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Optimal fasting insulin level?

Answered on August 19, 2014
Created June 05, 2012 at 5:17 AM

What is ideal/optimal for a fasting blood draw for Insulin?

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 21, 2012
at 08:13 PM

Thank you Beth (and sorry it took me so long to say that!)

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7dc950fc76a046048e683d2a27dced37

on June 05, 2012
at 01:21 PM

Stephan Guyenet wrote a post about this a few years back. Relevant section:

Elevated fasting insulin is a hallmark of the metabolic syndrome, the quintessential modern metabolic disorder that affects 24% of Americans (NHANES III). Dr. Lamarche and colleagues found that having an insulin level of 13 uIU/mL in Canada correlated with an 8-fold higher heart attack risk than a level of 9.3 uIU/mL (1; thanks to NephroPal for the reference). So right away, we can put our upper limit at 9.3 uIU/mL. The average insulin level in the U.S., according to the NHANES III survey, is 8.8 uIU/mL for men and 8.4 for women (2). Given the degree of metabolic dysfunction in this country, I think it's safe to say that the ideal level of fasting insulin is probably below 8.4 uIU/mL as well.

...

So what's the ideal fasting insulin level? My current feeling is that we can consider anything between 2 and 6 uIU/mL within our evolutionary template, although the lower half of that range may be preferable.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 21, 2012
at 08:13 PM

Thank you Beth (and sorry it took me so long to say that!)

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