Should people not responding to weightloss on paleo consider testing for antibodies to obesigenic viruses?

Answered on August 19, 2014
Created October 08, 2011 at 5:55 AM

I'm not sure what someone would do with that info once they had it...antiviral treatment?...focus on immune support? But it might help with some of the hitting one's head against the wall frustration from doing "everything right" but not seeming to make any headway.

"This review discusses the 5 animal viruses and 3 human viruses that have been shown to cause obesity??? The first 4 viruses attack the central nervous system to produce obesity. SMAM-1, an avian adenovirus from India, acts directly on adipocytes and is the only animal virus that is associated with human obesity. The 3 human adenoviruses, adenovirus (Ad) 36, Ad-37, and Ad-5, that are associated with obesity also affect adipocytes directly. These viruses stimulate enzymes and transcription factors that cause accumulation of triglycerides and differentiation of preadipocytes into mature adipocytes. Ad-5 and Ad-37 have been shown to cause obesity in animals. Ad-36 has been studied the most and is the only human adenovirus to date that has been linked with human obesity. Ad-36 causes obesity in chickens, mice, rats, and monkeys and was present in 30% of obese humans and 11% of nonobese humans. In twins discordant for infection with Ad-36, the infected twins were heavier and fatter than their cotwins. The growing body of evidence demonstrating that viruses produce human obesity supports the concept that at least some of the worldwide epidemic of obesity in the past 25 years is due to viral infections." 229)




on December 20, 2012
at 10:40 PM

You can ask to be tested for antibodies to various viruses. I'm not sure what all you'd want to ask for, I bet your doc could point you in the right direction. I've only done the tests for certain bacterial infections at the urging of my midwives, I can't remember what they cost, but I don't remember being shocked by my remainder after it went through insurance.



on December 20, 2012
at 10:15 PM

How do I get this test done, and how much does it cost?


on December 20, 2012
at 06:26 AM

Or maybe you don't work out?

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3 Answers


on January 03, 2013
at 01:22 PM

In answer to the question header (though not the details) there's the simple fact that Paleo is not in itself a weight loss diet, period.


on January 03, 2013
at 01:54 PM

Do you currently keep track of calories? Do you know what your BMR is? Have tried varying your macornutrient ratios? Do you exercise? Have you incorporated both cardio AND weight training? Have you tried fasted cardio? Have you tried "6 small meals a day"? If that didn't work, have you tried intermittent fasting? What's your current diet like? What other diet strategies have you tried? Are you in truth 100% faithful to your meal plan?

In short, try harder.


on November 22, 2012
at 04:28 AM

I would take a closer look at your carb content and not just if you're paelo enough. There's a difference between paleo and low carb (too much sweet potato, fruit, dark chocolate maybe?). Also, hard to help point into the right direction without stats (sex, height, weight, etc).

Typically, when it comes to weight loss and paleo lifestyle go with Occam's razor on this one. It's probably a lack of caloric defecit issue as compared to an exotic rare virus.


on December 20, 2012
at 06:26 AM

Or maybe you don't work out?

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