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Fat Cell Number vs. Size

Answered on September 26, 2013
Created September 25, 2013 at 9:37 AM

For those of us who grew up obese, but no longer are, would there be any benefits for fat cell removal procedures such as liposuction?

I grew up obese so although I'm currently healthy and athletic at 8% body fat, I figure I probably do have a higher number of fat cells than most people.

So I was thinking... Are there any benefits to remove some of that fat? One question that I've had for a while is about aromatization of testosterone into estrogen, for example. I know this is done by fat cells, but is the rate of this aromatization process determined by fat cell NUMBER or SIZE?

Thanks in advance.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on September 26, 2013
at 04:34 AM

@mills i know my 'answer' does not directly address your questions. but it relates to your liposuction query, If it can be established that the number of fat cells can be reduced over a period of years under the right circumstances.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on September 26, 2013
at 02:01 AM

has any one seen any new/recent studies on life & death of fat (adipocytes, adipose) cells...

the theory of fat cell numbers fixed for life is no longer current, i believe there are studies out there showing both adipose hypertrophy and adipose hyperplasia, under the right circumstances.

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3 Answers

0
2271d683e399f1c43931291d58e927b3

on September 26, 2013
at 11:48 AM

Studies have shown that fat cell count is highly heritable. It's probably due to your bad genes and there is little one can do about it.

0
86455cd6a3772691f6524ef0db72233d

on September 26, 2013
at 07:21 AM

Sounds promising. I did some Googling and yes, it seems that fat cells do die and get replaced, the mechanism that controls the rate of this turnover is currently unknown. The question here isn't cosmetic. I already know that we can all be thin and stay thin with good lifestyle choices. What I'm most curious about is whether a higher number of fat cells contribute to anything metabolically. Does a thin, high-fat-cell-count person whose fat cells are small get more aromatization of his testosterone than a fat person with low-fat-cell-count for example? Since these cells each have their organelles which do the work, I'd think more worker bees would have bigger effects then less but bigger ones. After all, it's not the active organelles that expand or shrink, it's the lipid portion.

0
543a65b3004bf5a51974fbdd60d666bb

(4493)

on September 26, 2013
at 02:02 AM

has any one seen any new/recent studies on life & death of fat (adipocytes, adipose) cells.

the theory of fat cell numbers fixed for life is no longer current, i believe there are studies out there showing both adipose hypertrophy and adipose hyperplasia, under the right circumstances.

fat cells have a life cycle (like most cells) and eventually die, though studies show they are replaced with an equal amount of new fat cells. I have seen numbers for this fat cell turnover of between 8 & 10% per year. & this study puts it as high as "between 1–5% of adipocytes are replaced each day".

just wondering if views have changed a bit & acknowledge that the number of fat cells may be able to be reduced under the right circumstances.

a good study would be one where fat cells were counted (if that's possible) in people after they had lost a lot of fat, & then counted again 5 & 10 years later in the people who's body fat percent had remained constant (or trended down) throughout those years.

543a65b3004bf5a51974fbdd60d666bb

(4493)

on September 26, 2013
at 04:34 AM

@mills i know my 'answer' does not directly address your questions. but it relates to your liposuction query, If it can be established that the number of fat cells can be reduced over a period of years under the right circumstances.

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