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insulin precurors etc

Answered on August 19, 2014
Created January 23, 2012 at 8:23 PM

i'm probably not going to word this right or overgeneralizing but whatever,

what are the precursors (hormones, minerals etc) that MAJORLY affect insulin, especially hyperinsulinemia

so far i have

high cortisol
low magnesium 
sex hormones--  high testosterone (in women), low SHBG.........

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64433a05384cd9717c1aa6bf7e98b661

(15236)

on January 23, 2012
at 10:45 PM

Having too much leptin!

Ceddia RB, William WN, Jr., Lima FB & Curi R. 1998. Leptin inhibits insulin-stimulated incorporation of glucose into lipids and stimulates glucose decarboxylation in isolated rat adipocytes. J Endocrinol 158(3):R7-9.

Kieffer TJ, Heller RS, Leech CA, Holz GG & Habener JF. 1997. Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells. Diabetes 46(6):1087-1093.

Lam NT, Cheung AT, Riedel MJ, Light PE, Cheeseman CI & Kieffer TJ. 2004. Leptin reduces glucose transport and cellular ATP levels in INS-1 beta-cells. J Mol Endocrinol 32(2):415-424.

Walder K, Filippis A, Clark S, Zimmet P & Collier GR. 1997. Leptin inhibits insulin binding in isolated rat adipocytes. J Endocrinol 155(3):R5-7.

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