6

votes

Anyone Have Reactive Hypoglycemia?

Commented on October 07, 2015
Created May 08, 2013 at 8:17 PM

I had been plagued by this for about the last 20 years. Was able to manage it with certain diet compositions, but I knew there was some nutrient missing. Tried magnesium, zinc, chromium etc. with no perceptible difference. I then decided to try taking a biotin supplement (500mcg d-biotin once a day), and lo and behold, it completely corrected it for me. I don't know if it's because my gut bacteria aren't producing it or I have some failure of biotinidase that is causing it to be insufficiently recycled, but whatever the reason, this supplement has completely corrected it.

I've seen some studies where it's used to help diabetics, so I'd say that if you're having trouble managing your blood glucose in some way or another, you might want to give it a try.

Interestingly, I used to be unable to take vitamin k-2 because even 45mcg for a few days would cause a day of blood sugar episodes until my levels dropped again. I can now take 360mcg a day with zero issues. They're both involved with carboxylation, but I corresponded with a K2 researcher and he wasn't sure why that would occur but said they don't interact at all. No idea, but I'm psyched about being able to carboxylate osteocalcin and MGP.

Lastly, this supplement is most often used by women trying to grow healthier hair and nails, and I definitely noticed that what hair I have grows faster, as do my fingernails. My skin is also much less dry, since it's involved in the processing of EFAs and other fatty acids.

It comes in large doses like 5 and 10mg, but I don't really see the point of taking that much, though I don't know if it'd actually be harmful. I've seen some reports of people getting acne from it, but I think that's simply the result of them finally having adequate sebum production, and because they're deficient in vitamin A and/or zinc, it exacerbates the situation. I noticed no such reaction.

857059a6b013e8104200e450963c98d5

on October 07, 2015
at 11:48 PM

How long until the biotin worked for hypoglycemia? thank you!

618fc5298c4a96b817c4918c795a875f

(1217)

on May 23, 2013
at 05:12 AM

Thank YOU for this - you made something that was previously murky very clear!!! Appreciated!

67ad8220077cac36946d42a17f4549ee

on May 23, 2013
at 04:14 AM

Here's some good info on Biotin and Hypoglycemia: http://www.livestrong.com/article/544874-biotin-and-hypoglycemia/

89fa2da4805b0b4e54b77a5a20a2e206

(2097)

on May 09, 2013
at 11:07 PM

@Travis-Glad to see you back and in good form :)

Cb9a270955e2c277a02c4a4b5dad10b5

(10979)

on May 09, 2013
at 06:29 PM

Thorne is a vitamin manufacturer. They make a vitamin k2 product, specifically the mk4 version of k2, not the mk7 version which is naturally found in vegetarian fermented products. @Travis, I just started incorporating a nice mayonaise with my meals, turning out to be quite the cook, so I'm getting some raw egg yolks in me (o3 rich Christopher eggs). That's awesome that you noticed that synergy, I'll keep a note of that, and like I said, I want to see more of your pretty face on these boards (besides we need some more super mods to tame this Bill Bailey spammer kid).

1edb06ded9ccf098a4517ca4a7a34ebc

(14952)

on May 09, 2013
at 02:15 PM

@ Travis- This is interesting. It may be worth also looking into r-alpha lipoic acid. I don't have hypoglycemia but I use it with post workout carbs to facilitate glycogen replenishment without the need for extra insulin. I recommend you look into it if you haven't already.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on May 09, 2013
at 09:54 AM

Travis - once you treat the cause, your body will produce biotin on its own. By the way, I did not understand anything about thrones k2-mk4. Could you spell it out for me please?

Medium avatar

(39821)

on May 09, 2013
at 05:20 AM

VB: My dark circles are fading, actually, due to the biotin or k2. I've seen people claim that either one made them go away. Stephen: egg yolks are probably the best food source. I think my hypoglycemia was most under control pre-supplementation when I was eating about 4 a day. I wonder though if the pastured hens are fed a biotin supplement or if battery eggs are better in that regard.

Medium avatar

(39821)

on May 09, 2013
at 05:17 AM

One thing I noticed was that I could eat natto every day but not take the equivalent amount of mk-7. I only recently discovered that natto is a fairly good source of biotin (that I think is added to the culture since the bacteria require it), but I don't think it's a sufficient amount since heavy natto consumers are more prone to diabetes than those who don't eat it.

Cb9a270955e2c277a02c4a4b5dad10b5

(10979)

on May 09, 2013
at 03:18 AM

So are you saying that my o3 biotin rich raw egg yolks w/o the whites coupled with my thrones k2-mk4 are going to work synergistically to pimp out my blood glucose? If so then plus the f' one, thanks for sharing Travis! I want to see more of you on here now!

Cb9a270955e2c277a02c4a4b5dad10b5

(10979)

on May 09, 2013
at 03:17 AM

So are you saying that my o3 biotin rich egg yolks coupled with my thrones k2-mk4 are going to work together to pimp out my blood glucose? If so, + the f'k 1, thanks for sharing!

Cb9a270955e2c277a02c4a4b5dad10b5

(10979)

on May 09, 2013
at 03:05 AM

Biotin is found abundantly in raw egg yolks right? And acidic in whites? And avid in competes with biotin?

63075669c2ec8cb6dab906c334c9b911

(112)

on May 08, 2013
at 09:11 PM

Hmm, I may come back to this if I'm unable to solve my issues with my diet which I am presently experimenting with.

048dd52752c45129c1212bfffb37ca72

(3150)

on May 08, 2013
at 08:50 PM

+1 for sharing this useful info. When I was a vegetarian and eating grains and also a lot into fruit and doing my own smoothies I had some episodies of reactive hypoglycemia just after the smoothies and/or grain breads, specially for breakfast. But I've gone rid of them long ago since I lowered my fruit intake and got rid of grains. Well, not really sure if I got rid if I don't actually eat that way hehe.

F5a0ddffcf9ef5beca864050f090a790

(15515)

on May 08, 2013
at 08:37 PM

I know nothing about hypoglycemia, but I used to be biotin-deficient. I had to take additional vitamins - GNC Hair, Skin and Nails. As soon as I got rid of SIBO (after the first round of metronidazole) - my hair got bushy and my nails got so much harder! And now, after getting rid of my giardiasis my dark circles are going away as well! Not sure if you want to consider it, but maybe it is worth a try to find the reason behind your body not producing/absorbing important nutrients?

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2 Answers

1
1edb06ded9ccf098a4517ca4a7a34ebc

on May 11, 2013
at 02:48 PM

(I'm going to answer just because this is too big for a comment)

First off, let me get out of the way that this is a very interesting and potentially useful hack. Thanks for sharing it. Second off, let me add the disclaimer that I do not have reactive hypoglycemia personally, and that I am not a doctor (as i'm sure you are aware) so take what I say with a grain of salt (which you should do anyways).

From what I understand about reactive hypoglycemia, is that it occurs when you ingest carbohydrate (or protein without sufficient carbohydrate to balance the insulin rush) and your pancreas overshoots the amount of insulin necessary to transport the glucose to your cells. Then you rebound and end up with low blood sugar, despite having ingested carbs. So, what this means is, if you can circumvent the insulin-carb-transport pathway, and instead take advantage of "non-insulin-dependent glucose-uptake," then your problem may be treated.

One way to take advantage of NIDGC is to stimulate your muscle fibers, and particularly your type II (fast twitch) muscle fibers, and, to a somewhat lesser extent, your type I (slow twitch) fibers as well. These will have the affect of increasing your muscular insulin sensitivity, and increasing insulin sensitivity means requiring LESS insulin to get the same job done (transport x amount of carbs to your cells). So, I invite you to consider the therapeutic efficacy of HIIT/strength/weight/bodyweight training.

Another way to take advantage of NIDGC is to eat your carbs in the beloved "post workout window." This is the diminishing window of time when your muscle cells are most insulin sensitive, and it begins the moment you stop working out and declines there after (although remains elevated among baseline in comparison to "average" people). So, I would suggest that if you do take up my suggestion on point one, to try to consume the majority of your carbs in/around your workout window. Generally as close to finishing weight training as possible. A small pre workout carb meal is fine and perhaps needed, and then 2 larger carb meals post workout should do the trick (one immediately...like fruit) and then another 1-3 hours later (like meat/starch).

Finally, the third way is the use of alpha lipoic acid or r-alpha lipoic acid. This is a "universal antixidant" (both water and fat soluble) and is crucial for blood glucose transport. WHat this nutrient does is fascilitate glucose transport without the need for additional insulin, so it affectively lowers your insulin load. I have been taking this for the past 7 years with my post workout meal, and I do feel that it aids in glycogen replenishment (however, there is the risk for bias and placebo). However, don't take my word for it, I suggest you read up on r-ala and experiment with it yourself.

I really do think all of these will work synergistically to amplify the therapeutic affect, but of course one is better than none, in my opinion. I would invite you to at least consider these options as well.

Thanks for the excellent hack, as usual.

618fc5298c4a96b817c4918c795a875f

(1217)

on May 23, 2013
at 05:12 AM

Thank YOU for this - you made something that was previously murky very clear!!! Appreciated!

0
67ad8220077cac36946d42a17f4549ee

on May 23, 2013
at 04:10 AM

I have reactive hypoglycemia, yes. Unforunately. I am currently working on getting off of Metformin ER, as I feel it may be contributing to the hypoglycemic episodes. I am on week 3 of eating Paleo. Hoping to correct it with my diet, so the info you've given is great! Any other feedback would be awesome.

67ad8220077cac36946d42a17f4549ee

on May 23, 2013
at 04:14 AM

Here's some good info on Biotin and Hypoglycemia: http://www.livestrong.com/article/544874-biotin-and-hypoglycemia/

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