4

votes

Have I fixed my Leptin issues?

Answered on August 19, 2014
Created May 26, 2012 at 5:16 PM

I guess this is part Catharsis but there is a question in here, I promise. For as long as I can remember have been the guy that did not push himself away from the dinner table until my belly felt like it was going to bust. I simply did not feel full until I was overly full and by then it was too late. There were actual instances of my brain telling me to stop eating but my belly told me to continue and the belly won every time. I imagined there was a physical trigger that told us when we were full, a set of nerves or sensors in the abdomen just outside the stomach that told you to stop eating as your stomach filled with food and pressed against them. I assumed that for whatever reason mine were further away and so I didn???t feel full as quick as others and I got fatter because of it. I know, I know, pretty dumb, huh?

I???ve been eating Paleo/Primal for about two months and staying VLC all the while. Admittedly, I have bounced back and forth tweaking my diet in a frantic attempt to find that magic combination that would shed fat quickly and ended up gaining about 12 lbs in the process. My final tweak came by way of a three days Atkins ???fat fast??? that ended Tuesday evening. I found the process uneventful and completely do-able, although had I been transitioning directly from a SAD diet I may have felt differently. Anyway things have changed. Could it be that I???ve reset my Leptin sensitivity? I???m hoping it???s not just wishful thinking, but I do feel different. Wednesday I had to push my lunch away after eating about 5 ounces of chicken breast and some asparagus. Thursday four eggs for breakfast held me until dinner without another thought for food. This morning I gave no thought to food until 11am and I never skip breakfast. Is it possible I???ve fixed a life of food abuse?

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 28, 2012
at 07:47 PM

Drop or go up? This is confusing.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 28, 2012
at 07:30 AM

Drop? NO.. go up.

De9cfdb47ff142453b62bc145e44f9c4

on May 27, 2012
at 11:33 PM

Thanks Daphne. I've done A 24 hour IF a few times during the past 60 days and was able to do so without any trouble. I might throw a little IF back into the mix but I'm wary of tweaking too much. I want to stick with what's working until it doesn't work.

De9cfdb47ff142453b62bc145e44f9c4

on May 27, 2012
at 11:25 PM

Thanks Scott. I am confident the changes I'm feel are not just in my head and are here to stay (so long as I stay the course). It's the first time in a long time that I've gone more than a few hours without thinking of food.

De9cfdb47ff142453b62bc145e44f9c4

on May 26, 2012
at 10:23 PM

Thanks for the article Matthew. So, it's a bit of a slippery slope - eat to few calories and the leptin levels will drop and I'll be right were I started?

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4 Answers

1
5447e1f37d3ffa1525dac55be36ee454

on May 26, 2012
at 05:41 PM

It is very possible that you have regained leptin sensitivity. In your first paragraph you described a scenario that is not far off from the truth. Peptide YY is a gut hormone that is released in response to mainly protein, and to a lesser extent fat. Peptide YY has an anoretic effect on people, and though you can feel your stomach about to explode, peptide YY is very low in obese people, so that is why you still have an appetite. Generally the bigger you are the less serum peptide YY you will have. I find that this hormone is far more important in curbing food intake and reducing apptite than leptin, as an increase in serum leptin after a meal occurs several hours after the meal.

In an article I wrote on leptin, I make the case the Peptide YY helps the obese regain CNS sensitivty to leptin, while fructose, aka HFCS or sucrose, destroys leptin sensitivity. So, if you have ditched the sugar, ramped up the protein intake, and if you are losing weight easily, you generally feel good, and you are not overly hungry, then you can say you have probably regained leptin sensitivity. Keep it up!

De9cfdb47ff142453b62bc145e44f9c4

on May 26, 2012
at 10:23 PM

Thanks for the article Matthew. So, it's a bit of a slippery slope - eat to few calories and the leptin levels will drop and I'll be right were I started?

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 28, 2012
at 07:30 AM

Drop? NO.. go up.

4ef079c57d2140bba4dbf4e30240a645

(4413)

on June 28, 2012
at 07:47 PM

Drop or go up? This is confusing.

0
39ff4e45a11194dc5ecad0468a0c1b9a

on May 26, 2012
at 06:01 PM

What you've done is a good standard protocol for correcting any metabolic syndrome issues. I think you're right on with the return of leptin sensitivity and the introduction of ketosis probably was the kick in the pants needed to cause a reset of several involved dependent systems. Congrats!

De9cfdb47ff142453b62bc145e44f9c4

on May 27, 2012
at 11:25 PM

Thanks Scott. I am confident the changes I'm feel are not just in my head and are here to stay (so long as I stay the course). It's the first time in a long time that I've gone more than a few hours without thinking of food.

0
E4f858a9178422502c42b9719690e52c

(603)

on May 26, 2012
at 05:59 PM

Another aspect would be the anorectic effect of ketosis now you've ketoadapted. The flipside is not eating enough and getting faint and weak, or losing lean mass. Don't abuse your new powers :)

0
88cee497750e98a318ebc402ef2c83b0

on May 26, 2012
at 05:33 PM

It's too early to say but it sounds like you are coming on to something. I have just started researching intermittent fasting and how it relates to leptin. You should google it if you havent already. It is fascinating stuff.

De9cfdb47ff142453b62bc145e44f9c4

on May 27, 2012
at 11:33 PM

Thanks Daphne. I've done A 24 hour IF a few times during the past 60 days and was able to do so without any trouble. I might throw a little IF back into the mix but I'm wary of tweaking too much. I want to stick with what's working until it doesn't work.

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