1

votes

block prostaglandin with ibuprofen / menstruation issues

Answered on August 19, 2014
Created May 24, 2013 at 5:08 PM

NSAIDS are best avoided due to gut damage.

I have autoimmune, so that's a double no-no for me. Yet, I've always had extremely heavy periods. About 5 years ago, my OBGYN told me to start taking 3 Advils every 4 hours, 2 days before my period through the first couple of days (about 4 days of dosing).

It's magic. I wear a pad for over-flow but it means changing a tampon once an hour rather than being house-bound. I took big pharma hormones for 20 years (still bleed on non-period days, 9 day periods with maybe 2 weeks off, if I were lucky). NSAIDS help better. I do Autoimmune Protocol (came to Paleo after months of following my doctor's autoimmune protocol, which is stricter). The condition did not improve on AI or on my doc's stricter protocol.

This is a common issue in my family. Several had hysterectomies in their 20s (including my maternal grandmother) to stop it. An aunt bled to death with this (she lived remotely and didn't have access to emergency help).

My question:

Are their any great alternatives for people genetically wired this way?

I'm not keen on surgical procedures. I'd prefer to find supplement or food-based prostaglandin blockers to help THIS situation. If ibuprofen can help, surely there's something I'm missing!

To NSAID or not to NSAID? ...Other options?

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on June 27, 2013
at 02:08 PM

Lily, I agree that your situation isn't normal. However, with that much protein, it is unlikely that you could go into ketosis.

67871ef2326f29da48f1522827fc0f80

(704)

on June 27, 2013
at 02:25 AM

I think your reaction is normal--at least I've seen this in women around the net whether paleo or other ketogenic folks. I eat at least 1g protein per lb but when lifting can easily do 1.5g/lb. My situation isn't normal. While I'll do VLC for a few weeks at a time (does shed fat!), I sustained 50g carbs/ day for almost a year with no change in heavy bleeding. Again, my situation isn't normal and requires intervention but most women who share seem to have easier periods.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on June 27, 2013
at 12:29 AM

Interesting. I wonder if you were eating too much protein to be in ketosis? I did vlc for 6weeks back in 2011 with no change in my cycle at all, but I was eating too much protein to be in ketosis. I was also counting calories and felt pretty awful. This time, I am doing it differently and getting different results.

68655ec9711d207d69a63ebf96b37573

on June 26, 2013
at 10:17 PM

When I did VLC (30g carbs/day) stopped my period dead! I'd love to be able to do VLC (under 50g) and not get hypothyroid but my body doesn't seem to be able to deal with it

68655ec9711d207d69a63ebf96b37573

on May 26, 2013
at 05:36 PM

IUD or IUS? An IUD will make your issues worse, an IUS better. Not sure about the NSAIDs. Probably worse when ingested? Personally I'd rather a little monthly damage to the guy than deal with my menstrual issues. It literally knocks me out for the entire day

67871ef2326f29da48f1522827fc0f80

(704)

on May 26, 2013
at 03:03 AM

Interesting idea about the injectables. I wonder if the product still affects the gut (as it's 'everywhere' if injected) or if NSAIDS are only deleterious WHEN INGESTED? I'm a wall of ignorance here (why I asked!). I would never get an IUD. It horrifies me to think of it but that may be because my aunt almost died trying that to help her. Could be bad luck but ::shudders:: She ended up with hysterectomy, too. BECAUSE of IUD (used to help this issue).

67871ef2326f29da48f1522827fc0f80

(704)

on May 26, 2013
at 03:00 AM

Misunderstood: aunt on mother's side. I'm half-Irish (2nd generation American) and half Russian Jew. We're far from indigenous! But that auntie married a 'real indian' and died on the res, yes. I guarantee I grew up hunting and gathering with the best of them. I can go out in the woods now and collect edibles and kill any animal you want and dress it out (butcher). Last year, I ripped the head off a rabbit to kill it. Most ladies these days don't do that but it's how I was raised. Hell, I was wrangling a snake by hand today, too. It was in the pasture.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on May 24, 2013
at 10:40 PM

If you aren't planning on having children, uterine ablation may be an option.

32652cb696b75182cb121009ee4edea3

(5802)

on May 24, 2013
at 09:21 PM

also .. you mentioned your mother on the res in Ok - are you native american? cherokee? my family is also from OK, cherokee (and choctaw, mixed). i have seen a few studies (wish I could remember where) on how different ethnicities had longer/harder cycles. Perhaps related to the idea that those of us closer in DNA to a hunter-gatherer ancestor are more drastically impacted by western diet.

32652cb696b75182cb121009ee4edea3

(5802)

on May 24, 2013
at 09:00 PM

yeah, it's a genetic thing, the iron. my luck it worked in my favor for once. :) before I started menses I was chronically constipated. I don't even bother with tampons. they're useless for me. I also bleed rectally bc of endometriosis in my colon, so there's no helping that one. i'm going to file that preemptive ibuprofen thing in my head for my daughter, who is starting to experience all the joy of this!

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 08:37 PM

Oh, and my periods now are only 7 days, once a month, used to be 2 nine-day periods a month but that's because I use soya (non-paleo but if drinking 3C of unsweetened, organic soya can keep me off pharma hormone replacements to regulate and shorten my period, I'm game). It doesn't help the flow, though. Ibuprofen does.

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 08:35 PM

That's great that something works for you! As stated, for me the lower flow is one tampon per hour, so it's no fun. Unlike you, I've always had iron deficiencies (NO KIDDING?!) and have taken RX supplements some years. Paleo fixed my years of misdiagnosed Celiac, therefore my other malabsorption issues almost went away (I still have to work hard to get a lower range normal potassium, I think that may be because I don't eat salt a lot, unless craving it). It did zero for flow. They've never suggested D&C for me, although my mother used to get those. I've never had a child.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on May 24, 2013
at 06:32 PM

Gotcha! I don't have the bleeding issues that you do, just the cramping.

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 06:26 PM

Yeah, we're not talking cramps. And I drink green tea -- way more, for what that's worth (daily). I commented on the reply above so I won't repeat.

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 06:26 PM

I get checked every year since before I could drive (in the US, age 16). I've gone to 3 different doctors and this 1 is the only who offered a non-hormonal idea. Acetaminophen doesn't block prostaglandin. I've searched menstruation and all I see is how great everybody does with going Paleo. It's about prostaglandin blocking FLOW (what I do is called *hemorrhaging*). Solid months of 100% autoimmune protocol (stricter) should have shown measurable results, that was going to help.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on May 24, 2013
at 05:30 PM

Have you been checked for fibroids or endometriosis?

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on May 24, 2013
at 05:29 PM

I'd love to know if anyone has solved this yet, I still need to use a pain reliever ( I use acetaminophen, since it seems to have a slightly lesser effect on gut flora.) Search for "menstrual cramps" and you will see some other questions on this topic.

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4 Answers

1
32652cb696b75182cb121009ee4edea3

(5802)

on May 24, 2013
at 08:14 PM

I had to have a D&C (under full anesthesia) after a particularly bad miscarriage, and the year or 2 after that was AMAZING. Normal period for the first time ever. 2 years later I got pregnant, and it was back to the monstrous bleeding after that.

I've had 5 pregnancies, and my cycle has been just as awful after the 4 healthy deliveries. Only the miscarriage with D&C changed it.

Paleo has 100% helped my cramps/pms, but the heavy bleeding remains. However, mine has gone down to only 2 days of heaviness (instead of 4), with 4 days of more "normal."

If I get to the point where I can't take it anymore, I've decided I'll go in and see if I can talk them into another D&C. Ironically, however, I also have excessively high iron, so it turns out that heavy bleeding once a month is good for me.

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 08:35 PM

That's great that something works for you! As stated, for me the lower flow is one tampon per hour, so it's no fun. Unlike you, I've always had iron deficiencies (NO KIDDING?!) and have taken RX supplements some years. Paleo fixed my years of misdiagnosed Celiac, therefore my other malabsorption issues almost went away (I still have to work hard to get a lower range normal potassium, I think that may be because I don't eat salt a lot, unless craving it). It did zero for flow. They've never suggested D&C for me, although my mother used to get those. I've never had a child.

32652cb696b75182cb121009ee4edea3

(5802)

on May 24, 2013
at 09:00 PM

yeah, it's a genetic thing, the iron. my luck it worked in my favor for once. :) before I started menses I was chronically constipated. I don't even bother with tampons. they're useless for me. I also bleed rectally bc of endometriosis in my colon, so there's no helping that one. i'm going to file that preemptive ibuprofen thing in my head for my daughter, who is starting to experience all the joy of this!

32652cb696b75182cb121009ee4edea3

(5802)

on May 24, 2013
at 09:21 PM

also .. you mentioned your mother on the res in Ok - are you native american? cherokee? my family is also from OK, cherokee (and choctaw, mixed). i have seen a few studies (wish I could remember where) on how different ethnicities had longer/harder cycles. Perhaps related to the idea that those of us closer in DNA to a hunter-gatherer ancestor are more drastically impacted by western diet.

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 08:37 PM

Oh, and my periods now are only 7 days, once a month, used to be 2 nine-day periods a month but that's because I use soya (non-paleo but if drinking 3C of unsweetened, organic soya can keep me off pharma hormone replacements to regulate and shorten my period, I'm game). It doesn't help the flow, though. Ibuprofen does.

67871ef2326f29da48f1522827fc0f80

(704)

on May 26, 2013
at 03:00 AM

Misunderstood: aunt on mother's side. I'm half-Irish (2nd generation American) and half Russian Jew. We're far from indigenous! But that auntie married a 'real indian' and died on the res, yes. I guarantee I grew up hunting and gathering with the best of them. I can go out in the woods now and collect edibles and kill any animal you want and dress it out (butcher). Last year, I ripped the head off a rabbit to kill it. Most ladies these days don't do that but it's how I was raised. Hell, I was wrangling a snake by hand today, too. It was in the pasture.

0
Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on June 26, 2013
at 08:43 PM

I just went ketogenic 3 weeks ago and noticed that my period was much lighter, and slightly less crampy this month.

I keep my carbs under 40 gms and my protein at 1 gm per kilogram of body weight. No calorie counting.

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on June 27, 2013
at 12:29 AM

Interesting. I wonder if you were eating too much protein to be in ketosis? I did vlc for 6weeks back in 2011 with no change in my cycle at all, but I was eating too much protein to be in ketosis. I was also counting calories and felt pretty awful. This time, I am doing it differently and getting different results.

68655ec9711d207d69a63ebf96b37573

on June 26, 2013
at 10:17 PM

When I did VLC (30g carbs/day) stopped my period dead! I'd love to be able to do VLC (under 50g) and not get hypothyroid but my body doesn't seem to be able to deal with it

Ce41c230e8c2a4295db31aec3ef4b2ab

(32564)

on June 27, 2013
at 02:08 PM

Lily, I agree that your situation isn't normal. However, with that much protein, it is unlikely that you could go into ketosis.

67871ef2326f29da48f1522827fc0f80

(704)

on June 27, 2013
at 02:25 AM

I think your reaction is normal--at least I've seen this in women around the net whether paleo or other ketogenic folks. I eat at least 1g protein per lb but when lifting can easily do 1.5g/lb. My situation isn't normal. While I'll do VLC for a few weeks at a time (does shed fat!), I sustained 50g carbs/ day for almost a year with no change in heavy bleeding. Again, my situation isn't normal and requires intervention but most women who share seem to have easier periods.

0
68655ec9711d207d69a63ebf96b37573

on May 24, 2013
at 08:33 PM

Oh, menstrual woes. I get it too, the whole lot - fever, sweating, dizziness, vomiting, diarrhea, fainting. Oh, plus the agonizing contractions, of course I think I've been to the ER at least 4 times in the past 8 years, when it came on suddenly and in public.

Paleo very much reduced it for me as is it reduces overall inflammation. I went from 3 hours of hell and wiped out for the day, every single month, to bad pains roughly every 6 months and medium cramps on the other times

Personally, I take 2 diclofenac a day for 3 days before my period. It's so much better for dsymenorrhea than ibuprofen etc. I'd rather damage my gut a little than deal with the agony and potential trip to the ER.

I have been given injectable anti-inflammatories before but I don't know if they were steroidal or non-steroidal. Oxygen helps too (as the pain is caused by the inflamed contracting uterine muscles not getting enough oxygen. I can't do any kind of aerobic workout before my period, either)

Maybe you can persuade a doctor to give you the drugs with needles attached, and inject yourself?

I don't have heamorrhaging issues but have a friend who does, and she got the Mirena IUS - eliminated the issue

68655ec9711d207d69a63ebf96b37573

on May 26, 2013
at 05:36 PM

IUD or IUS? An IUD will make your issues worse, an IUS better. Not sure about the NSAIDs. Probably worse when ingested? Personally I'd rather a little monthly damage to the guy than deal with my menstrual issues. It literally knocks me out for the entire day

67871ef2326f29da48f1522827fc0f80

(704)

on May 26, 2013
at 03:03 AM

Interesting idea about the injectables. I wonder if the product still affects the gut (as it's 'everywhere' if injected) or if NSAIDS are only deleterious WHEN INGESTED? I'm a wall of ignorance here (why I asked!). I would never get an IUD. It horrifies me to think of it but that may be because my aunt almost died trying that to help her. Could be bad luck but ::shudders:: She ended up with hysterectomy, too. BECAUSE of IUD (used to help this issue).

0
A2b91be08dc87a1f779b500ae662b9a9

on May 24, 2013
at 05:56 PM

I had tremendous luck with green tea and oolong tea, about 1 tbsp. daily. Some days I steep the same tea up to three times a day. I drink it daily, all month long, and when my period now comes, it's little to moderate pain, certainly not the debilitating pain it once was.

67871ef2326f29da48f1522827fc0f80

(704)

on May 24, 2013
at 06:26 PM

Yeah, we're not talking cramps. And I drink green tea -- way more, for what that's worth (daily). I commented on the reply above so I won't repeat.

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