3

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Fish Oils make Leaky Gut worse?

Answered on August 19, 2014
Created December 21, 2012 at 6:58 PM

Study shows that DHA increases the permeability of tight junctions in the gut. http://www.ncbi.nlm.nih.gov/pubmed/12591548

I know you always hear contradicting things: too much salt, not enough salt, too hard of exercising, not hard enough. But I'm just informing people of the study if you do happen to have leaky gut because my body has never really responded well to fish oils and I'm pretty certain I have leaky gut.

What are your thoughts?

874ff271ca3379984344d5f9f760fec3

(471)

on December 22, 2012
at 10:03 AM

I agree, a bushel of spinach every day gets old andt then the amount of K will be a problem...

3327924660b1e2f8f8fc4ca27fedf2b2

(2919)

on December 22, 2012
at 01:10 AM

"Too much Vitamin A lol" Because there's so many good sources of Vitamin A that we need to concern ourselves wit getting too much, right?

00cd3b6f51530a6832fcda1712edbec3

(2411)

on December 21, 2012
at 11:18 PM

In N. America, you would have spend 20 minutes of every summer day outdoors with your arms and legs completely exposed in order to get enough vitamin D to last you through the other seasons. If you can't or don't want to do this, Vit. D supplements are a cheap and effective way to boost your D levels and maintain them.

A5127d60bca783084f191f38ffa357a6

(687)

on December 21, 2012
at 09:57 PM

Thanks for your thoughts. I'm pretty cut and not that insulin resistant. I hear there is a strong correlation between autoimmune diseases too. I still wonder if it is the AI causing low vit d or Vit d helping exacerbate the AI.

0b73cdbd0cb68aeeda14dafeebb2f828

on December 21, 2012
at 09:48 PM

Cod liver oil is not a good source of Vitamin D or omega 3. Human skin given full body sun exposure creates 10,000~20,000iu of vitamin D3 The amount of vitamin D in a serving of CLO is probably in the region of 270iu. Too little to make any impact on typical vitamin d deficiency status.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on December 21, 2012
at 07:27 PM

Thanks for this. I always wondered why I reacted to cod liver oil.

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4 Answers

1
0b73cdbd0cb68aeeda14dafeebb2f828

on December 21, 2012
at 09:42 PM

It also depends on your Vitamin D3 levels Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier There is quite a lot of research supporting the idea that correcting vitamin D deficiency supports tight junctions.

There is also research showing probiotics are able to reduce zonulin levels. Circulating zonulin levels are a marker of intestinal permeability. It's increased in association with obesity-associated insulin resistance. So reducing obesity/insulin resistance improves tight junctions and so controlling inflammation, (with vitamin D, omega 3, magnesium) will help.

A5127d60bca783084f191f38ffa357a6

(687)

on December 21, 2012
at 09:57 PM

Thanks for your thoughts. I'm pretty cut and not that insulin resistant. I hear there is a strong correlation between autoimmune diseases too. I still wonder if it is the AI causing low vit d or Vit d helping exacerbate the AI.

1
C8586fa2188272d5474d22aa8a500619

on December 21, 2012
at 08:14 PM

Same story with me, I did react to fish oil supplements at the time I had leaky gut.

More confirmation here http://www.ncbi.nlm.nih.gov/pubmed/21775525

On the opposite side, saturated fat is protecting the intestinal barrier: http://www.ncbi.nlm.nih.gov/pubmed/22150547

My grandma used to say: When you are going to drink, eat some lard.(alcohol causes leaky gut) She died in good health at the age of 98.

To me that is another confirmation that supplements are not paleo. Get Vitamin D from sun and omega 3 from unprocessed fish.

00cd3b6f51530a6832fcda1712edbec3

(2411)

on December 21, 2012
at 11:18 PM

In N. America, you would have spend 20 minutes of every summer day outdoors with your arms and legs completely exposed in order to get enough vitamin D to last you through the other seasons. If you can't or don't want to do this, Vit. D supplements are a cheap and effective way to boost your D levels and maintain them.

1
A2c38be4c54c91a15071f82f14cac0b3

(12682)

on December 21, 2012
at 07:22 PM

Well, this was an ex vivo study so the extrapolation to real life is suspect, but I do think the basic idea will be true. When you have an imbalanced ratio of O3 to O6 in favor of omega-3 you lower the production of omega-6 derived eicosanoids like prostaglandins.

Omega-6 gets bashed a lot because it can be turned into "inflammatory" compounds, but O6 derived prostaglandins are important in regulating intestinal tight junctions and which helps keep our guts from being leaky.

So yeah, the ratio is still the important thing. If you have suspected leaky gut issues I think it may be advisable to avoid that touted 1:1 ratio of omega 3 to 6 and if taking fish oils push you that far or farther they may have negative effects.

-1
383127951e2e17f23b584cd3842bb796

(835)

on December 21, 2012
at 08:30 PM

stay away from cod liver oil. it contains way too much vitamin a

3327924660b1e2f8f8fc4ca27fedf2b2

(2919)

on December 22, 2012
at 01:10 AM

"Too much Vitamin A lol" Because there's so many good sources of Vitamin A that we need to concern ourselves wit getting too much, right?

0b73cdbd0cb68aeeda14dafeebb2f828

on December 21, 2012
at 09:48 PM

Cod liver oil is not a good source of Vitamin D or omega 3. Human skin given full body sun exposure creates 10,000~20,000iu of vitamin D3 The amount of vitamin D in a serving of CLO is probably in the region of 270iu. Too little to make any impact on typical vitamin d deficiency status.

874ff271ca3379984344d5f9f760fec3

(471)

on December 22, 2012
at 10:03 AM

I agree, a bushel of spinach every day gets old andt then the amount of K will be a problem...

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