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How does one minimize IGF-1?

Answered on August 19, 2014
Created August 25, 2011 at 6:14 AM

How does one minimize IGF-1?

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on August 26, 2011
at 07:16 AM

I am cooking for a friend with cancer and I am thinking that minimizing the IGF-1 impact and insulin response of the meals might help...

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on August 26, 2011
at 07:15 AM

I am cooking for a friend with cancer and I am thinking that minimizing the IGF-1 impact and insulin response of the meals might help...

8c2d9e2db306fbe72d857fcea4ee8778

(100)

on August 25, 2011
at 07:15 AM

Have not seen the lecture, took a look at slides; looks like John McDougall redux. Although I believe Denise Minger's site has some stuff on dairy and disease, and it's all in dairy's favor, LET'S ASSUME foods which increase IGF-1 (or action of) have some bad effects, such as promoting tumor growth, at least under some conditions. Have you weighed those possible bad effects against the good ones?

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5 Answers

3
8c2d9e2db306fbe72d857fcea4ee8778

on August 25, 2011
at 06:43 AM

Why would you wish to?

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on August 26, 2011
at 07:15 AM

I am cooking for a friend with cancer and I am thinking that minimizing the IGF-1 impact and insulin response of the meals might help...

2
F4d04667059bc682540fdfd8b40f13a7

on August 25, 2011
at 06:49 AM

Have you seen Pedro Bastos fantastic AHS lecture? IGF-1 came up lots as I recall... http://www.slideshare.net/ancestralhealth/ahs-slidespedro-bastos-8827808

*edited to say - check out the slides from page 50

8c2d9e2db306fbe72d857fcea4ee8778

(100)

on August 25, 2011
at 07:15 AM

Have not seen the lecture, took a look at slides; looks like John McDougall redux. Although I believe Denise Minger's site has some stuff on dairy and disease, and it's all in dairy's favor, LET'S ASSUME foods which increase IGF-1 (or action of) have some bad effects, such as promoting tumor growth, at least under some conditions. Have you weighed those possible bad effects against the good ones?

1
24df4e0d0e7ce98963d4641fae1a60e5

on August 25, 2011
at 02:14 PM

I'm with H.T. I'm not sure why you would want to.
I blogged on a study demonstrating increased protein content in the diet increasing IGF-1 and improving glucose homeostasis: http://carbsanity.blogspot.com/2011/06/protein-insulin-like-growth-factor-1.html

1a98a40ba8ffdc5aa28d1324d01c6c9f

(20378)

on August 26, 2011
at 07:16 AM

I am cooking for a friend with cancer and I am thinking that minimizing the IGF-1 impact and insulin response of the meals might help...

1
5ccb98f6ae42ce87e206cf3f6a86039f

(11581)

on August 25, 2011
at 10:23 AM

Protein restriction seems to work, at least in combination with a calorie restricted diet. "Reducing protein intake from an average of 1.67 g kg(-1) of body weight per day to 0.95 g kg(-1) of body weight per day for 3 weeks in six volunteers practicing CR [calorie restriction] resulted in a reduction in serum IGF-1 from 194 ng mL(-1) to 152 ng mL(-1)." http://www.ncbi.nlm.nih.gov/pubmed/18843793

1
2c8c421cf0e0c462654c7dc37f8b9711

(2729)

on August 25, 2011
at 07:33 AM

When Mat LaLonde was on Robb Wolf's podcast (during the AHS), he mentioned that IGF-1 in dairy is destroyed by fermentation.

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