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What's the deal with nicotine (NOT TOBACCO) ? Is it bad for you?

Answered on February 21, 2015
Created February 27, 2014 at 10:31 PM

I am not talking about cigarettes. There is nobody on this planet that doubts cigarettes are bad for you.

I am talking about pure nicotine delivered either through e-cigs, patches or gum. Does nicotine possess any negative qualities besides being addictive? I'd read conflicting reports that nicotine may actually be beneficial and may encourage proper blood vessel function as well as decreasing Alzheimer's risk.

D371623b5671d11fa678b201ff23442b

on March 01, 2014
at 01:54 AM

The dose makes the poison. Good luck getting 60mg of nicotine into your bloodstream without injecting it.

96440612cf0fcf366bf5ad8f776fca84

(19473)

on February 28, 2014
at 02:57 PM

It's also been used to murder people in the 1800s, so yeah, avoid high doses:

http://www.wired.com/wiredscience/2012/05/nicotine-and-the-chemistry-of-murder/

089dd41b18fbb95ebb5347cded708d98

(5635)

on February 28, 2014
at 03:28 AM

it helps with ulcerative colitis.

D371623b5671d11fa678b201ff23442b

on February 28, 2014
at 03:23 AM

If you were never a smoker, why are you on the patch?

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7 Answers

0
A83576a9f44259787cb153bc17436580

on February 21, 2015
at 04:25 AM

There's nothing wrong with smoking organic tobacco as long as it's not excessive.  Some of the world's longest lived people smoked cigarettes.  Cigarettes prevent parkinson's, alzheimer's, and optimize hormone production.  It's the nasty additives that are in conventional cigarettes that wreak havoc and cause cancer and other disease.  

I do not smoke cigarettes becaues I do not want to get wrinkles or a raspy voice, but I will have one on occassion.  

 

Most people believe marijuana to be harmless and it probably is.

But if that marijuana included battery acid, flame retardants, and other crap would they say the same thing?

0
Cbda678b2a6bf0537d8c4ea0ce8aa9ad

(4319)

on February 28, 2014
at 10:15 PM

Nicotine is one of the most toxic and addicting of all drugs. 60mg is a lethal does for a 150 pound human. Arsenic requires 200mg in the same scenario.

D371623b5671d11fa678b201ff23442b

on March 01, 2014
at 01:54 AM

The dose makes the poison. Good luck getting 60mg of nicotine into your bloodstream without injecting it.

0
96440612cf0fcf366bf5ad8f776fca84

(19473)

on February 28, 2014
at 02:58 PM

This isn't so much an answer as a note. I've seen somewhere, wish I could remember where, that nicotine is very similar to niacin and that people who are addicted to it are self medicating with niacin (in addition to the dopamine effects, of course).

I did find this just now, but isn't the original source I saw:

http://www.sott.net/article/270514-Nicotine-vs-nicotinic-acid-niacin

0
F92f0b6a3fe3d45a489e020076904f2f

on February 28, 2014
at 03:32 AM

I dunno, I had an e-cigarette last fall, used it all the time, but I lost it last month and I never went through withdrawl or anything. I never smoked cigarettes, I just liked e-cigs.

I will say that the concentration of nicotine does make a huge difference... if you vape with the 6ml, that's fine, it may cause lightheadedness if you overuse. ANything more and I'm pretty sure it's a health hazard... it caused me to vomit and have a bloody nose................. :-O

96440612cf0fcf366bf5ad8f776fca84

(19473)

on February 28, 2014
at 02:57 PM

It's also been used to murder people in the 1800s, so yeah, avoid high doses:

http://www.wired.com/wiredscience/2012/05/nicotine-and-the-chemistry-of-murder/

0
089dd41b18fbb95ebb5347cded708d98

(5635)

on February 28, 2014
at 01:04 AM

i have heard that nicotine is a problem to use during pregnancy and breastfeeding, but i think if it keeps the mother healthy, then it's not bad. if i got pregnant, i'd still plan on using patches daily. i've been using 21 mg a day for a few weeks now and feel so much better. i have never smoked so i had to work up to 21 mg and started at 4 mg a day.

D371623b5671d11fa678b201ff23442b

on February 28, 2014
at 03:23 AM

If you were never a smoker, why are you on the patch?

0
8b9c2dcd3dfc929a0428d3d6dac4918e

(70)

on February 27, 2014
at 11:47 PM

Nicotine? Well its obviously addictive, although not as addictive as combustion tobacco. And it raises your heart rate. Its probably _roughly_ comparable in that regard to caffiene. In e-cigs there is the PG, and that has some metabolites that some are allergic too, but its also in a lot of processed foods and medicines in larger amounts. It probably not ideal, but a lot safer than carcinogens and oxidation ala smoking. It does seems to lower alzheimers risk, and parkinsons risk probably via stimulation of the dopamine response. The mao inhibitors in tobacco also lower depression, and many find for some reason that tobacco can lower the symptoms of chrones (sp) disease. Nicotine is also good for focus and memory according to studies. There is also "swedish snus" but that is slightly more health risk than e-cigs, and they are probably way too strong for non-smokers.

0
Medium avatar

on February 27, 2014
at 11:17 PM

I heard Dave Asprey mention it on a podcast recently, I found a transcript of an earlier podcast with a blurb about it

"In terms of supplementing with nicotine gum for focus, I think it‟s a bad idea. It‟s not that I have a problem with nicotine; it‟s that I have a problem with the crap they put in there to make it taste good. Every nicotine gum I‟ve found has Nutrasweet or other additives in it that are particularly not healthy for you. Aspartame, despite what you heard on the show today, I think that there is plenty of evidence that there is no benefit to taking aspartame and I also believe that there are some substantial dangers to doing it. Why you would choose to supplement with nicotine for focus while adding something that can have a cognitive effect that doesn‟t help with focus – not a good call.

What I use for mental focus, maybe once or twice a month, is the patch. I go out and buy the nicotine patch and I also think that e-cigarettes would be healthier for you than chewing the gum. The e-cigs, if you by the right flavor, have only have propylene glycol and nicotine in them. I don‟t think propylene glycol burned is probably that good for you but it‟s probably better for you than the additives to the gums. I also don‟t think you should do this every day and get addicted but providing some extra niacin and some extra nicotine for the nicotinic receptors in your brain does help with creativity. That‟s why you see so many famous artists and writers sit back, relax, and take a puff. They are doing something to hack their brains. They are self medicating and I don‟t see anything wrong with doing this. Nicotine without all the crap that‟s in cigarette smoke doesn‟t appear to be that bad for you. There is some conflicting evidence there but frankly I‟d rather have nicotine than aspartame any day of the week."

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