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Is there anything I can do about elevated DHEA-S (plus bonus "borderline" TSH question)?

Answered on June 01, 2015
Created August 21, 2012 at 8:44 PM

I read a lot on this board about low DHEA-S, but not so much about elevated levels in females. I just got back a hormone panel and the only thing that jumps out is:

DHEA-S at 402.1 (NR 98.8 - 340.0)

My TSH is right on the edge of being elevated at 3.01, if you go by the revised guidelines of 0.3 - 3.0 as opposed to the lab ranges.

The DHEA-S has been an ongoing problem for at least five years (when I first had a doc run a panel), and I had birth control pills shoved in my face and my dermatologist tell me I was normal (my levels had snuck down to the high edge of normal).

I am really confused/irritated/blah and am scheduling yet another appointment with yet another doc (the internetz promises she will listen to my problems and run thorough labs), but I wanted to ask the PH community to see if anyone has ever dealt with this problem successfully.

Additionally, aside from that main question, if anyone has any thoughts on high DHEA-S plus borderline TSH...sharing would be appreciated (I was thinking maybe a cortisol issues is in play, but my physiology knowledge is not good enough to make a connection)!

1296f5fecd084f101d7c5fbe013f07eb

(1213)

on August 22, 2012
at 04:03 AM

Sunshine - I did get a full panel run - none of the other results were significant even by liberal standards. (But as soon as I get back to my comp I'll post them - I'm sure I might have missed something!) I'm thinking of booking an appointment with a new doc. The previous couple have been pretty lame (BCP and acne meds with a pat on the head). My husband is a 4th year med student and says this has been a real eye-opener - such an idealist!

6b365c14c646462210f3ef6b6fecace1

(1784)

on August 22, 2012
at 03:21 AM

@blossom, TSH levels aren't really significant without other numbers from a full thyroid panel analysis - Do you have plans of going back to the doc anytime soon?

6b365c14c646462210f3ef6b6fecace1

(1784)

on August 22, 2012
at 03:19 AM

^i agree - plus, cryptic answers are so outdated.

863fbe3ea7cacba9a77b19a09bf445cf

on August 22, 2012
at 02:49 AM

Quilt, unless you're going to be more specific in your comments/answers, please refrain from writing them.

Ed71ab1c75c6a9bd217a599db0a3e117

(25472)

on August 22, 2012
at 01:43 AM

there is a lot you can do.

1296f5fecd084f101d7c5fbe013f07eb

(1213)

on August 21, 2012
at 10:11 PM

Please do! I will try to do the same. The doc who threw BCP at me tested for the late-onset CAH, too, but it came back normal. He said I am "a little PCOS-y." I am not overweight at all, not IR (though I am prone to raging hypoglycemia), I've got mild acne that even Accutane couldn't wipe out permanently..and yeah, I'm a little bit hairier than I'd like. My cycle has been pretty normal with maybe a few long cycles when I've been stressed. It's become more consistent (all 29 days long, lighter, less cramps) since going paleo, though.

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2 Answers

1
2cdd49e87ef8ecffad56a5f6b16f4fee

(30)

on August 21, 2012
at 09:24 PM

I too have high DHEA-S. My TSH wasn't as high though. At first, my ob-gyn diagnosed me with PCOS (she also did a sonogram revealing ovarian cysts) and put me on BC pills. (I exhibit some PCOS symptoms - irregular menses, acne, hirsutism - but I'm not insulin resistant nor overweight, nor do I have thyroid issues. Paleo diet didn't alleviate my symptoms) The pills haven't helped much, so I visited an endocrinologist two weeks ago and she is running more tests - to see about Cushings and late-onset adrenal hyperplasia. My testosterone is low-normal so I'm not a "normal" PCOS case, so she's not sure whether to call it that or not. We shall see. So maybe there is a cortisol issue? I'll try to remember to give an update!

1296f5fecd084f101d7c5fbe013f07eb

(1213)

on August 21, 2012
at 10:11 PM

Please do! I will try to do the same. The doc who threw BCP at me tested for the late-onset CAH, too, but it came back normal. He said I am "a little PCOS-y." I am not overweight at all, not IR (though I am prone to raging hypoglycemia), I've got mild acne that even Accutane couldn't wipe out permanently..and yeah, I'm a little bit hairier than I'd like. My cycle has been pretty normal with maybe a few long cycles when I've been stressed. It's become more consistent (all 29 days long, lighter, less cramps) since going paleo, though.

0
D410ac4e67476f9b365b4812f092a311

on June 01, 2015
at 04:26 PM

alta - what was your result - i'm having the same problem...high dhea-s levels normal everything else - no cysts that i know of though i'm sure some imaging is going to come soon....

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