I would like opinions on this new study and concept please?

Answered on September 12, 2014
Created July 16, 2012 at 2:44 AM

"Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity "

Here's an interesting study - forget about the Glycemic Index, as long as you're eating real veggies and have eliminated grains, sugars and refined oils from your diet, your body will cope with them perfectly - http://www.dovepress.com/articles.php?article_id=10339

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4 Answers


on July 16, 2012
at 12:23 PM

This is not a study, it's a hypothesis. The full text is available as a PDF download and I think it's well worth a read. Here's the author's conclusion:

The increased storage life and convenience of some of our oldest agricultural products may come with a hitherto unrecognized metabolic cost. The foods eaten by hunter-gatherers, non-cereal horticulturalists, and those following a modern Paleolithic or ???primal??? diet are sharply delineated from modern foods by their lower carbohydrate densities. Consumption of exclusively low-density carbohydrates is suggested to produce a less inflammatory GI microbiota, and may explain the apparent absence of overweight and metabolic disease in two of these groups, and the promising early data from the third. This hypothesis may also explain (1) why obesity incidence scales with refined food intake, but has such confusing correlatory patterns with macronutrients; (2) why calorie-controlled diets of Westernized foods require a perpetual fight with homeostatic correction mechanisms; (3) the link between periodontal disease and systemic atherosclerotic disease and obesity; (4) why the benefits of a diet of fruit and vegetables have not been replicated by supplements of the constituent antioxidants, vitamins, minerals, and fiber alongside a Western diet; (5) why low-carbohydrate diets produce ad libitum weight loss, but low-fat diets do not; and (6) the relative resistance of European people to obesity and diabetes from Westernized diets.

We should not settle for the meager improvements attainable from the consensus dietary advice when it is already clear that so much more might be achieved. Our sights should be set high, to see how close we can move levels of industrialized metabolic health toward those enjoyed by non-Westernized populations. While many will resist making dietary changes of such magnitude, official advice must nonetheless point in the correct direction, allowing individuals to make informed decisions.

The social and financial burden of the epidemic of obesity and metabolic syndrome threatens the long-term viability of our health-care systems and perniciously undermines the other benefits of modern civilization, including redirection of scarce financial resources. If this dietary pattern is confirmed to work, practical policy solutions must be sought. Some grain cultivars may be found to produce less inflammation, sprouting techniques may be found to be of benefit, or grain production may be replaced with root-vegetable cultivation where practical. Over time, the interplay between market forces, attainable agricultural yields, and the practicalities of food-distribution networks may allow shifting demand from a newly informed populace to reshape global agribusiness.

A dietary pattern with carbohydrates exclusively from cellular low-density sources may remove the root cause of a range of our most prevalent diseases. The potential savings in health-care costs should be borne in mind, and the hypothesis tested.


on May 25, 2013
at 02:30 PM

It is likely that the overall effects of specific carbohydrate foods on gut flora and systemic inflammation are key to the obesity epedemic. The novel concept of acellular carbohydrates is a new piece to the puzzle, however there are other elements in grains and sugar that contribute to inflammation and gut dysbiosis. Thee elements include fructose content, gluten, lectins, phytates and other antinutrients present in grains, all of which have been proven to promote inflammation and leptin resistance. Basically these foods may be making us fat because they promote inflammation and gut dysbiosis, and not because of their carbohydrate content or GI.


on July 23, 2012
at 03:45 AM

There are tribes doing well eating plenty of wild honey, which is a very concentrated carb, but which has all kinds of immunological and metabolic modifiers in it. I generally would agree with this hypothesis. Whatever the exact detail, it does exclude most of the dietary toxins we were better off without.



on July 16, 2012
at 04:53 AM

I have no technical qualifications, but the abstract from the study jives well with everything I've so far learned about contributors to inflammation, gut flora, and the benefits of various foods (including roots and starches) under ''paleo'' conditions.

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