2

votes

What will be the next breakthrough discovery?

Answered on August 19, 2014
Created November 25, 2011 at 4:59 AM

Leptin, arguably the most important hormone in our bodies, wasn't discovered until 1994. Uncoupling proteins(2-5) weren't discovered until the late 90s and their functions were being figured out in the early- mid 2000s. Pretty amazing considering how advanced we always think that we are.

Will there be any more giant discoveries like these?

If so, what functions could these yet to be discovered hormones/proteins/etc fulfill? or what answers could they provide?

edit: what answers/mechanisms should be taking research priority?

499f188c87c6980742b9ba98caa6f563

(683)

on November 28, 2011
at 02:52 PM

These days I seem to be overdosing on confusin.

0bc6cbb653cdc5e82400f6da920f11eb

(19245)

on November 27, 2011
at 09:40 PM

Humor deficiency is a common problem in diet discussions :)

24df4e0d0e7ce98963d4641fae1a60e5

on November 27, 2011
at 09:36 PM

Awww ... downvoted. Gee, some people have no sense of humor.

24df4e0d0e7ce98963d4641fae1a60e5

on November 27, 2011
at 09:36 PM

Awww ... some people have no sense of humor!

Da3d4a6835c0f5256b2ef829b3ba3393

on November 27, 2011
at 06:13 PM

I think you're onto something!

96440612cf0fcf366bf5ad8f776fca84

(19463)

on November 27, 2011
at 03:33 PM

+100 (if it were possible) for bacon anything.

5ef574d7893bc816ec52e04139e9bc09

(6097)

on November 27, 2011
at 12:29 AM

http://commonfund.nih.gov/hmp/

Dc5144de5078c44a2b106ff25778fd3d

(308)

on November 26, 2011
at 08:19 PM

In my house, it seemingly does.

77877f762c40637911396daa19b53094

(78467)

on November 26, 2011
at 08:07 PM

+1,Paragraph #2 real strong.

A968087cc1dd66d480749c02e4619ef4

(20436)

on November 25, 2011
at 06:46 PM

+1 for the Beatles

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8 Answers

7
B3e7d1ab5aeb329fe24cca1de1a0b09c

(5242)

on November 25, 2011
at 06:01 AM

Yes. Lots.

Gut flora.

5ef574d7893bc816ec52e04139e9bc09

(6097)

on November 27, 2011
at 12:29 AM

http://commonfund.nih.gov/hmp/

6
Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on November 27, 2011
at 02:57 PM

The brain gut axis is the next frontier......and after that will be sleep and light cycle biology. All are tied together in tight regulatory control at the hypothalamus. There is much yet to be discovered and even more to understand how the entire system regulates itself.

Da3d4a6835c0f5256b2ef829b3ba3393

on November 27, 2011
at 06:13 PM

I think you're onto something!

3
Medium avatar

on November 26, 2011
at 02:09 AM

There will be many more huge discoveries in health and nutrition. To add to your list, PQQ, a new B vitamin, was just discovered in 1979 and there's still a lot we don't know about it. As you said, leptin is another example. It's a master controller of energy and metabolism in the body, yet we just recently discovered it, so imagine how much we still don't know about it? Imo, the two big areas that we still don't know a lot about are evolutionary biology and microbiology, specifically, our gut bacteria. I think the most important part of our body that we don't know much about is all the species of bacteria living in our gut and how they interact with our immune system, nervous systems, and more. This to me is the last unknown frontier relative to other areas of research. For example, we only recent have seen many studies showing links between gut bacteria and brain development, depression and anxiety, obesity, autoimmune disease, and more. Also, this is the part of our bodies that is changing the most and still evolving, since it's debatable whether or not humans as a species are still evolving to a significant degree. We've evolved along with these bacteria, so one can only imagine all the ways our bodies have adapted to accommodate them and likewise all the ways they evolved to provide us benefits in order to survive inside us. That's why fecal bacteriotherapy is becoming more common and showing to be very successful, more aspects of our health are dependent on our gut bacteria than we know and more diseases can be cured by balancing our gut bacteria than we know.

3
25b139cc1954456d9ea469e40f984cd3

on November 25, 2011
at 05:44 AM

No, never.

"Guitar Groups are on their way out, Mr. Epstein...the Beatles have no future in show business..."

--Decca Records rejecting the Fab Four, 1962--

A968087cc1dd66d480749c02e4619ef4

(20436)

on November 25, 2011
at 06:46 PM

+1 for the Beatles

2
Da3d4a6835c0f5256b2ef829b3ba3393

on November 26, 2011
at 07:10 PM

Bacon that, once cooked, flies directly into your mouth.

96440612cf0fcf366bf5ad8f776fca84

(19463)

on November 27, 2011
at 03:33 PM

+100 (if it were possible) for bacon anything.

Dc5144de5078c44a2b106ff25778fd3d

(308)

on November 26, 2011
at 08:19 PM

In my house, it seemingly does.

2
5ef574d7893bc816ec52e04139e9bc09

(6097)

on November 26, 2011
at 04:12 PM

Human Microbiome Project.

This will almost definitely expand our knowledge of the gut and its flora.

2
Medium avatar

on November 25, 2011
at 05:41 AM

I checked. Nope, no more discoveries in store. The life force has stalled, status quo forever.

But of course there'll be new discoveries. As long as there are individuals willing to hang out with provocative questions of the kind that wake them up at night and keep them from being satisfied in the grooves cut by conventional thinking.

And just so we don't get all Utopian or anything: many of tomorrow's new discoveries will be as nonsensical or dangerous as yesterday's. Like Ancil Keys' "discovery" of the "fact" that dietary fat is "bad for health."

77877f762c40637911396daa19b53094

(78467)

on November 26, 2011
at 08:07 PM

+1,Paragraph #2 real strong.

1
24df4e0d0e7ce98963d4641fae1a60e5

on November 27, 2011
at 08:17 PM

I'm hoping scientists can discover truthtin, factin, dogmasuppressin and lackohypin in the brains of diet book authors and nutrition gurus.

0bc6cbb653cdc5e82400f6da920f11eb

(19245)

on November 27, 2011
at 09:40 PM

Humor deficiency is a common problem in diet discussions :)

24df4e0d0e7ce98963d4641fae1a60e5

on November 27, 2011
at 09:36 PM

Awww ... some people have no sense of humor!

24df4e0d0e7ce98963d4641fae1a60e5

on November 27, 2011
at 09:36 PM

Awww ... downvoted. Gee, some people have no sense of humor.

499f188c87c6980742b9ba98caa6f563

(683)

on November 28, 2011
at 02:52 PM

These days I seem to be overdosing on confusin.

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