4

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Can someone explain GALT to me?

Answered on September 12, 2014
Created February 04, 2012 at 8:32 AM

"The largest concentration of lymph tissue in the body surrounds the intestines. Called gut-associated lymphatic tissue, or GALT, this tissue is the guardian of this largest gateway through the body???s defenses, and it actively separates desirable nutrients from undesirable pathogens, and helps mount a defense whenever needed." http://www.womentowomen.com/detoxification/lymphaticsystem.aspx

I've just started researching the lymphatic system and how it relates to weight regulation, particularly the "middle-age spread" phenomenon, but I feel like I'm in a bit over my head in separating the hokum from the real science. Is this what malfunctions in leaky gut syndrome? Is it lymphatic fluid flooding to this area that causes (non-gas)bloat when we eat foods that we are sensitive too?

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on February 05, 2012
at 04:30 AM

The inflammation can access your respiratory system. Eventually, it makes way to your brush border and breaks the barrier allowing a tremendous amount of bacteria and toxins to enter and the Galt is under attack. This means the immune system has to fight a battle on two fronts and is less effective. The more systemic inflammation one has the worse it gets. This is precisely how sepsis cause multi organ system failures and leads to serious M & M.

96bf58d8c6bd492dc5b8ae46203fe247

(37227)

on February 05, 2012
at 12:26 AM

Keep working on them! I totally believe that and suffered 50 years of pain and illness because none of my doctors knew how to help me.

1f8384be58052b6b96f476e475abdc74

(2231)

on February 04, 2012
at 04:59 PM

so when you get sick, like say pnemonia, it is starting in this GALT region...and cancer etc??

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2 Answers

8
Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on February 04, 2012
at 03:30 PM

http://jackkruse.com/where-autoimmunity-cancer-and-disease-collide/ in this blog I go into some detail about the interactions that occur at the GALT. It is a very complex and important thing to understand because most of the inflammation from dietary and environmental mismatches occur here.

In summary, the complex biochemical reactions that occur in the gut appear to be the genesis of where inflammation initially passes in to our body. We need to realize this and avoid eating the things that cause this inflammation. As I have said for close to five years now this means strict avoidance of omega 6???s, all grains and especially wheat of any kind and very limited fructose (fruit or synthetic sources) The gut associated lymphatic tract (GALT) is the first place where our immune systems interact with the outside world. This occurs right below the intestinal brush border and is our first line of defense. It seems to me that evolution has dictated that this is precisely where the battle between health and disease begin in humans and why our immune system is set up ready on that battle front.

1f8384be58052b6b96f476e475abdc74

(2231)

on February 04, 2012
at 04:59 PM

so when you get sick, like say pnemonia, it is starting in this GALT region...and cancer etc??

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on February 05, 2012
at 04:30 AM

The inflammation can access your respiratory system. Eventually, it makes way to your brush border and breaks the barrier allowing a tremendous amount of bacteria and toxins to enter and the Galt is under attack. This means the immune system has to fight a battle on two fronts and is less effective. The more systemic inflammation one has the worse it gets. This is precisely how sepsis cause multi organ system failures and leads to serious M & M.

2
62442eec80b7d248ccfa08f98f736748

on February 05, 2012
at 12:10 AM

no that would be a bit of an overarching generalization... for example, the development of cancers arise from gene mutations that can arise spontaneously or are inherited. there is a complex relationship between environmental factors and genetic predispositions that lead to cancer. the gut is only one way in which pathogens and other environmental factors can affect our bodies. you have to remember that things are absorbed across our skin, our lungs, our nose, open wounds, etc.
while a lot of diseases are associated with gut inflammation from what we ingest, i don't think you can generalize it to all cancers, chronic diseases, etc.

on the other hand...i am trying to convince my med school professors that a lot of chronic disease, especially autoimmune disorders, may start in the gut...

96bf58d8c6bd492dc5b8ae46203fe247

(37227)

on February 05, 2012
at 12:26 AM

Keep working on them! I totally believe that and suffered 50 years of pain and illness because none of my doctors knew how to help me.

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