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Relationship between manganese and magnesium

Commented on October 03, 2013
Created October 03, 2013 at 3:01 AM

I did some research and found that manganese might be a good supplement to try for my crackling joints.

I already take Magnesium..should I take manganese with magnesium. It seems like a lot of foods that are high in manganese are also high in magnesium. So on paper it seems to make sense to take them together, but I can't find anything on Google.

I'm very OCD about whether my vitamins & minerals are actually being absorbed. I know a lot of minerals fight for absorption and can cancel each other out.

Background/details: after some research I suspected that I might have pyroluria. Long story short, three weeks ago I dropped my krill oil supplementation & picked up Evening primrose oil, zinc picolonate, magnesium citrate, kelp, selenium, B6, & P5P. I've felt much better in the past two weeks; I have always had a small patch of rosacae at the crest of my nose..it's gone, dry scalp & dandruff..gone, depression..gone, seasonal allergy symptoms..gone. acne...still there, actually seemed to get worse at first but has calmed down the past couple of days. Crackling joints; much, much worse.

0b4326a4949718451a8571b82558dc10

(2349)

on October 03, 2013
at 02:43 PM

Great article!..apparently B6 & magnesium are antagonists of Manganese. I think I'm going to drop my magnesium & If that doesn't get results i'll try supplementing with manganese at night when I take my zinc (I usually take my B vitamins and magnesium in the morning) ....I appreciate all your help! I do eat a lot of coconut meat which is loaded in manganese, so hopefully I won't have to end up supplimenting.

0b4326a4949718451a8571b82558dc10

(2349)

on October 03, 2013
at 02:22 PM

Pyroluria symptoms diagnose all these supplements. & I have a lot of symptoms...

http://www.primalbody-primalmind.com/?p=398

trust me, I'd like to think my diet could do everything, but I have issues like adult acne, seasonal dry eyes & cold fingers/toes that even paleo has yet to fix. I'm kindof desperate & I'll try anything.

0b4326a4949718451a8571b82558dc10

(2349)

on October 03, 2013
at 02:15 PM

great information. thanks!

32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on October 03, 2013
at 12:53 PM

Holy supplementation, Batman! Does a rough tally of your diet suggest you need all these?

543a65b3004bf5a51974fbdd60d666bb

(4493)

on October 03, 2013
at 07:20 AM

"(manganese) shortage can make the ligaments too stretchy and loose"...i've been reading similar, so may be in your case the cracking is related, esp if your joints feel too "loose". google searches relating to manganese deficiency & joints, include joint dislocations (particularly knees). here's one site acu-cell.com/femn

543a65b3004bf5a51974fbdd60d666bb

(4493)

on October 03, 2013
at 07:12 AM

okay, sounds like you have a bit more going on then

0b4326a4949718451a8571b82558dc10

(2349)

on October 03, 2013
at 06:27 AM

I missed your "got good ref links" suggestion...I have found claims but they're few and far between. Here's one example;

"When I told him about my joints he said it was likely a maganese deficiency. He says that a shortage can make the ligaments too stretchy and loose. He prescibed Standard Process Maganese, two tabs in am and pm with meals."

http://www.natmedtalk.com/showthread.php?t=20343

543a65b3004bf5a51974fbdd60d666bb

(4493)

on October 03, 2013
at 05:15 AM

research your manganese dosage. i think you just need to make sure you get the RDA or AI, may be a bit more if you are taking really high zinc (ie. if you are 100mg or more elemental zinc p/d...if at these zinc levels you need to make sure you are not depleting copper as well).

be aware that i think the pyroluria sites generally quote chelated manganese (gluconate/aspartate/citrate) numbers, not elemental, ie. 20mg manganese chelate is about 2mg elemental manganese (may vary between brands & chelates)

0b4326a4949718451a8571b82558dc10

(2349)

on October 03, 2013
at 04:18 AM

My crackling seems to be abnormal & unhealthy..everytime I go for a run I have to stop a couple times in the beginning to squat down and give em a crack. manganese is a recommendation for pyroluria sufferers..maybe it's my missing link. I'm definitely going to try it..i just don't know when I should take it for optimal resulsts...i guess I'm pretty paranoid in this regard

I feel amazing right now!..only red flag is all this cracking haha

543a65b3004bf5a51974fbdd60d666bb

(4493)

on October 03, 2013
at 04:13 AM

got any good ref links you can post up re. the manganese & cracking joints? never heard of that before (or have forgotten if i did).

my joints have cracked all my life, never bothered me, & no pain. i just heard that some peoples joints crack more than others (nitrogen bubbles?) & if there is no pain, then nothing to worry about.

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2 Answers

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32f5749fa6cf7adbeb0b0b031ba82b46

(41757)

on October 03, 2013
at 01:01 PM

I don't think there's a relationship between manganese and magnesium in the body. Break out your periodic table (what do you mean you don't have one?!)

Generally things near each other or in columns (periods) have interactions in biology. Sodium/Potassium (Na/K), Magnesium/Calcium (Mg/Ca), Manganese/Iron (Mn/Fe), Copper/Zinc (Cu/Zn). Since these are metals, they form salts in the body, and have a charge of +1/+2/+3. Generally things with similar charges will compete. Na and K are +1. Mg and Ca are +2. Zn/Cu are +2, Fe is +2/+3. Mn has all sorts of different charges possible. The mineral most likely going to compete with Mn is Fe. If you supplement Mn, don't consume with foods high in Fe.

0b4326a4949718451a8571b82558dc10

(2349)

on October 03, 2013
at 02:15 PM

great information. thanks!

0
718fd304d7abab150730638bf2be5153

(184)

on October 03, 2013
at 08:30 AM

The names are similar, but Mg (magnesium) and Mn (manganese) are totally different. You need about 300mg of magnesium daily, and only 3 mg of manganese.

http://en.wikipedia.org/wiki/Manganese

http://en.wikipedia.org/wiki/Magnesium

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