For MTHFR, are the B12, folate found in liver or egg yolks already methylated? And does cooking damage them? Or are supplements needed? I started on methylfolate in the AM and methyl B12 at night, and have noticed some improvements in sleep... (more)
I have read several places online that if you do not tolerate sulfur foods that you need to be careful with folic acid supplementation. Can someone summarize what that issue is? I am heterozygous for C677T, which I understand... (more)
Hi, I just got my 23andme results back and need some help understanding what the heck I can do... 1. I have a CBS mutation, which is confusing. On one hand, I have always had joint pain & stiffness, so I'm not surprised that I have a sulfur... (more)
I just started taking Sam-e today, along with methylcobalamin. I am taking 200 mg, will soon take 400 mg. How long does it take to increase neurotransmitters serotonin and dopamine on this stuff?
I've seen a few questions and answers touch on this, but I'm curious: Has anyone been treated for hetero- or homozygous methylenetetrahydrofolate reductase (MTHFR, aka "Motherf***er) enzyme deficiency? If so, what symptoms were you having... (more)
What is the easiest way to figure out the minimal effective dose of supplementation and dietary change to adjust for the following genetics? It seems that I have minor defects, but nothing serious. All other things being equal, I would love to... (more)
I'v spent an enormous amount of time and read all kinds of theoretical info about methylation causing excess sulfur and ammonia. Does anyone here have that issue or is this all ivory tower theoretical stuff? Ever since going paleo and... (more)