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Iron overload and Anemia, with impaired Kidney function, Hypothyroid - Labs Values Added

Answered on August 19, 2014
Created June 24, 2011 at 7:35 PM

Does anyone have any experience with Iron overload with Anemia. Further to that, it appears these issues have lead to impaired kidney function and hypothyroid.

I understand the body doesn't eliminate excess Iron except through blood loss. It also has a built in mechanism to prevent too much accumulation of Iron, mine mechanism seems to be broken - Hemochromatosis. Seems like a the simple fix would be to donate blood until my levels were back down to normal. Due to the Anemia, this doesn't appear to be an option.

I'm trying to put this all together to see which front to attack first. Since Iron is pro-inflammatory, I'm guessing that's what needs to be addressed first, which would improve the kidney function, which could assist with Anemia, and then the thyroid could come back to normal (as it's likely responding to inflammation)?

Anyone have input? I have lab values that I can add to this when I have access.

Blood Chemistry Report

Marker Value

  1. Glucose 96
  2. Hemoglobin A1c 5.1
  3. Uric Acid 6.2
  4. BUN 21
  5. Creatinine 1.40
  6. Sodium 138
  7. Potassium 4.2
  8. Chloride 101
  9. C02 24
  10. Calcium 9.5
  11. Phosphorus 4.7
  12. Magnesium 2.1
  13. Protein, total 6.2
  14. Albumin 4.3
  15. Globulin 1.9
  16. A/G ratio 2.3
  17. Bilirubin 0.6
  18. Alkaline Phosphate 54
  19. LDH 141
  20. AST 30
  21. ALT 20
  22. GGT 16
  23. TIBC 222
  24. UIBC 75
  25. Iron 147
  26. Iron saturation 66
  27. Ferritin 215
  28. Cholesterol, total 280
  29. Triglycerides 24
  30. HDL 115
  31. LDL 160
  32. Triglycerides / HDL Ratio 0.21
  33. TSH 1.80
  34. T4, total 6.5
  35. T3 Uptake 37
  36. T3, Total 61
  37. Vitamin D, 25-hydroxy 53
  38. WBC 3.5
  39. RBC 3.63
  40. Hemoglobin 12.2
  41. Hematocrit 35.4
  42. MCV 98
  43. MCH 33.6
  44. MCHC 34.5
  45. RDW 13.4
  46. Platelets 164
  47. Neutrophils 48
  48. Lymphocytes 37
  49. Monocytes 11
  50. Eosinophils 3
  51. Basophils 1
  52. B-12 1213

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on February 05, 2012
at 06:10 PM

Thanks, Eric. I have had my testosterone checked and it was fairly low, which sounds similar to your situation.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on June 24, 2011
at 10:55 PM

Thanks for the link

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on June 24, 2011
at 09:54 PM

My problem is absorbing too much Iron, and that was confirmed by my dr.

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5 Answers

1
046e8437a1df34809119896d2a47926a

on February 04, 2012
at 10:48 PM

I have hereditary hemochromatosis (C282y+/+), the genetic test came back last week, but the high iron levels were discovered in a blood test one month ago. I was also on the slightly anemic side, RBC just below 4.0 and hemoglobin around 12. I had read in books on hemochromatosis that 12 was the threshhold for hemoglobin for tolerating the phlebotomy's (giving one unit of blood/week until iron levels are in check). My hematologist told me 10-10.5 was a safe level for giving blood, so they will check each week before my phlebotomy.

My testosterone levels were extremely low because the high iron levels had shut down my pituitary gland. Testosterone deficiency can cause anemia because the hormone helps stimulate kidneys and bone marrow to produce erythropoietin (this hormone stimulates red blood cell production) and stem cells. Hopefully with testosterone therapy during the period of my phlebotomys my red blood cell count will go up and I will be able to tolerate the treatment. Check with your doctor, but you should be able to tolerate the phlebotomy, and get you Testosterone checked as well. The iron overload I believe can effect your thyroid gland as well.

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on February 05, 2012
at 06:10 PM

Thanks, Eric. I have had my testosterone checked and it was fairly low, which sounds similar to your situation.

1
13c5a9f1678d75b93f269cdcf69f14d5

(2339)

on June 24, 2011
at 08:35 PM

Check out the Off the Grid blog; she has posts on these topics

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on June 24, 2011
at 10:55 PM

Thanks for the link

0
A0375c20e2afd578f733bc311a9fc739

(0)

on December 27, 2012
at 07:25 AM

EDTA. Try Medicardium. May help with both high iron and kidney function.

0
2cdcd4f9ea457f885f056dcd829b4af8

on December 26, 2012
at 04:41 PM

Hi, I have experience with chronic iron overload with anemia plus renal impairment and hypothyroidism.   Anaemia (error) Replaced Beta - thalassemia (mistakenly Treatment Antianemika) plus H63D hemochromatosis.   Corollary - iron overload-secondary hemochromatosis. This is a rare combination of the Sephardim. I found this information on the Internet translated via Google

0
1f8384be58052b6b96f476e475abdc74

(2231)

on June 24, 2011
at 09:24 PM

some people dont absorb iron. go to the doctor. it is very dangerous to OD on iron and not absorb it

50637dfd7dc7a7e811d82283f4f5fd10

(5838)

on June 24, 2011
at 09:54 PM

My problem is absorbing too much Iron, and that was confirmed by my dr.

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