4

votes

Does a paleo lifestyle compress morbidity and decelerate mortality more than gompertz law predicts?

Answered on August 19, 2014
Created April 15, 2011 at 11:26 PM

My clinical belief and my academic belief are that a paleo lifestyle especially key dietary pillars are critical to compressing disease and expanding health as one ages. This is a new area of study because the paleo lifestyle is not commonly implemented by supercentarians so we may have to wait sixty plus years too see it's effects. It is critical to follow paleo community habits now to draw conclusions about the habits developed and types of foods eaten. This is an area that has me intensely interested in going forward........would love to hear some of your thoughts on this 30000 ft view of the paleo lifestyle and what the future may reveal.

Gompertz Law: risk of death increases exponentially with age.

2507b557331c8a674bc81197531e609a

(4994)

on April 16, 2011
at 11:53 PM

Well, when you put it like that ;D you make a compelling argument for sure but I still believe living in the here and now goes a long way, I also thin there's a lot to be be said for what you are advocating too and I shall certainly be reading your blog when it comes :)

06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 16, 2011
at 09:05 PM

I think most of are ready for the 15 factors.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 08:12 PM

Meat fish HIIT and avoiding aerobics are some

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 08:11 PM

Plenty....paleo lifestyle incorporates many......without screwing some of my future blog topics......it's is easier than you think

2f54dbe892ec89b12d1db686568e885a

(919)

on April 16, 2011
at 06:59 PM

apart from gene therapy or drugs, is there anything dietary which you feel may now achieve an increase in telomere length Dr. K?

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:17 PM

It's easier than you think......the ultimate metric is now clear.."...it's telomere length. Anything that increases it will be paleo soon......just watch

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:16 PM

And why my blog will focus in topics Germaine to this area.......

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:15 PM

My focus is on the newest mortality trend since the 1950's......the surprising effect of declining mortality rates as one ages. The key to this derectangular finding is getting to an elder age with as much health and vitality and stem cells as one can muster.....because it's clear we have a lot of potential to extend life at the back end if we do things correctly for the first seventy years.....this is why de vany and lalane and calment interest me greatly

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:10 PM

Carly......I disagree with the premise. The more I focus on morbity and mortality the more I enjoy life. The more I focus on love, sex, age management, Kama sutra, paleo living, hormonal optimization, and stress reduction the more intense my love life and wife happiness is. It's all tied up together......the more I know the better I become. I discussed your post with my wife at lunch and she also disagreed with you. I respect your opinion and glad you shared it because it got me thinking more deeply why I do what ido.....and it's to live better than I used too yesterday.

2507b557331c8a674bc81197531e609a

(4994)

on April 16, 2011
at 05:03 PM

I agree with you completely on that statement Doctor K, I'm merely expressing the view that too much focus on mortality takes the focus away from life itself. Make the right choices with the info we have and enjoy living! We're not going to get to the end of our hopefully healthy lives and think "I wish I'd spent more time focussing on my mortality" We are more likely to get to the end of our lives wishing we'd lived a little more in the moment and enjoyed it.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 04:22 PM

Stabby for me it's critical. I spend a lot of free time compressing disease and mortality in how I do things in the OR and in my practice. Metabolic pathways and longevity pathways are critical to me. It's why making paleo 2.0 is just not for me. The details are where the pot of gold lies

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 04:20 PM

Stabby for me it's critical. I spe

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 04:19 PM

There will be eventually. That is why the paleo community needs to track their health metrics going forward

06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 16, 2011
at 04:18 PM

Yeah right. Try to get a life insurance company not to rate up for a fit person paleo total cholesterol of 300.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 04:18 PM

I disagree obviously. The more we know the better we can become

2f54dbe892ec89b12d1db686568e885a

(919)

on April 16, 2011
at 04:11 PM

should be a reduction in premiums for paleo followers then

06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 16, 2011
at 02:55 PM

But life insurance companies tell us by the premiums they charge that chances of death by accident is less than death by all causes.

Be1dbd31e4a3fccd4394494aa5db256d

(17969)

on April 16, 2011
at 05:10 AM

Compression of morbidity looks important. I'm confident that I know at least a bit about what will minimize aging but being a sickie from 80-100 might not be so fun. Good question! beyond my knowledge.

21fd060d0796fdb8a4a990441e08eae7

(24543)

on April 15, 2011
at 11:34 PM

Edited to include Gompertz Law.

  • Ed71ab1c75c6a9bd217a599db0a3e117

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6 Answers

4
06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 15, 2011
at 11:40 PM

I know one gentleman that lives in the community I do who is 99 years old and plays senior softball twice a week and bowls twice a week. One day at the ballfield, I asked him what is the key to his longevity and he told me, limit sugar, limit bread, be happy and get lots of sunshine every day and get out of the house and do something. He has been eating this way for 40 years and has been playing ball in the sunshine 19 years. Maybe the first paleo without know it.

I started paleo 3.5 years ago at age 63 and have never felt better, but can't remember my teens and 20s since back then I was going to live forever. I do know I abused my body mercilessly with 40 oz of Coke from 7-11 for years. But so far this paleo thing has turned into a lifestyle. It is amazing what happens when one's mortality slaps one up aside the head and says if you continue down this road, the end is near. Not for me now. I hope to break the record. The oldest living person just died yesterday in Montana at the age of 110.

2
2507b557331c8a674bc81197531e609a

(4994)

on April 16, 2011
at 10:02 AM

Personally I think focussing too much on morbidity and mortality is un-healthy and counter productive as it creates anxieties. Just enjoy being healthy now, there is no way of measuring now whether we are increasing our life span or not so we shouldn't worry too much about it. Just make good choices with what info we know and chill down and enjoy life.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 04:18 PM

I disagree obviously. The more we know the better we can become

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:10 PM

Carly......I disagree with the premise. The more I focus on morbity and mortality the more I enjoy life. The more I focus on love, sex, age management, Kama sutra, paleo living, hormonal optimization, and stress reduction the more intense my love life and wife happiness is. It's all tied up together......the more I know the better I become. I discussed your post with my wife at lunch and she also disagreed with you. I respect your opinion and glad you shared it because it got me thinking more deeply why I do what ido.....and it's to live better than I used too yesterday.

2507b557331c8a674bc81197531e609a

(4994)

on April 16, 2011
at 05:03 PM

I agree with you completely on that statement Doctor K, I'm merely expressing the view that too much focus on mortality takes the focus away from life itself. Make the right choices with the info we have and enjoy living! We're not going to get to the end of our hopefully healthy lives and think "I wish I'd spent more time focussing on my mortality" We are more likely to get to the end of our lives wishing we'd lived a little more in the moment and enjoyed it.

2507b557331c8a674bc81197531e609a

(4994)

on April 16, 2011
at 11:53 PM

Well, when you put it like that ;D you make a compelling argument for sure but I still believe living in the here and now goes a long way, I also thin there's a lot to be be said for what you are advocating too and I shall certainly be reading your blog when it comes :)

2
Medium avatar

(5136)

on April 15, 2011
at 11:52 PM

I can't speak to the Gompertz law per se, as I imagine a large part of that equation has to do with things like "the more often you cross the street, the more likely it is a car will hit you" and so forth. When it comes to Paleo though, I wonder how much we will really be able to tell in this generation. Aren't there so many potential factors like sub optimal health of one's parents before your own birth, a childhood diet that was sub-optimal and particularly any viruses or illnesses that may have done their damage before a person found the primal diet? That said, I do believe a paleo diet goes a long way to rectifying these situations, so maybe if most of us live to 108 that will be all the more proof of its power.

Otherwise we might have to wait til our Paleo children are 108.

1
Cc2a43461ec5b2b7ba5d55215ea0f068

on April 16, 2011
at 05:43 PM

I wonder how you could design such a study. The population, even on this board, that is following any semblance of paleo is so scattered with so many different versions, that that would have to be part of the mathematical function. What would the control variable be? What sort of design for tracking would you put in place? In the larger scheme of things, IMO, a very worth-while subject to study with a really good logistical road-map.

I do think that the impact of this diet and way of living can be at least tracked with simple metrics regarding common disease incidence in Paleo vs. SAD, since an improved immune system is one of the benefits. We talk most frequently here about the big five (cancer, diabetes, hyper-tension, heart disease and high cholesterol), but what about the common cold and flu? For years, I had maybe one cold a year and in the last two years, I guess, I caught everything I came in contact with until the paleo benefits kicked in in January. I've been incredibly well since. I think with a good control group, a study of this sort is totally doable.

That being said, what is your threshold for "longevity"? I have a 99 year old aunt who smoked, ate SAD and bowled for exercise. I have a friend who's father is 105 and just had a second hip replacement. His diet most likely leans vegetarian. In both cases, getting to 85 in the family is perfectly normal. I suppose I'm asking regarding the initial hypothesis, is genetics going to be considered, because we all have family that abuse the heck out of their bodies and somehow live to tell the tale, albeit on anti-hyperintensives, chemo, insulin, etc.

I hope you do start such a study that tracks 2-3 generations on paleo or at least grain, legume and simple sugar (for the most part) free. I think the results would be fascinating.

2f54dbe892ec89b12d1db686568e885a

(919)

on April 16, 2011
at 06:59 PM

apart from gene therapy or drugs, is there anything dietary which you feel may now achieve an increase in telomere length Dr. K?

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 08:12 PM

Meat fish HIIT and avoiding aerobics are some

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 08:11 PM

Plenty....paleo lifestyle incorporates many......without screwing some of my future blog topics......it's is easier than you think

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:17 PM

It's easier than you think......the ultimate metric is now clear.."...it's telomere length. Anything that increases it will be paleo soon......just watch

1
C33e8c236e72d67c4b6c028401d23cce

(1884)

on April 16, 2011
at 12:41 PM

A Gompertz curve is a mathematical function determined by several variables and one constant. The actual rate of growth, the "steepness" of the curve (of mortality, in this case) would be determined in part by any environmental factor that affects lifespan. Since there are too many of those factors to really count, and those factors are nearly impossibly to quantify this makes it a pretty useless tool for predicting real-world mortality rates in actual numbers.

The function itself, though, is consistent with the tautology that, the less dangerous your life is, the less chance you have of dying.

06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 16, 2011
at 02:55 PM

But life insurance companies tell us by the premiums they charge that chances of death by accident is less than death by all causes.

06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 16, 2011
at 04:18 PM

Yeah right. Try to get a life insurance company not to rate up for a fit person paleo total cholesterol of 300.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 04:19 PM

There will be eventually. That is why the paleo community needs to track their health metrics going forward

2f54dbe892ec89b12d1db686568e885a

(919)

on April 16, 2011
at 04:11 PM

should be a reduction in premiums for paleo followers then

1
2f54dbe892ec89b12d1db686568e885a

(919)

on April 16, 2011
at 11:53 AM

If you had nothing better to do than look at the life expectancy tables used by actuaries, rather than supporting Gompertz' Law, they show the reverse. In fact, statistically, as people move towards the age of 60 their actual life expectancy increases quite dramatically.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:16 PM

And why my blog will focus in topics Germaine to this area.......

06d21b99c58283ce575e36c4ecd4a458

(9948)

on April 16, 2011
at 09:05 PM

I think most of are ready for the 15 factors.

Ed71ab1c75c6a9bd217a599db0a3e117

(25482)

on April 16, 2011
at 06:15 PM

My focus is on the newest mortality trend since the 1950's......the surprising effect of declining mortality rates as one ages. The key to this derectangular finding is getting to an elder age with as much health and vitality and stem cells as one can muster.....because it's clear we have a lot of potential to extend life at the back end if we do things correctly for the first seventy years.....this is why de vany and lalane and calment interest me greatly

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