1

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The leptin reset

Answered on August 19, 2014
Created August 03, 2012 at 4:16 PM

I am sorry for my beginner question, but what is a leptin reset? I am reading about it here, but have no idea what it is, or how it is done. I am guessing, and could be wrong, that it is resetting the bodies leptin levels or production to go in to a healthy range, but I do not know how this is done. also, if someone can help me with some of the glossary terms that to me are a bit new then a year or 2 ago, like BAB, I do not know what this is but am guessing again that it is something to do with breakfast. thank you for your patience.

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on August 11, 2012
at 10:45 AM

Pfff :( now Melissa is gone here that sucks she was by far the coolest paleo ever and had the best answers, never trying to push her own ideas onto others

9d43f6873107e17ca4d1a5055aa7a2ad

on August 09, 2012
at 01:43 AM

I'm not an undergrad...

Da3d4a6835c0f5256b2ef829b3ba3393

on August 04, 2012
at 09:26 PM

LOL@this. Some of these comments are great! "Poor man's Minger" .... "I... generally like Melissa's stuff but she's not an expert.... she is a young lady..." Glad to see PH alive and well!

77877f762c40637911396daa19b53094

(78467)

on August 04, 2012
at 07:02 AM

Melissa is the poor man's Minger, which isn't casting aspersions on her (to the contrary). We won't talk about Minger. My issue is the way sites like this were complicit in the creation of monsters like Kruse who, upon realizing his 15 minutes of fame were almost up, very nearly took a number of good people down with him. Has there been any kind of public accountability for this? Of course not.

A7768b6c6be7f5d6acc76e5efa66464c

on August 04, 2012
at 12:59 AM

@LikesLardinMayo: is your argument that Melissa isn't an expert because she is a young lady and an undergrad? It seems to me the list of "experts" who are not young ladies and are post-doc prepared who are also inept, misguided, and intellectually impoverished seems unlimited.

77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 08:09 PM

I don't follow this stuff and I don't really like Kruse and generally like Melissa's stuff but she's not an expert. As I understand it she is a young lady and an undergrad and not an expert on any subject.

57bef671ea7e05631c9fa56f708bcaa9

(258)

on August 03, 2012
at 07:41 PM

Good summary. One thing to add is it's not entirely Kruse's idea - there are at least 2 other Leptin reset diets out there that came before his, though I think his is the only paleo version.

77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 07:22 PM

My comment stands - this kind of namby-pamby tapdancing around controversial issues and people is what gave us Kruse in the first place. Paleohacks MADE the guy. Courageous people like Dr. Kurt Harris weren't listened to, and we know what happened. Even Kurt doesn't hang around here anymore. Melissa's information may be 'carefully sourced', but she reflects the marked lack of cojones at PH: the perfect hipster "I'm beyond making actual value judgments" pose...

A968087cc1dd66d480749c02e4619ef4

(20436)

on August 03, 2012
at 07:11 PM

@PH - I'm sure this question will stand as it is honest and not trying to bait an argument. Unlike all of your questions.

A968087cc1dd66d480749c02e4619ef4

(20436)

on August 03, 2012
at 07:09 PM

Melissa is Melissa McEwen, a founder of PaleoHacks and author of the blog HuntGatherLove. She is considered an expert on Food Anthropology and her information is carefully sourced. PaleoHipster is a well known troll around here, who apparently gets off by trying to stoke controversy around the likes of Jack Kruse and Jimmy Moore. He has been banned multiple times but keeps coming back. Really just tiresome and pointless.

77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 07:04 PM

Melissa McEwen. A mod here, and one of the people Jack Kruse so publicly implicated in the whole "Krusegate" scandal. I'll not recount the whole thing here, but suffice to say he did her wrong. In a big way. The upshot? Kruse can no longer be discussed here at Paleohacks (per more than one mod) - even critically. It's this kind of limp-wristed response that, in my opinion, creates personages like Kruse in the first place.

Medium avatar

(10611)

on August 03, 2012
at 07:04 PM

She'll find out. And for the record do you wear toe shoes and read poetry in Central Park?

Medium avatar

(10611)

on August 03, 2012
at 06:57 PM

+1 for a succinct summary.

88721bda318289a6e6efb215cd6ba2cd

(78)

on August 03, 2012
at 06:55 PM

scratch that, correction, short of 2 years...

Medium avatar

(10611)

on August 03, 2012
at 06:53 PM

Yet my TG's just hit their lowest level ever - 49 - on a 50% high GI carb diet. Like Dave S says in his comment above, a lot of the leptin reset benefit is created/mitigated by other factors, such as obesity and exercise. If you are insulin resistant it could be very helpful.

A968087cc1dd66d480749c02e4619ef4

(20436)

on August 03, 2012
at 05:05 PM

I should add that it is a program primarily for the obese and morbidly obese who have plenty of leptin but are theorized to be leptin insensitive. Thus, the "reset" of the brain, where the leptin receptors are - primarily in the hypothalamus.

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8 Answers

7
A968087cc1dd66d480749c02e4619ef4

(20436)

on August 03, 2012
at 04:26 PM

It is a theory of Dr. Jack Kruse's that the brain can be rewired to restore leptin sensitivity by following his leptin reset protocol. Probably best to go to his website to read about it. But in a nutshell:

A big protein breakfast within 30 minutes of waking up. 50 grams of protein is typically recommended.

No snacking, whatsoever, period.

3 meals/day, <50g carbs per day following a paleo/primal diet as per Robb Wolf/Mark Sisson

No eating after 7:30 pm

No exercise until leptin sensitivity is restored

Whether or not his theory is correct, many people seem to do well on this plan. I suspect the LC paleo with no snacking are the keys points. Whether it really creates new neural pathways has yet to be demonstrated.

57bef671ea7e05631c9fa56f708bcaa9

(258)

on August 03, 2012
at 07:41 PM

Good summary. One thing to add is it's not entirely Kruse's idea - there are at least 2 other Leptin reset diets out there that came before his, though I think his is the only paleo version.

Medium avatar

(10611)

on August 03, 2012
at 06:57 PM

+1 for a succinct summary.

1
88721bda318289a6e6efb215cd6ba2cd

on August 04, 2012
at 11:44 AM

I am grateful for all the quick responses, but would like to not be a part of argument or tension or drama of any sorts that originally had nothing to do with me in the first place. Thank you for clearing up my lack of knowing, and now I am in the know, I guess, sort of. I personally, as I hope all of use here, deeply enjoy this site, check it and read it often, learn from it, and maybe even help other learn from it as well. I would like to continue doing that, without being a part of confrontation, or instigating it in any way, or potentially being banned for the instigation. Thank you for your answers and allowing me the time to observe something on this site I have never observed before. I wish you all a wonderful weekend. Thanks again.

1
11b7b7ba720a5cd43c74a0ef99a16adb

(3448)

on August 03, 2012
at 06:12 PM

I don't know if the "leptin reset" protocols floating around the internet work or not. I do know that:

1) High levels of triglycerides in the blood produce prevent leptin from crossing the blood-brain barrier which results in leptin insensitivity: (Link-Here).

2) Low fat, high-carb diets result in high levels of triglycerides in the blood (Link-Here).

IMHO, instead of jumping through dietary and lifestyle hoops, the best approach is to simply follow a diet that results in low triglyceride levels (more fat & limited carbs) and the leptin issues will take care of themselves. Paleo, by most people's definition, fits the model to follow.

Medium avatar

(10611)

on August 03, 2012
at 06:53 PM

Yet my TG's just hit their lowest level ever - 49 - on a 50% high GI carb diet. Like Dave S says in his comment above, a lot of the leptin reset benefit is created/mitigated by other factors, such as obesity and exercise. If you are insulin resistant it could be very helpful.

1
Eed7dabde3d61910685845e04605267f

on August 03, 2012
at 04:37 PM

BAB refers to the 'big-arsed breakfast' Jack Kruse says is useful in restoring 'leptin sensitivity'. As Dave S said, it's centred on a large protein breakfast. There's a lot of material about it here - http://jackkruse.com/the-leptin-rx-faqs/ and here http://www.marksdailyapple.com/forum/thread32345.html and a bit here http://www.marksdailyapple.com/dear-mark-leptin-resets-cold-thermogenesis-and-safe-starches/#axzz22VB6RVbx

0
9a5e2da94ad63ea3186dfa494e16a8d1

on August 04, 2012
at 11:54 AM

One aspect of the "leptin reset" protocol is the quantity of protein... 50 grams is quite a lot, a typical egg has about 6g of protein, so 50g is 8 eggs. That is also a huge breakfast, those eggs alone are about 700-750 calories. Not everyone can eat that, and it might cause you to gain weight.

I started to have two fried eggs and a cup of coffee for breakfast every day and noticed a big improvement in energy, mood, and digestion. I feel like my metabolism and digestion changed significantly for the better after a few weeks. I try to stick with a zero-carb breakfast every morning unless I'm working out. In my experience this was pretty effective and didn't require eating 2/3 of a dozen eggs every morning (yuck).

0
88721bda318289a6e6efb215cd6ba2cd

on August 03, 2012
at 06:53 PM

Thank you all for your quick responses. Being Paleo for about roughly 2 years I am guessing my Leptin is on point. the BAB was something I couldn't sort, thank s for the link. One last and final (for now) question, for PaleoHipster, who is Melissa?

A968087cc1dd66d480749c02e4619ef4

(20436)

on August 03, 2012
at 07:11 PM

@PH - I'm sure this question will stand as it is honest and not trying to bait an argument. Unlike all of your questions.

A968087cc1dd66d480749c02e4619ef4

(20436)

on August 03, 2012
at 07:09 PM

Melissa is Melissa McEwen, a founder of PaleoHacks and author of the blog HuntGatherLove. She is considered an expert on Food Anthropology and her information is carefully sourced. PaleoHipster is a well known troll around here, who apparently gets off by trying to stoke controversy around the likes of Jack Kruse and Jimmy Moore. He has been banned multiple times but keeps coming back. Really just tiresome and pointless.

77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 07:04 PM

Melissa McEwen. A mod here, and one of the people Jack Kruse so publicly implicated in the whole "Krusegate" scandal. I'll not recount the whole thing here, but suffice to say he did her wrong. In a big way. The upshot? Kruse can no longer be discussed here at Paleohacks (per more than one mod) - even critically. It's this kind of limp-wristed response that, in my opinion, creates personages like Kruse in the first place.

77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 08:09 PM

I don't follow this stuff and I don't really like Kruse and generally like Melissa's stuff but she's not an expert. As I understand it she is a young lady and an undergrad and not an expert on any subject.

77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 07:22 PM

My comment stands - this kind of namby-pamby tapdancing around controversial issues and people is what gave us Kruse in the first place. Paleohacks MADE the guy. Courageous people like Dr. Kurt Harris weren't listened to, and we know what happened. Even Kurt doesn't hang around here anymore. Melissa's information may be 'carefully sourced', but she reflects the marked lack of cojones at PH: the perfect hipster "I'm beyond making actual value judgments" pose...

A7768b6c6be7f5d6acc76e5efa66464c

on August 04, 2012
at 12:59 AM

@LikesLardinMayo: is your argument that Melissa isn't an expert because she is a young lady and an undergrad? It seems to me the list of "experts" who are not young ladies and are post-doc prepared who are also inept, misguided, and intellectually impoverished seems unlimited.

77877f762c40637911396daa19b53094

(78467)

on August 04, 2012
at 07:02 AM

Melissa is the poor man's Minger, which isn't casting aspersions on her (to the contrary). We won't talk about Minger. My issue is the way sites like this were complicit in the creation of monsters like Kruse who, upon realizing his 15 minutes of fame were almost up, very nearly took a number of good people down with him. Has there been any kind of public accountability for this? Of course not.

Da3d4a6835c0f5256b2ef829b3ba3393

on August 04, 2012
at 09:26 PM

LOL@this. Some of these comments are great! "Poor man's Minger" .... "I... generally like Melissa's stuff but she's not an expert.... she is a young lady..." Glad to see PH alive and well!

9d43f6873107e17ca4d1a5055aa7a2ad

on August 09, 2012
at 01:43 AM

I'm not an undergrad...

B0fe7b5a9a197cd293978150cbd9055f

(8938)

on August 11, 2012
at 10:45 AM

Pfff :( now Melissa is gone here that sucks she was by far the coolest paleo ever and had the best answers, never trying to push her own ideas onto others

0
782d92f4127823bdfb2ddfcbcf961d0e

on August 03, 2012
at 05:21 PM

Don't know much about leptin but see this helpful thread for the acronyms:

http://paleohacks.com/questions/1138/what-are-all-of-these-paleo-related-acronyms-and-terminologies

-3
77877f762c40637911396daa19b53094

(78467)

on August 03, 2012
at 05:25 PM

Don't let Melissa know you posted a Kruse-related question.

Just sayin'.

Medium avatar

(10611)

on August 03, 2012
at 07:04 PM

She'll find out. And for the record do you wear toe shoes and read poetry in Central Park?

88721bda318289a6e6efb215cd6ba2cd

(78)

on August 03, 2012
at 06:55 PM

scratch that, correction, short of 2 years...

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