1

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Interleukin 6 or CRP?

Answered on August 19, 2014
Created March 06, 2013 at 6:23 PM

If you were going to get a blood test to measure inflammation would you choose Interleukin 6 or CRP and why?

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on March 08, 2013
at 03:12 PM

Not specifically for inflammation markers. I had a bunch of tests done with Life Extension to get information and a baseline (haven't had comprehensive blood tests like this before). Hormones, Vitamin D and B12 levels, O3 vs O6, that sort of thing. There's "feeling", then there's "knowing". If I can swing it, I'm going to have the same tests done later this year to see where the numbers went after a year's changes.

06bf7b92d77f1ac1d8e3dc9d539d8254

(1649)

on March 07, 2013
at 05:53 PM

Good to know! Did you do other bloodwork at the time? Like was there something indicated on a standard blood panel that lead you to explore inflammation markers?

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2 Answers

1
800e726cb5dff569fd8edf604c3e2793

on March 21, 2013
at 03:19 PM

Generally speaking, you want both and more.

If you want to gauge the state of inflammation in your body (as opposed to get a number and trust in it), you'd do better to get as many data points as you can -- measure your CRP, get a cytokine panel, check the rheumatoid factor, don't forget to look at your white blood cells count, etc.

The more data you have, the better estimate of what's happening with your body you'll get.

1
5e36f73c3f95eb4ea13a009f4936449f

(8280)

on March 07, 2013
at 07:53 AM

I'd say go with CRP. In checking some of the research, it indicated that IL6 leads to CRP, and that IL6 was not really as consistent as CRP across the genders/smokers. Not sure if there just hasn't been as much research done with IL6 as there has been with IL6 yet or not.

CRP is substantially cheaper (something like $50 vs $400 when I had them done last year). IL6 was still saying it was research only (so not as much a standard out there like CRP is). Don't know whether it is now a standard type of test or not, and I don't know that it would give useful information without multiple tests (because you really need to see how the numbers go over time vs a single snapshot).

In terms of comparing, I had a CRP of 1.92, on a range of 0.00-3.00, where 1.00-3.00 is average and over 3 is high. I had a IL6 of 2.2 on a range of 0.0-15.5 (no listing as to averages/high like CRP). Numbers are kind of hard to extrapolate to CRP though without more tests. I had the money to splurge at the time, and I wanted to get a baseline on a lot of info, so I added in IL6 a couple weeks after I did CRP (so they weren't at the same time either).

06bf7b92d77f1ac1d8e3dc9d539d8254

(1649)

on March 07, 2013
at 05:53 PM

Good to know! Did you do other bloodwork at the time? Like was there something indicated on a standard blood panel that lead you to explore inflammation markers?

5e36f73c3f95eb4ea13a009f4936449f

(8280)

on March 08, 2013
at 03:12 PM

Not specifically for inflammation markers. I had a bunch of tests done with Life Extension to get information and a baseline (haven't had comprehensive blood tests like this before). Hormones, Vitamin D and B12 levels, O3 vs O6, that sort of thing. There's "feeling", then there's "knowing". If I can swing it, I'm going to have the same tests done later this year to see where the numbers went after a year's changes.

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