4

votes

Dr K, do you have any suggestions for ADD?

Answered on September 12, 2014
Created April 25, 2011 at 4:06 AM

I stopped life long crushing depression by doing an autoimmune version of the paleo diet (back/neck pain largely went away as well). I also more then cut in half my generalized anxiety (both along w/ADD diagnosed at Amen Clinic). However, my ADD has only been tempered somewhat. I know that there are up to 7 genes involved in ADD so perhaps it's just something I'm stuck with? My cortisol level is flipped and is below average in morning and above average at night. I used to also have low testosterone but have more than tripled it into the low/average level. I really dig the answers you have given on this website and thought I'd run this by you. I am also asking as I'm sure there are others in the paleohacks community who could benefit.

246ebf68e35743f62e5e187891b9cba0

(21430)

on April 23, 2012
at 09:45 PM

being a sufferer of ADHD throughout all of my 34 years on this earth, low carb and gluten free at least allows me to employ coping mechanisms, such as being able to interrupt my brain-mouth connection (blurting out, interrupting, etc) and being able to process and perform even the most tedious tasks. If I was "on my game" back when I was pre-paleo, I could focus about 50% of the time. I would say by now it's closer to 75-80%, even on bad days.

5437163ddf70d4532f196bfb4333753e

(3614)

on April 23, 2012
at 08:27 PM

I totally agree. Dr. Lipton came to speak numerous times when I was at chiropractic college. Interesting guy. What I love about his work is the premise that the cell membrane is in control of the genes, not vice versa. I like the notion that things are not pre-destined as a result of our DNA. Our thoughts and actions MATTER!

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on August 17, 2011
at 01:07 PM

It's critical to understanding in my view and forms the basis of paleo 3.0

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on August 17, 2011
at 01:06 PM

Just wrote about neurotransmitters and the gut around aug 13th.

B58511bcd1ecc0dd4ad8130859513c81

(430)

on August 17, 2011
at 05:31 AM

I have a hard time reading through your entire answer, especially with no separations in it, but then again I have ADD so thats probably why!

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:53 PM

Thanks for your answer Dr K. My depression kicked in at age 14 but now at age 30 it is gone due to the autoimmune Paleo diet. If I eat anything that causes me inflammation it will come back. My anxiety has also dropped significantly since going autoimmune Paleo. So are you basically saying that there is no solution once someone is born with ADD? Mine is much better on Paleo, I would say it is cut in half. However it is still a huge struggle. I am hyper sensitive to stimulants so they ADD meds raise my anxiety through the roof. I guess I'll continue my Zen meditations and hope for the best

25ed4acfb632d928507f8673bcb0923a

(650)

on April 25, 2011
at 05:32 PM

Reference for this?

742ff8ba4ff55e84593ede14ac1c3cab

(3536)

on April 25, 2011
at 04:45 PM

Can't wait for your blog Dr. K!

1e58ba5c171a122541d8b4873f604327

(229)

on April 25, 2011
at 03:43 PM

Thanks for taking the time to post this! Sign me up as a blog follower when you get it off the ground. Dr K. are you familiar with the PANDAS hypothesis, and if so what do you think?

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 03:27 PM

Candles even turn off melatonin

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 03:26 PM

I do think the brain gut axis worsens ADD and carbs are a huge issue why....grains too. But that is another post

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 03:00 PM

Not yet. After I get back from my conference this week on stem cells and telomeres it's on like donkey kong. I have made a list of things I am going to post about but one thing I have decided is to make Fridays open source Fridays......I'm going to leave it to my readership the topic they want to hear about......if itsngood and I have insight on it I'll give it up. If not they will endure more ramblings of a digital surgeon

Cf5c9ba3c06cf300ae23c52778dfd317

(545)

on April 25, 2011
at 02:45 PM

Dr. K, have you started your blog yet?

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 02:18 PM

Time to get back to surgery.......

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:50 AM

Im guessing that perhaps blue light and its effects on hormone regulation could be causing issues. I had a 10 day period when my GF was out of town that I tried to go as "caveman" as possible. No artificial light after sundown (candles), and no internet or TV (normally my one "addiction.") and I put a message on my cell that I was unavailable for the next 10 days. I got more done in those 10 days then I normally get done in over a month. It's difficult to keep this going indefinitely, perhaps I should try some of the blue light blocking glasses...

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:44 AM

...mundane tasks such as errands or chores around the house but doesnt really focus me enough for tasks involving intense thought.

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:43 AM

I glanced at some of the articles and it's interesting stuff. I was tested by a naturopath and had low dopamine, low seratonine, low glutamate but HIGH histamine. This was when I was eating regular Paleo. Ive also tested allergic to many foods. I feel much better eating autoimmune version of Paleo (stopped my depression totally). I also take probiotics and did a few rounds of Now Foods Super Enzymes. Also its interesting that she has an article on Endocannabinoids as I recently got a medical card (never smoked before this) and Sativa does seem to help alot. The problem is it helps..

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:25 AM

"autoimmune version of the paleo diet." I don't eat gluten, eggs, nightshades, dairy, legumes or any trace of soy.

D10ca8d11301c2f4993ac2279ce4b930

(5242)

on April 25, 2011
at 04:42 AM

Get off wheat. http://www.corepsychblog.com/2008/11/brain-add-gluten-are-connected-dr-tom-obryans-fall-lectures/#axzz1KVU30uBT

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 04:16 AM

Thanks for the link. I already eat Robb Wolf's autoimmune Paleo diet. I supplement with liver powder, vitamin d, fish oil, vitamin c and l- arginine.

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7 Answers

4
Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 02:18 PM

ADD is a disorder with no known cause but with several very interesting associations. I personally believe based upon my readings that it is an epigenetic condition caused by hypermethylation of genes involved in dopamine transport proteins. That does not end the story. I think the disease is made worse as one ages because patients also have comorbid sleep disorder. To date no one scientist can accurately state what the purpose of sleep is but there are many theories. My belief is that sleeps main purpose is to allow the brain to thin slice data coded that is "hard.". What? If you learn something tied to emotion or that is stressed or learned in stress this hard data is thin sliced into our association cortex for use in the forebrain bundle to help us build a relational database of our envirnoment that will help us understand our surroundings and make better predictions on how to live within it and how to associate things to other soft and hard concepts. Sleep in humans is set to a circadian rhythm of close to eight hrs. Humans need that amount of sleep due to the shear size and number of nerve cells. It takes a lot of time for the brain to perform housekeeping on these cells for plasticity of learning and to strengthen the distal synapses where 99% of energy utilization occurs during awakeness. The protein transcription occurs and has to travel substantial distances to replenish and strengthen the machinery. In ADD you have already defective machinery and disordered sleep. A double whammy. This is why ADD seems to get worse as we age and usually ends in depression but begins with problems of inattention to our surroundings and impulsivity. This makes it tough to build a relational database of our environment. Since the environment is not properly coded for in memory extra circuitry is need to bridge gaps. Serotonin becomes a big problem because it get overwhelmed since the dopamine tracts can't code memory in the medial temporal lobe. This leads to an imbalance of serotonin and eventual depression and worsens the issue further. Depression becomes the main issue later not impulsivity because their is a temporal issue for building your three dimensional reality of the world. The more disordered it becomes the more dysfunction the animal is and the more depression results because reward circuits are not naturally selected for when our surroundings can't be coded properly. Failure circuits become hyperactive. This is seen in PET scans of older ADD patients. The rest here is from wiki. It includes the gene variants that we see in kids with this. The ADD subtypes that respond to adderal make up a very small percentage (9%) of cases due to a specific epigentic change in LPHN3. That it why i am not a fan of treating all kids with stimulants. Stimulants also have big unintended side effect of uncoupling metobolism from leptin signalling so these kids always grow up with weight and thyroid issues compounding their clinical picture. The worst reverse T3 levels i have seen are in ADD adults. That makes dealing with their diets real tough. The data on transporters is copied from wiki.....enjoy! Twin studies indicate that the disorder is highly heritable and that genetics are a factor in about 75 percent of all cases.[25] Hyperactivity also seems to be primarily a genetic condition; however, other causes do have an effect.[42] Researchers believe that a large majority of ADHD cases arise from a combination of various genes, many of which affect dopamine transporters. Candidate genes include ??2A adrenergic receptor, dopamine transporter, dopamine receptors D2/D3,[43] dopamine beta-hydroxylase monoamine oxidase A, catecholamine-methyl transferase, serotonin transporter promoter (SLC6A4), 5HT2A receptor, 5HT1B receptor,[44] the 10-repeat allele of the DAT1 gene,[45] the 7-repeat allele of the DRD4 gene,[45] and the dopamine beta hydroxylase gene (DBH TaqI).[46] A common variant of a gene called LPHN3 is estimated to be responsible for about 9% of the incidence of ADHD, and ADHD cases where this gene is present are particularly responsive to stimulant medication.[47]

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:53 PM

Thanks for your answer Dr K. My depression kicked in at age 14 but now at age 30 it is gone due to the autoimmune Paleo diet. If I eat anything that causes me inflammation it will come back. My anxiety has also dropped significantly since going autoimmune Paleo. So are you basically saying that there is no solution once someone is born with ADD? Mine is much better on Paleo, I would say it is cut in half. However it is still a huge struggle. I am hyper sensitive to stimulants so they ADD meds raise my anxiety through the roof. I guess I'll continue my Zen meditations and hope for the best

742ff8ba4ff55e84593ede14ac1c3cab

(3536)

on April 25, 2011
at 04:45 PM

Can't wait for your blog Dr. K!

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 03:00 PM

Not yet. After I get back from my conference this week on stem cells and telomeres it's on like donkey kong. I have made a list of things I am going to post about but one thing I have decided is to make Fridays open source Fridays......I'm going to leave it to my readership the topic they want to hear about......if itsngood and I have insight on it I'll give it up. If not they will endure more ramblings of a digital surgeon

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 03:26 PM

I do think the brain gut axis worsens ADD and carbs are a huge issue why....grains too. But that is another post

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 02:18 PM

Time to get back to surgery.......

Cf5c9ba3c06cf300ae23c52778dfd317

(545)

on April 25, 2011
at 02:45 PM

Dr. K, have you started your blog yet?

1e58ba5c171a122541d8b4873f604327

(229)

on April 25, 2011
at 03:43 PM

Thanks for taking the time to post this! Sign me up as a blog follower when you get it off the ground. Dr K. are you familiar with the PANDAS hypothesis, and if so what do you think?

B58511bcd1ecc0dd4ad8130859513c81

(430)

on August 17, 2011
at 05:31 AM

I have a hard time reading through your entire answer, especially with no separations in it, but then again I have ADD so thats probably why!

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on August 17, 2011
at 01:06 PM

Just wrote about neurotransmitters and the gut around aug 13th.

3
8a4ce6a9e1ab27616920b828df08b259

(354)

on April 25, 2011
at 03:37 PM

I also have (bad) ADD and eat paleo, and take extended release methylin. I've noticed that I don't need as much medicine, going paleo, but still need it. Medicine and diet just aren't cure-alls. There are a lot of bad habits we have. My suggestion is to break your addiction to the internet. With ADD, it's extra hard to tear away from the computer, with all the stimulation. I am so much more functional when I don't use the computer. I use my phone to look stuff up, and that's a bit better. Anyway, try going internet free for a couple weeks and see how you do.

3
1cbb6b2a813475d6c0b17fd5e898dc50

on April 25, 2011
at 10:36 AM

I have recently started reading about epigenetics and urge everyone to do the same. Spontaneous Evolution by Bruce Lipton is one of the best books I have read in a long time. I'm still reading it and it is pretty deep so I don't understand all of the science of it but basically WE are in control of our genes....our genes aren't written in stone like we once thought! Human mental abilities are EXTREMELY powerful and should never be overlooked.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on August 17, 2011
at 01:07 PM

It's critical to understanding in my view and forms the basis of paleo 3.0

5437163ddf70d4532f196bfb4333753e

(3614)

on April 23, 2012
at 08:27 PM

I totally agree. Dr. Lipton came to speak numerous times when I was at chiropractic college. Interesting guy. What I love about his work is the premise that the cell membrane is in control of the genes, not vice versa. I like the notion that things are not pre-destined as a result of our DNA. Our thoughts and actions MATTER!

3
77ecc37f89dbe8f783179323916bd8e6

(5002)

on April 25, 2011
at 06:10 AM

I'd like to second the request. I have ADD and take a lot of Adderall in order to study (I'm a 29 year old PhD student). I'd like more information on the effects of Adderall and possible alternative treatments. So far, the ADD-related information available on this site is unsatisfactory.

3
Be1dbd31e4a3fccd4394494aa5db256d

(17969)

on April 25, 2011
at 04:13 AM

I'm sure Dr. K will have some stellar advice as usual, but I'm going to use this to spread the best paleo-friendly psychiatry blog ever. http://evolutionarypsychiatry.blogspot.com/search?q=add

Cheers. Looks like the conclusion is "go paleo!" and additionally "get all of them nutrients!"

25ed4acfb632d928507f8673bcb0923a

(650)

on April 25, 2011
at 05:32 PM

Reference for this?

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:44 AM

...mundane tasks such as errands or chores around the house but doesnt really focus me enough for tasks involving intense thought.

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 04:16 AM

Thanks for the link. I already eat Robb Wolf's autoimmune Paleo diet. I supplement with liver powder, vitamin d, fish oil, vitamin c and l- arginine.

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:43 AM

I glanced at some of the articles and it's interesting stuff. I was tested by a naturopath and had low dopamine, low seratonine, low glutamate but HIGH histamine. This was when I was eating regular Paleo. Ive also tested allergic to many foods. I feel much better eating autoimmune version of Paleo (stopped my depression totally). I also take probiotics and did a few rounds of Now Foods Super Enzymes. Also its interesting that she has an article on Endocannabinoids as I recently got a medical card (never smoked before this) and Sativa does seem to help alot. The problem is it helps..

B22e5946e28a1845a6006737e59edfc6

(2437)

on April 25, 2011
at 05:50 AM

Im guessing that perhaps blue light and its effects on hormone regulation could be causing issues. I had a 10 day period when my GF was out of town that I tried to go as "caveman" as possible. No artificial light after sundown (candles), and no internet or TV (normally my one "addiction.") and I put a message on my cell that I was unavailable for the next 10 days. I got more done in those 10 days then I normally get done in over a month. It's difficult to keep this going indefinitely, perhaps I should try some of the blue light blocking glasses...

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on April 25, 2011
at 03:27 PM

Candles even turn off melatonin

1
13c5a9f1678d75b93f269cdcf69f14d5

(2339)

on April 25, 2011
at 03:17 PM

Have you looked into salicylates and amines also? Ie the failsafe or feingold diet?

0
D826ee7c5f65d509348f7fe8aeeafdd4

(368)

on April 23, 2012
at 09:21 PM

I also have ADD - it would take me probably the rest of this week to read all the answers in here. I've never considered medicine for it until recently.

Is there any research about environment/atmosphere/time of day that triggers ones ADD. For example, I can quite comfortably read a book early in the morning, in a coffee shop, with a strong brew. Doing so now, end of day at my office is pretty much impossible...

Is there any validity in brain exercises to focus more/overcome ADD?

246ebf68e35743f62e5e187891b9cba0

(21430)

on April 23, 2012
at 09:45 PM

being a sufferer of ADHD throughout all of my 34 years on this earth, low carb and gluten free at least allows me to employ coping mechanisms, such as being able to interrupt my brain-mouth connection (blurting out, interrupting, etc) and being able to process and perform even the most tedious tasks. If I was "on my game" back when I was pre-paleo, I could focus about 50% of the time. I would say by now it's closer to 75-80%, even on bad days.

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