1

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i am not absorbing D3...

Answered on August 19, 2014
Created November 18, 2012 at 2:11 PM

i have been extremely low in vitamin D3 for years, the first time i was tested it was 6 and the last time 24. i take dilantin for epilepsy (200 mgs per day) and that prevents absorption. i have taken huge doses of D3 up to 50,000 units a day and now i am on injections and nothing changes. any ideas???

8d6390b3b8991a9cb653a3d13c1cbf6a

(543)

on November 18, 2012
at 06:11 PM

Interesting thought. My D3 and K2 intakes have been relatively constant, but I added liver a few months ago so A intake is much much higher. I'll have D3 tested in the next few months, and am curious.

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5 Answers

3
8d6390b3b8991a9cb653a3d13c1cbf6a

(543)

on November 18, 2012
at 05:24 PM

Are you sure the 50,000iu dose was of D3, and not D2? The prescription version of vitamin D is often given in 50,000 iu pills, but is D2 rather than D3, so seems to be less effective for many folks. (The prescription version was approved before D3 was discovered, and the cost to get the D3 form approved is prohibitive given you can buy it over the counter)

I was taking about 2500iu of D3 and had a level of 18. Taking the prescription pills brought it up to 22. Buying 5000iu over the counter D3 gelcaps solved the problem nicely.

If you really have been taking 50,000iu of D3, then the only question I'd have is for how long you've been doing it. If it's been a few months, that sounds like something could be seriously wrong or it's a reaction to the dilantin, which interferes with vitamin D. In either case, I suggest talking with your doctor. Perhaps he can suggest a different anticonvulsant? Or, you could chat with your doc about trying staying in nutritional ketosis and seeing if that improves your epilepsy. Perhaps that would enable you to reduce the dose of dilantin?

1
A2c38be4c54c91a15071f82f14cac0b3

(12682)

on November 18, 2012
at 07:03 PM

If you're getting 25-hydroxy vitamin D tested, it may be worthwhile trying to get your 1,25-dihydroxy vitamin D tested. A cursory search of studies of dilantin/phenytoin shows that it can sometimes (but not always) produce lower levels of the biomarker for vitamin D (the 25-hydroxy form) but not the active form (the 1,25-dihydroxy form).

So you may end with adequate levels of the active, important form, but lower levels of the form you're getting tested. This is probably worth looking in to.

http://www.ncbi.nlm.nih.gov/pubmed/220903

http://www.ncbi.nlm.nih.gov/pubmed/6981091

1
Cb9a270955e2c277a02c4a4b5dad10b5

(10989)

on November 18, 2012
at 06:00 PM

Have you looked into the synergistic effects of vitamin d3 with k2 and vitamin a? I know that Weston Price really strongly advocated the combination of Vitamins A,D and K2. I've heard that the interrelationship between these vitamins isn't fully understood yet and I'd be curios to see if taking these supplements together results in elevated serum d levels. It's just a hunch though.

8d6390b3b8991a9cb653a3d13c1cbf6a

(543)

on November 18, 2012
at 06:11 PM

Interesting thought. My D3 and K2 intakes have been relatively constant, but I added liver a few months ago so A intake is much much higher. I'll have D3 tested in the next few months, and am curious.

0
366c23d69eadce094a2b22299c58a424

(2988)

on November 19, 2012
at 12:46 AM

Not really an answer, just wanted to add that if you check out mortality charts on D3, there is a rather big difference between 6 and 24.

0
5e5ff249c9161b8cd96d7eff6043bc3a

(4713)

on November 18, 2012
at 08:57 PM

I second the A and K2 notions, and would add that magnesium is also a cofactor, so you want to make sure your intake is sufficient.

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