I've been eating Paleo since June of '12 and I recently got my newest round of numbers back on my lipid panel. Here are the newest numbers compared with the older numbers.
One set is from 11/2012 and the other set is from 03/2013. Nothing in my diet changed but realize that my body is still morphing I only started eating Paleo in June of '12. since june of '12 ive went from 5' 7 191 lbs down to 143 lbs.
Cholesterol, total 11/12 - 204 mg/dl 03/13 - 221 mg/dl
cholesterol, triglycerides 11/12 - 55 mg/dl 03/13 - 47 mg/dl
cholesterol, HDL 11/12 - 56 mg/dl 03/13 - 60 mg/dl
cholesterol, LDL 11/12 - 137 03/13 - 152
cholesterol, vldl 11/12 - 11 mg/dl
besides my lipid panel it is interesting to note that my free Testosterone went from 10.6 pg/ml in 11/12 to 14.5 pg/ml in 03/13. it is also important to note that my Hemoglobin A1C was slightly high (5.8 H%) but ive read in many articles that this is not a very good marker of sugar in the blood and that many low-carbers tend to have high A1C numbers.
I didn't track my weight according to my lab word days but it went from roughly 157 to 145 from 11/12 to 03/13 if that makes any difference.
I know that the Paleo-centric crowd deemphasizes cholesterol and instead worries more about inflammation but my question is this, what cholesterol markers DO i need to worry about? Obviously my HDL is high, and my tri's are low but what about my ldl? is my high ldl cause for concern? Should I get a VAP test to measure the particle sizes?
Any analysis and commentary is welcome and appreciated.
asked bytrey_5 (0)
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on March 21, 2013
at 12:40 AM
Those cholesterol numbers are good and there is no need to get your particle size tested. It's clear from your trigs, and Trigs / HDL and TC / HDL ratios that your particle size is large. Now, the large particle size doesn't necessarily mean they are completely harmless. They can still be atherogenic but the important thing is inflammation: you don't have much of it. Low trigs => low inflammation. Low Trigs / HDL ==> low bodily inflammation. How are your liver enzymes (ALT, AST)? Are they in the 10s? 20s? No higehr than 25 or so? Then you have low inflammation. You could test with CRP and ESR but usually the liver enzymes and Trigs are sufficient.
Your LDL did go up from about 140 to 152 but is meaningless because you lost a lot of weight and your may lipids may be stabilizing. Plus that margin of increase is just "noise." In the U.S. LDL is usually calculated indirectly.
As for your A1c, 5.8 is an issue and is considered prediabetic. Most low carbers have high FBG, not high overall A1c. Post-prandial numbers are not affected by ketogenic or low-carbing. A1c is not always reliable but is fairly reliable unless you have anemia or RBC/Hb issues. I'd get that retested and make sure it falls below 5.5 or so. If it doesn't, you may have pre-existing blood sugar issues. If you do, low-carbing or avoiding sugar and processed carbs should fix that over the long-term as you haven't crossed the diabetic threshold.
Your free T is now in the midpoint range. If you're doing VLCing, I'd watch my BUN to make sure it doesn't go over 20-25 or so, as it suggests protein overconsumption. More fat, lower protein, and more natural carbs (yams, sweet potatoes, white rice) would be your solution, then.
on March 22, 2013
at 07:08 AM
Without knowing your diet, a number of possible factors could have resulted in higher HbA1C.
If you're in ketosis, ketones and ketone metabolites like methylglyoxal can likely be glycating agents.
Nutrient deficiencies could also be at play; thiamine, vitamin C, magnesium (commonly low in many diets), and zinc are all important in preventing our dealing with glycation. Zinc may be the least likely to be low on a paleo diet, but it's still reasonable you could be coming up short on any of those nutrients.
I don't claim to be an expert on the role of HbA1C as an indicator of disease risk, but if your levels could be indicative of a vitamin and/or mineral inadequacy it seems look a good idea to see if that's what's going on.
on March 22, 2013
at 05:11 AM
Could the eleveated A1C numbers be because im still losing weight?
on March 21, 2013
at 12:19 AM
You didn't provide your ldl numbers but I calculated them to be either 152mg/dl per the Friedewald formula, or more accurately 118mg/dl per the Iranian formula (since your triglycerides are below 100mg/dl). Your numbers appear pretty good as many Paleos tend to have slightly higher ldl's but most likely they are the good "fluffy" type (trigs/hdl). This article is very good at explaining lipid panels.