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High Bilirubin and ALT

Answered on August 19, 2014
Created May 05, 2011 at 5:36 AM

All the numbers on my latest blood test are the same or better than my 2009 pre-Paleo test, except these two:

Bilirubin, total: 1.6
Previously: 1.0
Target: 0.2 - 1.2

ALT (SGPT): 52
Previously: 20
Target: 6 - 40

Does anyone have experience with a change like this, or think it worrisome?

Am I eating more fat than my liver can handle?

I seem to remember some family members with high bilirubin that is supposedly nothing to worry about (possible Gilbert's Syndrome).

I have been taking milk thistle on occasion because it seemed like a good idea, but taking it full strength might be a better idea.

Bb3d1772b28c02da2426e40dfcb533f5

(5381)

on July 30, 2012
at 01:01 PM

I read a rat study that suggests the same about high fat low carb (not that rats are good examples, I am not sure of any human studies). I have mildly elevated bilirubin due to gilberts (which I read is actually good because it lowers ur risk of heart disease), and my ALT is now mildly elevated on low carb paleo...my doctor is mildly concerned. This seems like a good explaination though. Cheers.

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4 Answers

2
Medium avatar

on May 05, 2011
at 05:30 PM

I had an ALT of 48 or so a couple months ago. Paleo eaters will tend to utilize the alanine cycle to a greater extent than the average person from which that range was constructed. If you lower your carbs below what your CNS needs per day, your body will scavenge glucose from any source, one of them being the conversion of alanine to pyruvate and then glucose.

I would wager that increasing carbs to at least 150g would meet all of the glucose needs of your CNS, RBCs etc, and cause a lower ALT as a result. Whether an elevated ALT that coincides with a paleo diet is detrimental to one's health is anyone's guess.

Bb3d1772b28c02da2426e40dfcb533f5

(5381)

on July 30, 2012
at 01:01 PM

I read a rat study that suggests the same about high fat low carb (not that rats are good examples, I am not sure of any human studies). I have mildly elevated bilirubin due to gilberts (which I read is actually good because it lowers ur risk of heart disease), and my ALT is now mildly elevated on low carb paleo...my doctor is mildly concerned. This seems like a good explaination though. Cheers.

1
1bc18852894dad9d6dddfb3dfed49ab3

(341)

on May 05, 2011
at 04:27 PM

I had high bilirubin most of my life making my face to appear yellow. I was low fat during that time. When I switched to high animal fat bilirubin levels went down and my face now has reddish cheeks instead of yellow. My personal opinion is there is something inefficient going on inside the liver, either too many red blood cells are getting broken down or the body can't get rid of bilirubin fast enough. In my case high animal fat appeared to fixed it. My other liver counters were normal before and after.

1
Cbda678b2a6bf0537d8c4ea0ce8aa9ad

(4319)

on May 05, 2011
at 07:09 AM

My two blood tests about 5 or 6 months apart (Sept --> Feb) after starting paleo gave me these results

SGOT (AST) 23 --> 33 SGPT (ALT) 26 --> 45

Bilirubin Total 0.59 --> 1.26

also have the same question as you

I imagine you have googled this. here's one page with some info, but not exactly pertinent to paleo.

http://www.medicinenet.com/liver_blood_tests/article.htm

0
Fd504de9b242f4cd7009db70af5e2121

(558)

on May 05, 2011
at 12:59 PM

hmmm just had bloodwork done for the first time and my bilirubin was 1.4...everything else normal.My Dr,an actual health care practitioner,said no worries

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