I generally subscribe to the Kurt Harris doctrine that supplements are a poor substitute for simply eating natural foods in accordance with paleolithic principles.
However, I recently bought some L-lysine and leucine powders and am experimenting with them.
As many of you know, our bodies can break down most proteins into glucose, so a high protein diet (as opposed to a high fat, low carb diet) will tend to have only muted ketogenic effects. L-lysine and leucine are the exceptions; they are the only exclusively ketogenic amino acids.
And of course coconut oil and heavy cream, especially in the absence of carbs, induce ketosis.
So I occasionally make myself a "ketogenic cocktail" with all four of the ingredients: L-lysine, leucine, heavy cream, and coconut oil. I typically mix a few drops of vanilla extract and sometimes some unsweetened cocoa powder. Since I rarely eat anything sweet, this mixture actually tastes like dessert to me.
I was wondering if anyone else has experimented with mixing these ingredients before. Have you noticed any significant differences in how you feel or look? Have you measured your level of ketosis to see whether consuming the "ketogenic cocktail" has any significant impact?
asked byRoger_L__Cauvin (35)
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on June 30, 2012
at 04:37 PM
I've been tempted to try a similar thing before, but have not.
Because leucine may be able to stimulate protein synthesis a bit in the absence of some other amino acids, theoretically it could lower overall protein requirements for a low-cal diet (I stole this from Paul Jaminet).
Like you said, leucine and lysine are ketogenic. And gelatin has the latter in spades, so I figured eating more gelatin and supplementing with leucine around workouts during a low-cal keto diet may be something to try.
But...no. I wussed out. Why? I couldn't get the math right. If you need X grams of essential amino acids, and Y grams of glucose for your nervous system, at least until ketosis kicks in, I couldn't figure out if the benefits of burning an extra amount of calories from deep ketosis before a weekly (carb up / mini potential leptin resset) would be worth it and not jeapordize muscle retention. Does that make sense or am I just tired and writing poorly?
on January 24, 2014
at 11:00 PM
I'm not working on enough cylinders do do the math either, but adding the other two branch chain amino acids to the mix (isoleucine and valine) might prevent the muscle catabolism you're concerned about. Also, word on the street is that the CNS might preferentially burn ketones like betahydroxybutyric acid, so you can might not need daily glucose. Sorry I have no references to share. This word came from the literal street.
Anyway - if you do try let me know how it goes.