29, 2013
at 09:38 PM

fredmull thanks for the link it was interesting reading..

0
4610451431ec7155c87a5698be682a95

(1122)

on December 29, 2013
at 01:12 AM

http://paleohacks.com/questions/86227/does-zero-carb-really-have-to-be-a-high-fat-diet.html

If I were in your position I'd try this protocol. However, I'm not a doctor, nor do I play one on tv.

0
Bdcb4ecc75f7b6867b785a7eadf25ece

on December 29, 2013
at 12:44 AM

just found this

at Harvard edu

http://www.health.harvard.edu/fhg/updates/Abdominal-fat-and-what-to-do-about-it.shtml

Research suggests that fat cells — particularly abdominal fat cells — are biologically active. It’s appropriate to think of fat as an endocrine organ or gland, producing hormones and other substances that can profoundly affect our health. Although scientists are still deciphering the roles of individual hormones, it’s becoming clear that excess body fat, especially abdominal fat, disrupts the normal balance and functioning of these hormones.

Scientists are also learning that visceral fat pumps out immune system chemicals called cytokines — for example, tumor necrosis factor and interleukin-6 — that can increase the risk of cardiovascular disease. These and other biochemicals are thought to have deleterious effects on cells’ sensitivity to insulin, blood pressure, and blood clotting.

One reason excess visceral fat is so harmful could be its location near the portal vein, which carries blood from the intestinal area to the liver. Substances released by visceral fat, including free fatty acids, enter the portal vein and travel to the liver, where they can influence the production of blood lipids. Visceral fat is directly linked with higher total cholesterol and LDL (bad) cholesterol, lower HDL (good) cholesterol, and insulin resistance.

chessguy

0
Bdcb4ecc75f7b6867b785a7eadf25ece

on December 28, 2013
at 10:48 PM

Thanks CDone but generally vegetarian meals a big no no for diabetics too many carbs, but fish a good point I eat plenty of wild salmon .The only vegetarian meal i have is my special exception Bitter gourd for its insulin properties.

I really do believe visceral fat is the key to leptin and diabetes,

hmmmm .....About Visceral fat and insulin resistance.

Carrying a high amount of visceral fat is known to be associated with insulin resistance, which can lead to glucose intolerance and type 2 diabetes. Researchers have found that visceral secretes a protein called retinol-binding protein 4 (RBP4) which has been shown to increase resistance to insulin.

I read the links as a refresher I read similar on the quilts site too

thanks chessguy

3ce6a0d24be025e2f2af534545bdd1d7

(26217)

on December 29, 2013
at 02:51 PM

Vegetarian is not high carb. It's only high carb if you make it.

0
3ce6a0d24be025e2f2af534545bdd1d7

(26217)

on December 28, 2013
at 07:50 PM

Disclaimer: I am not a doctor. I would work with your doctor before implementing any of these recommendations. I would also try someone with a history of helping people with cholesterol. Some like (and it hurts me to type this) Chris Kresser (http://chriskresser.com/announcing-the-high-cholesterol-action-plan | http://robbwolf.com/wp/wp-content/uploads/2012/09/Paleo-Solution-151.pdf).

My thoughts:

First: Implement a low-impact exercise plan. Run three times a week, do body weight two times a week. Being consistent is absolutely essential. Work up to where you are doing 30-45 minutes of aerobic exercise three times a week, then start to implement some speed play in two of those workouts.

Second: Reduce meat consumption, up vegetable consumption. A little meat can go a long way (4-6oz is sufficient). For dinner -- 1 Fish, 1 Shell fish, 2 Meat, 1 Offal meals per week. The other two days should be vegetarian. Your other meals should be largely vegetarian with a few eggs per week. Olive oil and vinegar are a good dressing.

Third: Relax -- 8 hours of sleep each night, a bit of meditation/reading/etc before bed to reduce stress.

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 10:30 PM

Thanks CDone but generally vegetarian meals a big no no for diabetics too many carbs, but fish a good point I eat plenty of wild salmon .The only vegetarian meal i have is my special exception Bitter gourd for its insulin properties.

thanks chessguy

0
32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 04:54 PM

Not a fan of blaming genetics first, but have you been checked for familial hypercholesterolemia? You were on the high end of cholesterol when you started and a high-fat/high-cholesterol diet may have been throwing gasoline on that fire.

The answer in that case: lower-fat diet and statins.

Bdcb4ecc75f7b6867b785a7eadf25ece

(38)

on December 28, 2013
at 05:20 PM

Hi Matt, ruled that out for now

My family do not have cholesterol issues, also I do not expect I am Apoe E 2/4 as my triglycerides were well maintained on the paleo diet..even when the LDL soared.

If it was genetics my triglycerides would also have been elevated,

As Bukowski mentioned Endotoxin i rule that out too as my HDL is quite good.

chessguy

0
Bdcb4ecc75f7b6867b785a7eadf25ece

on December 28, 2013
at 02:34 PM

Bukowski

High carb low fat would raise my blood sugars, i am diabetic type 2.

The iodine and krill oil are new ideas, I am adopting,the low calorie keto diet is in a direct bid to reduce visceral fat and fat in the liver,the exercise I do is to ensure my muscles have increased insulin sensitivity.

This is working as my blood sugars have already improved 20% within a month.It is a temporary drastic measure to reduce the fats.

Not all supplements are taken daily , primary source is food .

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 04:59 PM

Ditch the supplements until diet is in line. Supplements are there not as medicine but as filling in gaps in diet.

0
Medium avatar

on December 28, 2013
at 01:08 PM

Ever thought about adopting a high-carb low fat regimen? In your case I'd keep all options open.

And think about drastically reducing the amount of supplements you take. Some of those may very well be harmful, i.e. the iodine and the krill oil.

And you'll probably need to increase your calories, with that low amount of fuel no body tissue can heal properly.

The increasing cholesterol values make me think about a irritated gut, maybe from all the fats, too much meat and lack of carbohydrates. Endotoxin is also involved in insulin resistance.

Overtraining + lack of calories is a surefire way to increase your stress hormones which negatively impact your diabetes and thyroid. I would only do it as a very temporary measure.

32f5749fa6cf7adbeb0b0b031ba82b46

(41747)

on December 28, 2013
at 04:59 PM

Supplements are harmful, give me a break. They're a waste of time, but harmful? Pfft. Irritated gut from fat? Endotoxins? Silliness.

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