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How to Reduce SHBG

Answered on August 02, 2017
Created October 09, 2013 at 10:05 PM

Got a blood test: sex hormone binding globulin was very high at 187 nmol/L (reference range is 8 - 114 nmol/L).

Progesterone, estrogen, prolactin, thyroid stimulating hormone, and free testosterone were all in the normal ranges.

Other details: I'm a woman suffering from very low (sometimes nonexistent) sex drive and acne/poor complexion. My menstrual cycle is normal and regular.

What should I do about the SHBG?

(I'm trying to find a naturopath to discuss this issue with, but that's proving difficult.)

6d63a1d0908ded6d7de14c344e68b25d

(45)

on October 10, 2013
at 06:10 AM

Testosterone was definitely at the lower end of the normal range. Total testosterone came out at .8 nmol/L (range: .52 - 2.43) and free testosterone at .4 (anything less than 10.4 is normal).

What I understand is that high SBHG is the cause of low testosterone because it binds to it. I've never taken oral contraceptives, been pregant, or had any of those issues listed. Plus for the past two years I've been eating a nutrient dense primal diet full of fat.

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5 Answers

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0
Cabada701104e9c6d09cbe6d482d748f

on August 02, 2017
at 03:30 PM

Hi Hannah!  just came across your post doing some research.  I alos have shbg of 187 and little to no libido along with low testosterone.  I am meeting with an orthonolecular physician in 2 weeks to discuss--but what have you found out since this post? 

I will be happy to share what i find out in 2 weeks.  He is an amazing doctor.

thank you!
Marisa

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Ccc70fda9cb652cf01f6ebb8cf8ff575

on January 29, 2016
at 07:53 PM

Hi Hannah_15,

Are you on any form of synthetic hormone? ie. birth control. They wreak havoc on your system and your hormones.

What was your prgoesterone and estrogen levels from the test? Progesterone should be around 200 times higher than estrogen. If you are on the pill, you most likely have synthetic progestins. These are deadly and also stop your body from making progesterone endogenously. Also, the pill makes SHBG skyrocket and sometimes it never comes down even coming off the pill. This is why it is essential to supplement with extra progesterone. You cannot take too much as opposed to other hormones.

Please check out Wray White's web site: progesteronetherapy.org

I have been using 300mg progesterone for 5 months and have seen great results. I also have a much increased sense of well-being.

Best regards

0
Medium avatar

on October 10, 2013
at 08:30 PM

Normal ranges don't say much, better is to provide actual values with the reference ranges. You can be hypothyroid and suffer from high prolactin even though both values are in the "normal range".

0
6d63a1d0908ded6d7de14c344e68b25d

on October 10, 2013
at 06:13 AM

Wanted to point out that I don't fit any of the common causes for high SBHG, except for insulin resistance. Insulin insensitivity was an issue for many years, except the past year when I've learned to control it with strategic eating and exercise.

0
543a65b3004bf5a51974fbdd60d666bb

(4493)

on October 10, 2013
at 01:29 AM

don't know myself, but here's a cut&paste from wiki that may give you some ideas,

SHBG levels increase with estrogenic states (oral contraceptives), pregnancy, hyperthyroidism, cirrhosis, anorexia nervosa, and certain drugs. Long-term calorie restriction of more than 50 percent increases SHBG, while lowering free and total testosterone and estradiol.

Was your testosterone at the lower end of the normal range? i was reading that high shbg usually goes hand in hand with low testosterone.

6d63a1d0908ded6d7de14c344e68b25d

(45)

on October 10, 2013
at 06:10 AM

Testosterone was definitely at the lower end of the normal range. Total testosterone came out at .8 nmol/L (range: .52 - 2.43) and free testosterone at .4 (anything less than 10.4 is normal).

What I understand is that high SBHG is the cause of low testosterone because it binds to it. I've never taken oral contraceptives, been pregant, or had any of those issues listed. Plus for the past two years I've been eating a nutrient dense primal diet full of fat.

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