1

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Very high ketone levels?

Asked on September 18, 2014
Created July 14, 2014 at 6:03 PM

So I've been trying to do a ketogenic diet for about five or six weeks now and I'm still feeling like crap. Assuming that my ketone levels were not up to nutritional ketosis levels, I started testing my ketone levels and they've been consistently higher than the recommended range that I've seen online. They typically range around 5 mmol/L with the highest I've tested at 7.4 mmol/L. So my ketone levels are very high, but yet I still have the mental fogginess, fatigue etc associated with the adaptation phase. I've never seen anyone doing nutritional ketosis testing at these levels, any idea what is going on?

96440612cf0fcf366bf5ad8f776fca84

(19463)

on July 16, 2014
at 10:06 AM

One thing that helps to eat a lot of extra meat, this gets converted to glucose via gluconeogenesis. That mechanism might be lacking in some folks, so it's good to exercise it once in a while; you don't want to over do it as it'll produce a lot of ammonia, which needs to be disposed of, but it can help.

96440612cf0fcf366bf5ad8f776fca84

(19463)

on July 16, 2014
at 10:05 AM

You could have also added in extra meat for gluconeogenesis. But yeah, VLC or ZC does cause sleep issues via cortisol signaling.

Be803dcde63e3cf5e21cc121097b8158

(529)

on July 16, 2014
at 02:01 AM

Just a thought, but drinking more water than you need will dilute your electrolytes, and your sodium needs are already quite high on a VLC diet. So maybe try salting the gallons of water that you drink.

C270e06a9e5507bb1c4c409097dda6c9

(5)

on July 15, 2014
at 12:58 AM

Blood sugar typically hovers around 70 or so using my precision xtra meter. Not dehydrated, I drink a huge amount of water at least a gallon sometimes upwards of 2 gallons a day. I supplement with plenty of salt, I supplement with potassium as well but I might not be taking in enough.

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5 Answers

0
Be157308a0438e382b88d9db4c12ab30

on July 16, 2014
at 06:40 PM

If you need a boost just drink some black tea or coffee for caffeine, this promotes gluconeogenesis without need for increased glucose or protein intake so you basically get calorie-free energy due to the fact that caffeine competitively blocks the adenosine receptors in the brain. So you could continue to enjoy ketosis without being tired. You could also go via an alternate route and consume more dark chocolate (90%+) or cocoa powder which contains a hefty amount of theobromine (my preference), which has essentially the same effects as caffeine with a few differences. On the plus side, caffeine and theobromine are anti-inflammatory as they inhibit tumor necrosis factor alpha (TNF http://en.wikipedia.org/wiki/Tumor_necrosis_factor_alpha). Enjoy!

0
96440612cf0fcf366bf5ad8f776fca84

(19463)

on July 16, 2014
at 10:07 AM

Your mitochondria aren't (yet) used to burning ketones, the fuel source is there, your liver is producing them, and your fat cells are releasing fat, but your cells do not yet recognize is at source of food because they've been too long without it.

It's also possible that you're not producing enough glucose via gluconeogenesis, but the fact that your ketones are very high means that they're not being used.

You could try cycling in and out of ketosis so that you have periods of both higher glucose and no glucose to see if it will help.

You can try an HIIT routine and some weight lifting - muscle cells can grow mitochondria based on how much they're being used, hopefully the new ones will be better at consuming ketones. You can try working out fasted as well.

It might help to supplement with PQQ, or consume food sources that are high in it such as kiwi, or parsley.

0
Medium avatar

on July 15, 2014
at 08:59 PM

I always feel fantastic in deeeeep ketosis but sleep suffered tremendously, did the tbsp of honey and that fixed everything even though I dont get the deep ketone levels given the 16g of sugar :/

96440612cf0fcf366bf5ad8f776fca84

(19463)

on July 16, 2014
at 10:06 AM

One thing that helps to eat a lot of extra meat, this gets converted to glucose via gluconeogenesis. That mechanism might be lacking in some folks, so it's good to exercise it once in a while; you don't want to over do it as it'll produce a lot of ammonia, which needs to be disposed of, but it can help.

0
3ce6a0d24be025e2f2af534545bdd1d7

(26217)

on July 15, 2014
at 01:30 AM

ketosis isn't for everyone I spent a little over two months in constant ketosis when I experimented with it (consistently below 2.5 mmol/L usually below 5). I felt tired, anxious, and had terrible sleep. Added carbs back in and felt great.

96440612cf0fcf366bf5ad8f776fca84

(19463)

on July 16, 2014
at 10:05 AM

You could have also added in extra meat for gluconeogenesis. But yeah, VLC or ZC does cause sleep issues via cortisol signaling.

0
3491e51730101b18724dc57c86601173

(8395)

on July 14, 2014
at 10:37 PM

What's your blood sugar doing?

And what method are you using to measure ketones?

Are you dehydrated? Drinking fluids is not enough, you need a good balance of potassium and sodium, too.

C270e06a9e5507bb1c4c409097dda6c9

(5)

on July 15, 2014
at 12:58 AM

Blood sugar typically hovers around 70 or so using my precision xtra meter. Not dehydrated, I drink a huge amount of water at least a gallon sometimes upwards of 2 gallons a day. I supplement with plenty of salt, I supplement with potassium as well but I might not be taking in enough.

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