6

votes

What paleo research do you want to see done by a grad student?

Answered on August 19, 2014
Created September 22, 2011 at 3:25 PM

I started grad school about a month ago and my original plan was the M.S. -> RD route. Looking into it more and knowing what I know now, there's no way in hell I could ever work unpaid in a hospital telling really sick people to eat things I know are probably terrible for them. I've decided to go the PhD route instead which means I've been thinking a lot about what I want to do my research on. I'm most interested in:

Magnesium, the lack of it in our diets and why we need it

The O3:O6 balance and inflammation + disease

Gluten's effect on brain chemistry and the gut (fairly positive I have Celiac's)

The misguided fear of natural saturated fats and why they're good for us.

What kind of research would the paleo brains here like to feed on? Just trying to narrow down my focus a little bit and this site has been pretty damn helpful with a lot of other questions. My advisor seems pretty cool with me taking the non-conventional route, getting funding for paleo research from our government is a whole different story. Thanks in advance.

Af005ec9a8e028f2b04bf5367b64e0d6

(2797)

on September 07, 2013
at 01:28 AM

you dont want to enjoy food?

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on October 15, 2011
at 04:25 PM

Would be tricky because you'd have to control total amount as well as ratio of omegas.

B9cc28905ec54389c47cde031d709703

on October 15, 2011
at 04:14 PM

Fatty fish dominant diet vs. beef dominant diet.

B9cc28905ec54389c47cde031d709703

on October 15, 2011
at 04:13 PM

Fatty fish dominate diet vs. beef dominate diet.

Cc7381bd787721575ea9198048132adb

(5541)

on September 24, 2011
at 04:36 AM

Really interested in this one. It's a consistent fear in everyone in my Nutrition department and I'm pretty sure the fear isn't justified.

Cc7381bd787721575ea9198048132adb

(5541)

on September 24, 2011
at 04:34 AM

Really interested in this one. Good sat fats are aplenty foods we evolved eating. This is one is a consistent fear in everyone in my Nutrition department and I'm pretty sure the fear isn't justified.

78972387772c994caa78513a83978437

(2290)

on September 23, 2011
at 10:43 PM

Haha noo. I'd at least check online and perhaps contact some of the PIs there. I know for sure someone is working on a low carb/antioxidant sort of project there.

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 04:30 PM

Haha actually just moved to Greensboro from Chapel Hill, worked at UNC for the last 3 years and had no idea Duke was big on low carb dammit!!!

61a27a8b7ec2264b1821923b271eaf54

(3175)

on September 23, 2011
at 04:04 PM

Look at what people are eating now in the name of health, whey protein powders, bars of all sorts, drinks of all sorts...Everyone else is just too overwhelmed and sticks with what they know best: SAD. I'm serious about this request. I'd love to be able to buy a 50lbs sack of human chow! It would have to taste good, be completely paleo in nutrition contents, and come with instructions on how much to eat for my height, weight,body comp or goals.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on September 23, 2011
at 03:01 PM

I think part of the problem is that controlling variables in nutritional science is damn hard. Many of them only half-ass control variables because I think the community tends to give a pass on variable control (in other words, I suspect peer review is lacking.)

89e238284ccb95b439edcff9e123671e

(10299)

on September 23, 2011
at 06:31 AM

Daniel, indeed interesting. See http://www.euro.who.int/__data/assets/pdf_file/0008/136466/e94888.pdf: Burden of disease from environmental noise. Quantification of healthy life years lost in Europe

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 05:18 AM

I looked around and couldn't find much research on this surprisingly. +1 for getting the wheels turning.

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 05:15 AM

The boredom is kind of the whole thought behind the food reward deal, I definitely think it's an interesting idea. It would be interesting to see if people actually "thrive" on such a mundane diet or if it's more of a tool for resetting the body's fat set point for weight loss.

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 05:13 AM

I hear that, as much as I enjoy reading her stuff, I want to avoid being ripped apart by Denise Minger at all costs.

Medium avatar

(4878)

on September 23, 2011
at 03:54 AM

First of all Kibble is filled with horrible processed "not fit for human consumption" foods, so you lost me with the analogy. And, eating the same thing every meal, every day, would result in extreme boredom. I know I couldn't maintain a diet like that for more than a week. Do you have a purpose in mind?

7c9f81d68c78de1a31eab9c91c17b4b8

on September 23, 2011
at 03:50 AM

Yes. Same with my family--It is even a better reason for me to be paleo and stop using toxic products to clean myself or home with. it's so tragic. I don't want my kids to live seeing me not knowing what is going on.

91fe5b7e10068df9f147ee84320e38f7

(614)

on September 23, 2011
at 12:50 AM

Interesting, though personally, ugh. Do you really think you could thrive on that? Question for food reward knowledgeable, perhaps.

6120c989fd5b69f42a0834b69b87955b

(24553)

on September 22, 2011
at 11:08 PM

I watched a comedian the other night, who said "We lost my mom in 2001, and she finally passed away in 2009. For those of you who have been through it you know what I mean." The laughter from the audience seemed both nervous and cathartic. Having lost 3 grandparents to Alzheimer's long before the end of their lives, I was laughing and crying at the same time.

6120c989fd5b69f42a0834b69b87955b

(24553)

on September 22, 2011
at 11:07 PM

I watched a comedian the other night, who said "We lost my mom in 2001, and she finally passed away in 2009. For those of you who have been through it you no what I mean." The laughter from the audience seemed both nervous and cathartic. Having lost 3 grandparents to Alzheimer's long before the end of their lives, I was laughing and crying at the same time.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 09:50 PM

Alzheimer's results in a heart-breaking loss of friends/relatives before they are dead. My mother had dementia and then Alzheimer's and I would love to protect myself from going down the same road.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 09:24 PM

My great aunt had Alzheimer's before she died and it was pretty terrible to see her go through something that awful, the gut/brain connection is definitely high on my list.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 05:53 PM

I'm also very interested in the same topic but even my advisor thought I would have an extremely hard time getting funding for something like that. I'm pretty sure I had some form of it when eating SAD so it hits close to home. Going to explore this one some more for sure.

91fe5b7e10068df9f147ee84320e38f7

(614)

on September 22, 2011
at 05:20 PM

+ 1. Unfortunately, though, it probably won't garner gov't funding, as Big Pharma would lose out on a huge drug market.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 04:09 PM

I'll have to do some searching on this also, would be very interesting either way.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 04:08 PM

As a Crossfitter I like where you're going with this one, especially the similar body types part. +1

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12 Answers

7
7c9f81d68c78de1a31eab9c91c17b4b8

on September 22, 2011
at 07:07 PM

Alzeimer's and diet--Type 3 diabetes or the gut/brain connection or any sub-set therein.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 09:24 PM

My great aunt had Alzheimer's before she died and it was pretty terrible to see her go through something that awful, the gut/brain connection is definitely high on my list.

7c9f81d68c78de1a31eab9c91c17b4b8

on September 23, 2011
at 03:50 AM

Yes. Same with my family--It is even a better reason for me to be paleo and stop using toxic products to clean myself or home with. it's so tragic. I don't want my kids to live seeing me not knowing what is going on.

6120c989fd5b69f42a0834b69b87955b

(24553)

on September 22, 2011
at 11:08 PM

I watched a comedian the other night, who said "We lost my mom in 2001, and she finally passed away in 2009. For those of you who have been through it you know what I mean." The laughter from the audience seemed both nervous and cathartic. Having lost 3 grandparents to Alzheimer's long before the end of their lives, I was laughing and crying at the same time.

77877f762c40637911396daa19b53094

(78467)

on September 22, 2011
at 09:50 PM

Alzheimer's results in a heart-breaking loss of friends/relatives before they are dead. My mother had dementia and then Alzheimer's and I would love to protect myself from going down the same road.

6120c989fd5b69f42a0834b69b87955b

(24553)

on September 22, 2011
at 11:07 PM

I watched a comedian the other night, who said "We lost my mom in 2001, and she finally passed away in 2009. For those of you who have been through it you no what I mean." The laughter from the audience seemed both nervous and cathartic. Having lost 3 grandparents to Alzheimer's long before the end of their lives, I was laughing and crying at the same time.

6
32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on September 23, 2011
at 02:52 AM

Just be methodical and control variables, please please please! Nutritional science is so god-awful compared to other sciences, it's embarrassing.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on September 23, 2011
at 03:01 PM

I think part of the problem is that controlling variables in nutritional science is damn hard. Many of them only half-ass control variables because I think the community tends to give a pass on variable control (in other words, I suspect peer review is lacking.)

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 05:13 AM

I hear that, as much as I enjoy reading her stuff, I want to avoid being ripped apart by Denise Minger at all costs.

6
Dc6407193ba441d1438f6f0c06af872b

on September 22, 2011
at 05:05 PM

ADHD and diet. Considering how many kids have it, how quick the results might be if diet is important, and how skeptical the mental health community is that diet matters, it could be a rich area for discovery and impact, both for the kids and indirectly for paleo itself. Emily Deans blogged on some minimal research being done, http://www.psychologytoday.com/blog/evolutionary-psychiatry/201106/how-does-diet-affect-symptoms-adhd.

91fe5b7e10068df9f147ee84320e38f7

(614)

on September 22, 2011
at 05:20 PM

+ 1. Unfortunately, though, it probably won't garner gov't funding, as Big Pharma would lose out on a huge drug market.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 05:53 PM

I'm also very interested in the same topic but even my advisor thought I would have an extremely hard time getting funding for something like that. I'm pretty sure I had some form of it when eating SAD so it hits close to home. Going to explore this one some more for sure.

6
6b365c14c646462210f3ef6b6fecace1

(1784)

on September 22, 2011
at 03:33 PM

Are certain populations better genetically predisposed to tolerate a diet of specific macronutrient ratio?

ex) do certain populations fare better on low/high carb, protien, and/or fat

I actually don't know if this has been studied before. I guess I should get off my lazy bum and do a search...

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 04:09 PM

I'll have to do some searching on this also, would be very interesting either way.

4
Af005ec9a8e028f2b04bf5367b64e0d6

on September 22, 2011
at 03:28 PM

A controlled, >6 month long experiment with a paleo or perfect-health type diet (no vegetable oils, gluten, peanuts/soy, little sugar) on high-level athletes, compared to a traditionally prescribed low-fat diet and/or a Mediterranean diet. Measure health markers and performance. Maybe lightweight rowers or something to get similar body types.

Cc7381bd787721575ea9198048132adb

(5541)

on September 22, 2011
at 04:08 PM

As a Crossfitter I like where you're going with this one, especially the similar body types part. +1

3
79fc447191de75e7c178951594a43f13

(448)

on September 22, 2011
at 10:53 PM

Blacks and vitamin D. You could probably get funding really easily, yet open yourself up to the thought police.

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 05:18 AM

I looked around and couldn't find much research on this surprisingly. +1 for getting the wheels turning.

2
Da3d4a6835c0f5256b2ef829b3ba3393

on October 15, 2011
at 05:40 PM

Long term analysis of lipid numbers and those who avoid the top dangers of the SAD.

(I personally have this notion that many or most of the things we are warned about, things like high cholesterol, aren't so dangerous, and particularly aren't so dangerous for those who follow the basic paleo tenets.)

2
B9cc28905ec54389c47cde031d709703

on October 15, 2011
at 04:11 PM

The effect of polyunsaturated fats on the thyroid and metabolic rate.

B9cc28905ec54389c47cde031d709703

on October 15, 2011
at 04:14 PM

Fatty fish dominant diet vs. beef dominant diet.

B9cc28905ec54389c47cde031d709703

on October 15, 2011
at 04:13 PM

Fatty fish dominate diet vs. beef dominate diet.

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on October 15, 2011
at 04:25 PM

Would be tricky because you'd have to control total amount as well as ratio of omegas.

2
3432683fc74c2d2a40efe1e8f16ac1f6

(1130)

on September 23, 2011
at 10:14 PM

I like your last proposal about fear of fats. Vote fot that.

Cc7381bd787721575ea9198048132adb

(5541)

on September 24, 2011
at 04:34 AM

Really interested in this one. Good sat fats are aplenty foods we evolved eating. This is one is a consistent fear in everyone in my Nutrition department and I'm pretty sure the fear isn't justified.

Cc7381bd787721575ea9198048132adb

(5541)

on September 24, 2011
at 04:36 AM

Really interested in this one. It's a consistent fear in everyone in my Nutrition department and I'm pretty sure the fear isn't justified.

2
78972387772c994caa78513a83978437

on September 23, 2011
at 03:46 PM

You're in NC? There are a lot of labs at Duke working on low-carb type research. Check out the people in the bio/biochem departments. I'm sure you will be able to get some ideas there.

78972387772c994caa78513a83978437

(2290)

on September 23, 2011
at 10:43 PM

Haha noo. I'd at least check online and perhaps contact some of the PIs there. I know for sure someone is working on a low carb/antioxidant sort of project there.

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 04:30 PM

Haha actually just moved to Greensboro from Chapel Hill, worked at UNC for the last 3 years and had no idea Duke was big on low carb dammit!!!

2
25b139cc1954456d9ea469e40f984cd3

on September 23, 2011
at 06:22 AM

Effect of noise pollution vs. relative quiet on stress levels, mood, etc.

89e238284ccb95b439edcff9e123671e

(10299)

on September 23, 2011
at 06:31 AM

Daniel, indeed interesting. See http://www.euro.who.int/__data/assets/pdf_file/0008/136466/e94888.pdf: Burden of disease from environmental noise. Quantification of healthy life years lost in Europe

2
61a27a8b7ec2264b1821923b271eaf54

(3175)

on September 22, 2011
at 11:50 PM

I would like to see someone develop a Purina-type "People Chow". A tasty food that had everything in it a person could thrive on. No more need for supplements, grass-fed beef, offal--just a crunchy pellet I could eat a certain amount of and optimize myself. You would have to be mindful of reward theories, nutrient content, and palatability. You could even develop different types for different goals, weight-loss chow, weight-gain chow, old-age chow, baby-chow.

This food would have no neurotoxins (MSG/aspartate), the proper 03:06 ratio, and leave you satiated without triggering reward tracts in the brain.

Cc7381bd787721575ea9198048132adb

(5541)

on September 23, 2011
at 05:15 AM

The boredom is kind of the whole thought behind the food reward deal, I definitely think it's an interesting idea. It would be interesting to see if people actually "thrive" on such a mundane diet or if it's more of a tool for resetting the body's fat set point for weight loss.

Af005ec9a8e028f2b04bf5367b64e0d6

(2797)

on September 07, 2013
at 01:28 AM

you dont want to enjoy food?

Medium avatar

(4878)

on September 23, 2011
at 03:54 AM

First of all Kibble is filled with horrible processed "not fit for human consumption" foods, so you lost me with the analogy. And, eating the same thing every meal, every day, would result in extreme boredom. I know I couldn't maintain a diet like that for more than a week. Do you have a purpose in mind?

91fe5b7e10068df9f147ee84320e38f7

(614)

on September 23, 2011
at 12:50 AM

Interesting, though personally, ugh. Do you really think you could thrive on that? Question for food reward knowledgeable, perhaps.

61a27a8b7ec2264b1821923b271eaf54

(3175)

on September 23, 2011
at 04:04 PM

Look at what people are eating now in the name of health, whey protein powders, bars of all sorts, drinks of all sorts...Everyone else is just too overwhelmed and sticks with what they know best: SAD. I'm serious about this request. I'd love to be able to buy a 50lbs sack of human chow! It would have to taste good, be completely paleo in nutrition contents, and come with instructions on how much to eat for my height, weight,body comp or goals.

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